Search Results - "Brown, Alexander"

The Stimulus Selectivity and Connectivity of Layer Six Principal Cells Reveals Cortical Microcircuits Underlying Visual Processing by Vélez-Fort, Mateo, Rousseau, Charly V., Niedworok, Christian J., Wickersham, Ian R., Rancz, Ede A., Brown, Alexander P.Y., Strom, Molly, Margrie, Troy W.

“…Sensory computations performed in the neocortex involve layer six (L6) cortico-cortical (CC) and cortico-thalamic (CT) signaling pathways. Developing an…”
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A randomized controlled trial of dapagliflozin on left ventricular hypertrophy in people with type two diabetes: the DAPA-LVH trial by Brown, Alexander J M, Gandy, Stephen, McCrimmon, Rory, Houston, John Graeme, Struthers, Allan D, Lang, Chim C

“…Abstract Aim We tested the hypothesis that dapagliflozin may regress left ventricular hypertrophy (LVH) in people with type 2 diabetes (T2D). Methods and…”
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APOBEC3A is a prominent cytidine deaminase in breast cancer by Cortez, Luis M, Brown, Amber L, Dennis, Madeline A, Collins, Christopher D, Brown, Alexander J, Mitchell, Debra, Mertz, Tony M, Roberts, Steven A

“…APOBEC cytidine deaminases are the second-most prominent source of mutagenesis in sequenced tumors. Previous studies have proposed that APOBEC3B (A3B) is the…”
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Resource re‐allocation capabilities in internal capital markets: The value of overcoming inertia by Lovallo, Dan, Brown, Alexander L., Teece, David J., Bardolet, David

“…Research summary We examine the correlations between financial resource allocation flow between business segments and two measures of overall firm financial…”
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Enantioselective propargylic [1,3]-rearrangements: copper-catalyzed O -to- N migrations toward C-N bond formation by Cheng, Li-Jie, Brown, Alexander P N, Cordier, Christopher J

“…We have identified an enantioselective copper-catalyzed -to- formal [1,3]-rearrangement to form -propargylic-2-pyridones. This enantioconvergent -to-…”
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Why Do People Volunteer? An Experimental Analysis of Preferences for Time Donations by Brown, Alexander L, Meer, Jonathan, Williams, J. Forrest

“…Why do individuals volunteer their time even when recipients receive far less value than the donor’s opportunity cost? Previous models of altruism that focus…”
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Transnational memory and the Fukushima disaster: Memories of Japan in Australian anti-nuclear activism by Brown, Alexander

“…This paper argues for the importance of transnational memories in framing Australian anti-nuclear activism after the Fukushima disaster. Japan looms large in…”
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Characterization of sequence contexts that favor alternative end joining at Cas9-induced double-strand breaks by Hanscom, Terrence, Woodward, Nicholas, Batorsky, Rebecca, Brown, Alexander J, Roberts, Steven A, McVey, Mitch

“…Abstract Alternative end joining (alt-EJ) mechanisms, such as polymerase theta-mediated end joining, are increasingly recognized as important contributors to…”
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Simulating Ar/He Plasma Sprays of Metal Particles by Brown, Alexander L., Vackel, Andrew

“…A Lagrangian/Eulerian simulation technique for an argon/helium plasma spray including 10–100 micron metal particles has been developed and characterized for…”
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Selective Extraction of Thorium from Rare Earth Elements Using Wrinkled Mesoporous Carbon by Wang, Zijie, Brown, Alexander T, Tan, Kui, Chabal, Yves J, Balkus, Kenneth J

“…Liquid fluoride thorium reactors have been considered as replacements for uranium-based nuclear reactors, having many economic and environmental advantages…”
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Breaking-up should not be hard to do! Designing contracts to avoid wars of attrition by Brown, Alexander L., Van Essen, Matt

“…The partnership dissolution literature has almost entirely focused on the properties of exit mechanisms in isolation taking other features of the break-up…”
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aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data by Niedworok, Christian J., Brown, Alexander P. Y., Jorge Cardoso, M., Osten, Pavel, Ourselin, Sebastien, Modat, Marc, Margrie, Troy W.

“…The validation of automated image registration and segmentation is crucial for accurate and reliable mapping of brain connectivity and function in…”
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ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma by Mao, Peng, Brown, Alexander J., Esaki, Shingo, Lockwood, Svetlana, Poon, Gregory M. K., Smerdon, Michael J., Roberts, Steven A., Wyrick, John J.

“…Recurrent mutations are frequently associated with transcription factor (TF) binding sites (TFBS) in melanoma, but the mechanism driving mutagenesis at TFBS is…”
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Does dapagliflozin regress left ventricular hypertrophy in patients with type 2 diabetes? A prospective, double-blind, randomised, placebo-controlled study by Brown, Alexander J M, Lang, Chim, McCrimmon, Rory, Struthers, Allan

“…Patients with diabetes have a two to fourfold increased risk for development of and death from cardiovascular disease [CVD]. The current oral hypoglycaemic…”
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[Review] Japan in Australia: Culture, Context and Connections by Brown, Alexander

“…This essay is a review of the book 'Japan in Australia: Culture, Context and Connections', edited by David Chapman and Carol Hayes (Routledge, 2020)…”
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The “Who?” Question in the Hate Speech Debate: Part 1: Consistency, Practical, and Formal Approaches by Brown, Alexander

“…This two-part article addresses the “Who?” question in the hate speech debate: namely, which characteristics, social identities or statuses should or should…”
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Associations between right inferior frontal gyrus morphometry and inhibitory control in individuals with nicotine dependence by Brown, Alexander A., Upton, Spencer, Craig, Stephen, Froeliger, Brett

“…The hyperdirect pathway - a circuit involved in executing inhibitory control (IC) - is dysregulated among individuals with nicotine dependence. The right…”
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Role of primary somatosensory cortex in the coding of pain by Vierck, Charles J., Whitsel, Barry L., Favorov, Oleg V., Brown, Alexander W., Tommerdahl, Mark

“…Interactions between subregions of somatosensory cortex during nociceptive stimulation are accompanied by clinically relevant alterations of cortical responses…”
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Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids by Hernandez-Gordillo, Victor, Kassis, Timothy, Lampejo, Arinola, Choi, GiHun, Gamboa, Mario E., Gnecco, Juan S., Brown, Alexander, Breault, David T., Carrier, Rebecca, Griffith, Linda G.

“…Epithelial organoids derived from human donor tissues are important tools in fields ranging from regenerative medicine to drug discovery. Organoid culture…”
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Nucleosome positions establish an extended mutation signature in melanoma by Brown, Alexander J, Mao, Peng, Smerdon, Michael J, Wyrick, John J, Roberts, Steven A

“…Ultraviolet (UV) light-induced mutations are unevenly distributed across skin cancer genomes, but the molecular mechanisms responsible for this heterogeneity…”
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