Search Results - "Brown, Aaron L."

Total Synthesis of Ustiloxin D Utilizing an Ammonia–Ugi Reaction by Brown, Aaron L, Churches, Quentin I, Hutton, Craig A

“…Total synthesis of the highly functionalized cyclic peptide natural product, ustiloxin D, has been achieved in a convergent manner. Our strategy incorporates…”
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Selective Deletion of the Mechanistic Target of Rapamycin From the Renal Collecting Duct Principal Cell in Mice Down-Regulates the Epithelial Sodium Channel by Chen, Bruce, Fluitt, Maurice B, Brown, Aaron L, Scott, Samantha, Gadicherla, Anirudh, Ecelbarger, Carolyn M

“…The mechanistic target of rapamycin (mTOR), a serine-threonine-specific kinase, is a cellular energy sensor, integrating growth factor and nutrient signaling…”
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A modular framework for implicit 3D–0D coupling in cardiac mechanics by Brown, Aaron L., Salvador, Matteo, Shi, Lei, Pfaller, Martin R., Hu, Zinan, Harold, Kaitlin E., Hsiai, Tzung, Vedula, Vijay, Marsden, Alison L.

“…In numerical simulations of cardiac mechanics, coupling the heart to a model of the circulatory system is essential for capturing physiological cardiac…”
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Computational approaches for mechanobiology in cardiovascular development and diseases by Brown, Aaron L, Sexton, Zachary A, Hu, Zinan, Yang, Weiguang, Marsden, Alison L

“…The cardiovascular development in vertebrates evolves in response to genetic and mechanical cues. The dynamic interplay among mechanics, cell biology, and…”
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Recent advances in quantifying the mechanobiology of cardiac development via computational modeling by Brown, Aaron L., Gerosa, Fannie M., Wang, Jing, Hsiai, Tzung, Marsden, Alison L.

“…Mechanical forces are essential for coordinating cardiac morphogenesis, but much remains to be discovered about the interactions between mechanical forces and…”
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An unusual case of air rifle pellet migration from the brain to the thoracic spine by Lough, Erik G, Glover, Brent, Brown, Aaron L

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Prevention of bile peritonitis by laparoscopic evacuation and lavage after nonoperative treatment of liver injuries by Franklin, Glen A, Richardson, J David, Brown, Aaron L, Christmas, A Britton, Miller, Frank B, Harbrecht, Brian G, Carrillo, Eddy H

“…One of the major lessons learned in the World War II experience with liver injuries was that bile peritonitis was a major factor in morbidity and mortality;…”
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Collecting‐duct‐principal‐cell‐select knockout (KO) of the mechanistic‐target‐of‐rapamycin (mTOR) alters sodium and acid/base homeostasis by Fluitt, Maurice B., Brown, Aaron L., Tiwari, Swasti, Li, Lijun, Ecelbarger, Carolyn M.

“…The mechanistic target of rapamycin (mTOR), a serine‐threonine kinase downstream of insulin receptor signaling and existing in a complex (mTORC2) with…”
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Important role for the mammalian‐target‐of‐rapamycin (mTOR) in the collecting duct as a determinant of transporter/channel profile and function by Brown, Aaron L, Lee, Hwal, Tiwari, Swasti, Li, Lijun, Ecelbarger, Carolyn M.

“…Abstract only mTOR, a serine‐threonine‐specific kinase, is known as a central energy integrator of a number of signaling pathways and may have a role in renal…”
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A Data-Driven, Non-Linear, Parameterized Reduced Order Model of Metal 3D Printing by Brown, Aaron L, Chin, Eric B, Choi, Youngsoo, Khairallah, Saad A, McKeown, Joseph T

“…Directed energy deposition (DED) is a promising metal additive manufacturing technology capable of 3D printing metal parts with complex geometries at lower…”
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A Modular Framework for Implicit 3D-0D Coupling in Cardiac Mechanics by Brown, Aaron L, Salvador, Matteo, Shi, Lei, Pfaller, Martin R, Hu, Zinan, Harold, Kaitlin E, Hsiai, Tzung, Vedula, Vijay, Marsden, Alison L

“…In numerical simulations of cardiac mechanics, coupling the heart to a model of the circulatory system is essential for capturing physiological cardiac…”
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