Search Results - "Brown, Adam S"

Validation of Time in Range as an Outcome Measure for Diabetes Clinical Trials by Beck, Roy W, Bergenstal, Richard M, Riddlesworth, Tonya D, Kollman, Craig, Li, Zhaomian, Brown, Adam S, Close, Kelly L

“…This study evaluated the association of time in range (TIR) of 70-180 mg/dL (3.9-10 mmol/L) with the development or progression of retinopathy and development…”
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A standard database for drug repositioning by Brown, Adam S., Patel, Chirag J.

“…Drug repositioning, the process of discovering, validating, and marketing previously approved drugs for new indications, is of growing interest to academia and…”
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Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring by Bergenstal, Richard M, Beck, Roy W, Close, Kelly L, Grunberger, George, Sacks, David B, Kowalski, Aaron, Brown, Adam S, Heinemann, Lutz, Aleppo, Grazia, Ryan, Donna B, Riddlesworth, Tonya D, Cefalu, William T

“…While A1C is well established as an important risk marker for diabetes complications, with the increasing use of continuous glucose monitoring (CGM) to help…”
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A review of validation strategies for computational drug repositioning by Brown, Adam S, Patel, Chirag J

“…Abstract Repositioning of previously approved drugs is a promising methodology because it reduces the cost and duration of the drug development pipeline and…”
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Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma by Sagers, Jessica E., Brown, Adam S., Vasilijic, Sasa, Lewis, Rebecca M., Sahin, Mehmet I., Landegger, Lukas D., Perlis, Roy H., Kohane, Isaac S., Welling, D. Bradley, Patel, Chirag J., Stankovic, Konstantina M.

“…The computational repositioning of existing drugs represents an appealing avenue for identifying effective compounds to treat diseases with no FDA-approved…”
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A molecular analysis of sand fly blood meals in a visceral leishmaniasis endemic region of northwestern Ethiopia reveals a complex host-vector system by Yared, Solomon, Gebresilassie, Araya, Abbasi, Ibrahim, Aklilu, Essayas, Kirstein, Oscar D., Balkew, Meshesha, Brown, Adam S., Clouse, Ronald M., Warburg, Alon, Hailu, Asrat, Gebre-Michael, Teshome

“…Visceral leishmaniasis (VL, or “kala-azar”) is a major cause of disability and death, especially in East Africa. Its vectors, sand flies (Diptera: Psychodidae:…”
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MeSHDD: Literature-based drug-drug similarity for drug repositioning by Brown, Adam S, Patel, Chirag J

“…Objective: Drug repositioning is a promising methodology for reducing the cost and duration of the drug discovery pipeline. We sought to develop a…”
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A Real-World Prospective Study of the Safety and Effectiveness of the Loop Open Source Automated Insulin Delivery System by Lum, John W, Bailey, Ryan J, Barnes-Lomen, Victoria, Naranjo, Diana, Hood, Korey K, Lal, Rayhan A, Arbiter, Brandon, Brown, Adam S, DeSalvo, Daniel J, Pettus, Jeremy, Calhoun, Peter, Beck, Roy W

“…To evaluate the safety and effectiveness of the Loop Do-It-Yourself automated insulin delivery system. A prospective real-world observational study was…”
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Increasing student engagement with course content in graduate public health education: A pilot randomized trial of behavioral nudges by Garbers, Samantha, Crinklaw, Allyson D., Brown, Adam S., Russell, Roxanne

“…Digital advances in the learning space have changed the contours of student engagement as well as how it is measured. Learning management systems and other…”
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Stigma in People With Type 1 or Type 2 Diabetes by Liu, Nancy F, Brown, Adam S, Folias, Alexandra E, Younge, Michael F, Guzman, Susan J, Close, Kelly L, Wood, Richard

“…This study quantitatively measures diabetes stigma and its associated psychosocial impact in a large population of U.S. patients with type 1 or type 2 diabetes…”
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ksRepo: a generalized platform for computational drug repositioning by Brown, Adam S, Kong, Sek Won, Kohane, Isaac S, Patel, Chirag J

“…Repositioning approved drug and small molecules in novel therapeutic areas is of key interest to the pharmaceutical industry. A number of promising…”
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Fried Chicken, an Airport Ride, and Why Diabetes Is So Hard by Brown, Adam S

“…Brown shares the story of Sam, who was diagnosed with diabetes 16 years ago. Sam has a hard time managing his diabetes because he drinks soda and eat fried…”
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Serotonin promotes exploitation in complex environments by accelerating decision-making by Iwanir, Shachar, Brown, Adam S, Nagy, Stanislav, Najjar, Dana, Kazakov, Alexander, Lee, Kyung Suk, Zaslaver, Alon, Levine, Erel, Biron, David

“…Fast responses can provide a competitive advantage when resources are inhomogeneously distributed. The nematode Caenorhabditis elegans was shown to modulate…”
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Does Time-in-Range Matter? Perspectives From People With Diabetes on the Success of Current Therapies and the Drivers of Improved Outcomes by Runge, Ava S, Kennedy, Lynn, Brown, Adam S, Dove, Abigail E, Levine, Brian J, Koontz, Sophie P, Iyengar, Varun S, Odeh, Sarah A, Close, Kelly L, Hirsch, Irl B, Wood, Richard

“…After assessing patient perspectives on the success of current diabetes therapies and the factors that have the greatest impact on daily life, we show that…”
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aRrayLasso: a network-based approach to microarray interconversion by Brown, Adam S, Patel, Chirag J

“…Robust conversion between microarray platforms is needed to leverage the wide variety of microarray expression studies that have been conducted to date…”
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Polyorchidism with intermittent testicular torsion by Sylvestre, Dana, Brown, Adam S, Conway, Deborah

“…Polyorchidism is rare, with approximately 140 histologically confirmed cases in the literature.1 The most common presentation is triorchidism with intrascrotal…”
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Response to Comment on Bergenstal et al. Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring. Diabetes Care 2018;41:2275-2280 by Bergenstal, Richard M, Beck, Roy W, Close, Kelly L, Grunberger, George, Sacks, David B, Kowalski, Aaron, Brown, Adam S, Heinemann, Lutz, Aleppo, Grazia, Ryan, Donna B, Riddlesworth, Tonya D, Cefalu, William T

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Ureterosciatic hernia by Sylvestr, Dana, Cail, Kenny, Brown, Adam S, Greene, William, Allen, Richard

“…CASE SUMMARY A 71-year-old woman with a history of hypertension, hyperlipidemia, and atrial fibrillation presented to the emergency department with acute,…”
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Leveraging Population‐Based Clinical Quantitative Phenotyping for Drug Repositioning by Brown, Adam S., Rasooly, Danielle, Patel, Chirag J.

“…Computational drug repositioning methods can scalably nominate approved drugs for new diseases, with reduced risk of unforeseen side effects. The majority of…”
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Publisher Correction: Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma by Sagers, Jessica E., Brown, Adam S., Vasilijic, Sasa, Lewis, Rebecca M., Sahin, Mehmet I., Landegger, Lukas D., Perlis, Roy H., Kohane, Isaac S., Welling, D. Bradley, Patel, Chirag J., Stankovic, Konstantina M.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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