Search Results - "Brown, Abraham"

The Economic Impact of Smoking and of Reducing Smoking Prevalence: Review of Evidence by Ekpu, Victor U., Brown, Abraham K.

“…Background Tobacco smoking is the cause of many preventable diseases and premature deaths in the UK and around the world. It poses enormous health- and…”
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Tempol, a Superoxide Dismutase Mimetic, Inhibits Wallerian Degeneration Following Spinal Cord Injury by Preventing Glutathione Depletion and Aldose Reductase Activation by Zeman, Richard J, Brown, Abraham M, Wen, Xialing, Ouyang, Nengtai, Etlinger, Joseph D

“…Spinal cord contusion injury results in Wallerian degeneration of spinal cord axonal tracts, which are necessary for locomotor function. Axonal swelling and…”
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A longitudinal study of policy effect (smoke-free legislation) on smoking norms: ITC Scotland/United Kingdom by Brown, Abraham, Moodie, Crawford, Hastings, Gerard

“…Introduction The longitudinal ITC Scotland/U.K. survey was used to investigate adult smokers' support for smoke-free legislation and whether this support was…”
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Zinc Irreversibly Damages Major Enzymes of Energy Production and Antioxidant Defense Prior to Mitochondrial Permeability Transition by Gazaryan, Irina G., Krasinskaya, Inna P., Kristal, Bruce S., Brown, Abraham M.

“…Recent observations point to the role played by Zn2+ as an inducer of neuronal death. Two Zn2+ targets have been identified that result in inhibition of…”
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Probable Mechanisms of Doxorubicin Antitumor Activity Enhancement by Ginsenoside Rh2 by Popov, Alexander, Klimovich, Anna, Styshova, Olga, Tsybulsky, Alexander, Hushpulian, Dmitry, Osipyants, Andrey, Khristichenko, Anna, Kazakov, Sergey, Ahuja, Manuj, Kaidery, Navneet, Thomas, Bobby, Tishkov, Vladimir, Brown, Abraham, Gazaryan, Irina, Poloznikov, Andrey

“…Ginsenoside Rh2 increases the efficacy of doxorubicin (DOX) treatment in murine models of solid and ascites Ehrlich's adenocarcinoma. In a solid tumor model…”
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Role of the Polyol Pathway in Locomotor Recovery and Wallerian Degeneration after Spinal Cord Contusion Injury by Zeman, Richard J., Wen, Xialing, Ouyang, Nengtai, Brown, Abraham M., Etlinger, Joseph D.

“…Spinal cord contusion injury leads to Wallerian degeneration of axonal tracts, resulting in irreversible paralysis. Contusion injury causes perfusion loss by…”
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Trends and socioeconomic differences in roll-your-own tobacco use: findings from the ITC Europe Surveys by Brown, Abraham K, Nagelhout, Gera E, van den Putte, Bas, Willemsen, Marc C, Mons, Ute, Guignard, Romain, Thompson, Mary E

“…ObjectivesTo examine if exclusive Roll-Your-Own (RYO) tobacco use relative to factory-made (FM) cigarette use has been rising over time, to determine the…”
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Assessment of alcohol problems using AUDIT in a prison setting: more than an 'aye or no' question by MacAskill, Susan, Parkes, Tessa, Brooks, Oona, Graham, Lesley, McAuley, Andrew, Brown, Abraham

“…Alcohol problems are a major UK and international public health issue. The prevalence of alcohol problems is markedly higher among prisoners than the general…”
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The association of normative perceptions with adolescent smoking intentions by Brown, Abraham Kojo, Moodie, Crawford, Hastings, Gerard, Mackintosh, Anne-Marie, Hassan, Louise, Thrasher, James

“…Abstract The social norms approach suggests that tobacco use among a referent population will reduce provided they are presented with accurate information…”
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Zinc Is a Potent Inhibitor of Thiol Oxidoreductase Activity and Stimulates Reactive Oxygen Species Production by Lipoamide Dehydrogenase by Gazaryan, Irina G., Krasnikov, Boris F., Ashby, Gillian A., Thorneley, Roger N.F., Kristal, Bruce S., Brown, Abraham M.

“…Submicromolar zinc inhibits α-ketoglutarate-dependent mitochondrial respiration. This was attributed to inhibition of the α-ketoglutarate dehydrogenase complex…”
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Genome-wide Association Study of Genetic Loci and Alzheimer Disease by Brown, Abraham M, Finch, Stephen J, Gordon, Derek

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Kinetic Model for Ca2+-induced Permeability Transition in Energized Liver Mitochondria Discriminates between Inhibitor Mechanisms by Baranov, Sergei V., Stavrovskaya, Irina G., Brown, Abraham M., Tyryshkin, Alexei M., Kristal, Bruce S.

“…Cytotoxicity associated with pathophysiological Ca2+ overload (e.g. in stroke) appears mediated by an event termed the mitochondrial permeability transition…”
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Intersection between mitochondrial permeability pores and mitochondrial fusion/fission by Gazaryan, Irina G, Brown, Abraham M

“…The goal of this review is to highlight recent developments in the field of mitochondrial membrane processes, which provide new insights into the relation…”
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Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology by Stavrovskaya, Irina G, Narayanan, Malini V, Zhang, Wenhua, Krasnikov, Boris F, Heemskerk, Jill, Young, S Stanley, Blass, John P, Brown, Abraham M, Beal, M Flint, Friedlander, Robert M, Kristal, Bruce S

“…Substantial evidence indicates that mitochondria are a major checkpoint in several pathways leading to neuronal cell death, but discerning critical propagation…”
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The effectiveness of tobacco marketing regulations on reducing smokers' exposure to advertising and promotion: findings from the International Tobacco Control (ITC) Four Country Survey by Kasza, Karin A, Hyland, Andrew J, Brown, Abraham, Siahpush, Mohammad, Yong, Hua-Hie, McNeill, Ann D, Li, Lin, Cummings, K Michael

“…Exposure to tobacco product marketing promotes the initiation, continuation, and reuptake of cigarette smoking and as a result the World Health Organization…”
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Attitudinal and normative responses to advertising stimuli and vaping intentions by Brown, Abraham, Allison, Seamus

“…Empirical data to show whether exposure to e-cigarette advertising stimuli may influence former- and never-smokers to consider vaping is lacking. We examined…”
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pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification by Klyachko, Natalia L, Shchedrina, Valentina A, Efimov, Alexander V, Kazakov, Sergey V, Gazaryan, Irina G, Kristal, Bruce S, Brown, Abraham M

“…Cycling of intracellular pH has recently been shown to play a critical role in ischemia-reperfusion injury. Ischemia-reperfusion also leads to mitochondrial…”
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Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria by Kristal, Bruce S, Conway, Ann D, Brown, Abraham M, Jain, Jinesh C, Ulluci, Paul A, Li, Shu Wen, Burke, William J

“…Parkinson’s disease (PD) is a major cause of age-related morbidity and mortality, present in nearly 1% of individuals at ages 70–79 and ∼2.5% of individuals at…”
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Decoding travellers' willingness to pay more for green travel products: closing the intention-behaviour gap by Agag, Gomaa, Brown, Abraham, Hassanein, Ahmed, Shaalan, Ahmed

“…In the complex context of green consumption, researchers have examined the impact of many variables on pro-environmental behaviours, but have paid little…”
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The mitochondrial permeability transition as a target for neuroprotection by Kristal, Bruce S, Stavrovskaya, Irina G, Narayanan, Malini V, Krasnikov, Boris F, Brown, Abraham M, Beal, M Flint, Friedlander, Robert M

“…Mitochondria serve as checkpoints and amplifiers on cell death pathways. In the central nervous system, mitochondrial involvement seems essential for normal…”
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