Search Results - "Brown, Alexander K"

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    Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module by Arce, Nicholas A., Cao, Wenpeng, Brown, Alexander K., Legan, Emily R., Wilson, Moriah S., Xu, Emma-Ruoqi, Berndt, Michael C., Emsley, Jonas, Zhang, X. Frank, Li, Renhao

    Published in Nature communications (21-04-2021)
    “…Von Willebrand factor (VWF) activates in response to shear flow to initiate hemostasis, while aberrant activation could lead to thrombosis. Above a critical…”
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    Journal Article
  2. 2

    Development of a Nonhuman Primate (Rhesus Macaque) Model of Uncontrolled Traumatic Liver Hemorrhage by Sheppard, Forest R, Macko, Antoni, Fryer, Darren M, Ozuna, Kassandra M, Brown, Alexander K, Crossland, Randy F, Tadaki, Douglas K

    Published in Shock (Augusta, Ga.) (01-08-2015)
    “…ABSTRACTHemorrhage is the leading cause of potentially survivable trauma mortality, necessitating the development of improved therapeutic interventions. The…”
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    Journal Article