Search Results - "Brouwer, Thomas B"

Mechanical and structural properties of archaeal hypernucleosomes by Henneman, Bram, Brouwer, Thomas B, Erkelens, Amanda M, Kuijntjes, Gert-Jan, van Emmerik, Clara, van der Valk, Ramon A, Timmer, Monika, Kirolos, Nancy C S, van Ingen, Hugo, van Noort, John, Dame, Remus T

“…Abstract Many archaea express histones, which organize the genome and play a key role in gene regulation. The structure and function of archaeal histone–DNA…”
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Multiplexed Nanometric 3D Tracking of Microbeads Using an FFT-Phasor Algorithm by Brouwer, Thomas B., Hermans, Nicolaas, van Noort, John

“…Many single-molecule biophysical techniques rely on nanometric tracking of microbeads to obtain quantitative information about the mechanical properties of…”
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Single-molecule force spectroscopy on histone H4 tail-cross-linked chromatin reveals fiber folding by Kaczmarczyk, Artur, Allahverdi, Abdollah, Brouwer, Thomas B., Nordenskiöld, Lars, Dekker, Nynke H., van Noort, John

“…The eukaryotic genome is highly compacted into a protein-DNA complex called chromatin. The cell controls access of transcriptional regulators to chromosomal…”
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Rigid Basepair Monte Carlo Simulations of One-Start and Two-Start Chromatin Fiber Unfolding by Force by de Jong, Babette E., Brouwer, Thomas B., Kaczmarczyk, Artur, Visscher, Bert, van Noort, John

“…The organization of chromatin in 30 nm fibers remains a topic of debate. Here, we quantify the mechanical properties of the linker DNA and evaluate the impact…”
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Unraveling DNA Organization with Single-Molecule Force Spectroscopy Using Magnetic Tweezers by Brouwer, Thomas B, Kaczmarczyk, Artur, Pham, Chi, van Noort, John

“…Genomes carry the genetic blueprint of all living organisms. Their organization requires strong condensation as well as carefully regulated accessibility to…”
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Unravelling DNA Organization with Single-Molecule Force Spectroscopy Using Magnetic Tweezers by Brouwer, Thomas B, Kaczmarczyk, Artur, Zarguit, Ilias, Pham, Chi, Dame, Remus T, van Noort, John

“…Genomes carry the genetic blueprint of all living organisms. Their organization requires strong condensation as well as carefully regulated accessibility to…”
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Linker DNA Length Defines the Structure of Chromatin Fibers by Brouwer, Thomas B., Kaczmarczyk, Artur, Hermans, Nicolaas, Botto, Margherita, van Noort, John

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(A)Specific DNA Binding of Archaeal Histones, the Formation and Positioning of Hypernucleosomes by Erkelens, Mandy, Henneman, Bram, Brouwer, Thomas B., Kuijntjes, Gert-Jan A.J.T., van Emmerik, Clara, der Valk, Ramon A. van, Timmer, Monika, Kirolos, Nancy C.S., van Ingen, Hugo, Van Noort, John, Dame, Remus T.

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