Search Results - "Brouwer, Katrien M."

Differential effects of Losartan and Atorvastatin in partial and full thickness burn wounds by Akershoek, Johanneke J, Brouwer, Katrien M, Vlig, Marcel, Boekema, Bouke K H L, Beelen, Rob H J, Middelkoop, Esther, Ulrich, Magda M W

“…Healing of burn wounds is often associated with scar formation due to excessive inflammation and delayed wound closure. To date, no effective treatment is…”
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Effectiveness of Autologous Fat Grafting in Adherent Scars: Results Obtained by a Comprehensive Scar Evaluation Protocol by Jaspers, Mariëlle E. H., Brouwer, Katrien M., van Trier, Antoine J. M., Groot, Marloes L., Middelkoop, Esther, van Zuijlen, Paul P. M.

“…Nowadays, patients normally survive severe traumas such as burn injuries and necrotizing fasciitis. Large skin defects can be closed but the scars remain…”
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Short- and Long-term Outcomes of an Acellular Dermal Substitute versus Standard of Care in Burns and Reconstructions: A Phase I/II Intrapatient Randomized Controlled Trial by Gardien, Kim L. M., Pijpe, Anouk, Brouwer, Katrien M., Stoop, Matthea, Singh, Simarjeet K., Timmermans, Floyd W., Vlig, Marcel, van Zuijlen, Paul P. M., Middelkoop, Esther

“…ABSTRACT OBJECTIVE Dermal substitutes promote dermal regeneration and improve scar quality, but knowledge gaps remain regarding their efficacy and indications…”
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Sustained Postnatal Skin Regeneration Upon Prenatal Application of Functionalized Collagen Scaffolds by Oostendorp, Corien, Geutjes, Paul J, Smit, Frank, Tiemessen, Dorien M, Polman, Sjoerd, Abbawi, Aya, Brouwer, Katrien M, Eggink, Alex J, Feitz, Wout F J, Daamen, Willeke F, van Kuppevelt, Toin H

“…Primary closure of fetal skin in spina bifida protects the spinal cord and improves clinical outcome, but is also associated with postnatal growth…”
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Construction and in vivo evaluation of a dual layered collagenous scaffold with a radial pore structure for repair of the diaphragm by Brouwer, Katrien M., Daamen, Willeke F., van Lochem, Nicole, Reijnen, Daphne, Wijnen, René M.H., van Kuppevelt, Toin H.

“…In each organ the extracellular matrix has a specific architecture and composition, adapted to the functional needs of that organ. As cells are known to…”
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Early intervention by Captopril does not improve wound healing of partial thickness burn wounds in a rat model by Akershoek, Johanneke J.J., Brouwer, Katrien M., Vlig, Marcel, Boekema, Bouke K.H.L, Beelen, Rob H.J., Middelkoop, Esther, Ulrich, Magda M.W.

“…•Inhibition of the Renin Angiotensin System does not influence the inflammatory reaction in the burn wounds.•Inhibition of the Renin Angiotensin System early…”
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Curcumin induces differential expression of cytoprotective enzymes but similar apoptotic responses in fibroblasts and myofibroblasts by Lundvig, Ditte M.S., Pennings, Sebastiaan W.C., Brouwer, Katrien M., Mtaya-Mlangwa, Matilda, Mugonzibwa, Emeria A., Kuijpers-Jagtman, Anne Marie, Von den Hoff, Johannes W., Wagener, Frank A.D.T.G.

“…Excessive extracellular matrix (ECM) deposition and tissue contraction after injury can lead to esthetic and functional problems. Fibroblasts and…”
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Sustainable effectiveness of single‐treatment autologous fat grafting in adherent scars by Jaspers, Mariëlle E.H., Brouwer, Katrien M., van Trier, Antoine J.M., Middelkoop, Esther, van Zuijlen, Paul P.M.

“…Following severe injury, not just the skin but also the subcutis may be destroyed. Consequently, the developing scar can become adherent to underlying…”
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Mechanical cues in orofacial tissue engineering and regenerative medicine by Brouwer, Katrien M., Lundvig, Ditte M. S., Middelkoop, Esther, Wagener, Frank A. D. T. G., Von den Hoff, Johannes W.

“…ABSTRACT Cleft lip and palate patients suffer from functional, aesthetical, and psychosocial problems due to suboptimal regeneration of skin, mucosa, and…”
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Regenerative Medicine for the Respiratory System: Distant Future or Tomorrow's Treatment? by BROUWER, Katrien M, HOOGENKAMP, Henk R, DAAMEN, Willeke F, KUPPEVELT, Toin H. Van

“…Regenerative medicine (RM) is a new field of biomedical science that focuses on the regeneration of tissues and organs and the restoration of organ function…”
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Cytoprotective responses in HaCaT keratinocytes exposed to high doses of curcumin by Lundvig, Ditte M.S., Pennings, Sebastiaan W.C., Brouwer, Katrien M., Mtaya-Mlangwa, Matilda, Mugonzibwa, Emeria, Kuijpers-Jagtman, Anne Marie, Wagener, Frank A.D.T.G., Von den Hoff, Johannes W.

“…Wound healing is a complex process that involves the well-coordinated interactions of different cell types. Topical application of high doses of curcumin, a…”
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Bladder Regeneration Using a Smart Acellular Collagen Scaffold with Growth Factors VEGF, FGF2 and HB-EGF by Roelofs, Luc A J, Oosterwijk, Egbert, Kortmann, Barbara B M, Daamen, Willeke F, Tiemessen, Dorien M, Brouwer, Katrien M, Eggink, Alex J, Crevels, A Jane, Wijnen, Rene M H, van Kuppevelt, Toin H, Geutjes, Paul J, Feitz, Wout F J

“…Tissue engineering may become an alternative to current bladder augmentation techniques. Large scaffolds are needed for clinically significant augmentation,…”
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Collagen-Vicryl scaffolds for reconstruction of the diaphragm in a large animal model by Brouwer, Katrien M., Daamen, Willeke F., Hoogenkamp, Henk R., Geutjes, Paul J., de Blaauw, Ivo, Janssen-Kessels, Wilma, de Boode, Willem, Versteeg, Elly, Wijnen, René M., Feitz, Wout F., Wijnen, Marc, van Kuppevelt, Toin H.

“…Current methods for closure of congenital diaphragmatic hernia using patches are unsatisfactory, and novel collagen-based scaffolds have been developed, and…”
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Heparinized collagen scaffolds with and without growth factors for the repair of diaphragmatic hernia: Construction and in vivo evaluation by Brouwer, Katrien M, Wijnen, René M, Reijnen, Daphne, Hafmans, Theo G, Daamen, Willeke F, van Kuppevelt, Toin H

“…A regenerative medicine approach to restore the morphology and function of the diaphragm in congenital diaphragmatic hernia is especially challenging because…”
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Repair of surgically created diaphragmatic defect in rat with use of a crosslinked porous collagen scaffold by Brouwer, Katrien M., Daamen, Willeke F., Reijnen, Daphne, Verstegen, Ruud H., Lammers, Gerwen, Hafmans, Theo G., Wismans, Ronnie G., van Kuppevelt, Toin H., Wijnen, René M.

“…Large defects in congenital diaphragmatic hernia are closed by patch repair, which is associated with a high complication risk and reherniation rate. New…”
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Evaluation of methods for the construction of collagenous scaffolds with a radial pore structure for tissue engineering by Brouwer, Katrien M., van Rensch, Paul, Harbers, Veroniek E.M., Geutjes, Paul J., Koens, Martin J.W., Wijnen, René M.H., Daamen, Willeke F., van Kuppevelt, Toin H.

“…Type I collagen is used widely as a biomaterial. The structure of collagenous biomaterials, including pore sizes and general architecture, can be varied by a…”
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Mechanical Stress Changes the Complex Interplay Between HO-1, Inflammation and Fibrosis, During Excisional Wound Repair by Cremers, Niels A J, Suttorp, Maarten, Gerritsen, Marlous M, Wong, Ronald J, van Run-van Breda, Coby, van Dam, Gooitzen M, Brouwer, Katrien M, Kuijpers-Jagtman, Anne Marie, Carels, Carine E L, Lundvig, Ditte M S, Wagener, Frank A D T G

“…Mechanical stress following surgery or injury can promote pathological wound healing and fibrosis, and lead to functional loss and esthetic problems. Splinted…”
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Loss of extracellular E-cadherin in the normal mucosa of duodenum and colon of patients with familial adenomatous polyposis by Berkhout, Marloes, Gosens, Marleen J.E.M., Brouwer, Katrien M., Peters, Wilbert H.M., Nagengast, Fokko M., van Krieken, J. Han J.M., Nagtegaal, Iris D.

“…The duodenum is the main site for (pre-) malignant extracolonic manifestations in patients with familial adenomatous polyposis (FAP). Changes in the…”
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P1-048: DHA-enriched diet and cholesterol containing Typical Western Diet influence Alzheimer-like pathology, cognition and the cerebral vasculature in APPSwe /PS1dE9 mice by Hooijmans, Carlijn R, van der Zee, C.E.E.M, Dederen, Pieter J, Reijmer, Yael D, Brouwer, Katrien M, van Groen, Thomas, Broersen, Laus M, Lütjohann, Dieter, Heerschap, Arend, Kiliaan, Amanda J

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Collagen-Vicryl scaffolds for reconstruction of the diaphragm in a large animal model by Brouwer, Katrien M., Daamen, Willeke F., Hoogenkamp, Henk R., Geutjes, Paul J., de Blaauw, Ivo, Janssen-Kessels, Wilma, de Boode, Willem, Versteeg, Elly, Wijnen, René M., Feitz, Wout F., Wijnen, Marc, van Kuppevelt, Toin H.

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