Search Results - "Brouns, A"

Combining a CD20 chimeric antigen receptor and an inducible caspase 9 suicide switch to improve the efficacy and safety of T cell adoptive immunotherapy for lymphoma by Budde, Lihua E, Berger, Carolina, Lin, Yukang, Wang, Jinjuan, Lin, Xubin, Frayo, Shani E, Brouns, Shaunda A, Spencer, David M, Till, Brian G, Jensen, Michael C, Riddell, Stanley R, Press, Oliver W

“…Modification of T cells with chimeric antigen receptors (CAR) has emerged as a promising treatment modality for human malignancies. Integration of…”
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Elderly emergency patients presenting with non-specific complaints: Characteristics and outcomes by Wachelder, Joyce J H, Stassen, Patricia M, Hubens, Laura P A M, Brouns, Steffie H A, Lambooij, Suze L E, Dieleman, Jeanne P, Haak, Harm R

“…Non-specific complaints (NSC) are common at the emergency department, but only a few studies have shown evidence that these complaints are associated with a…”
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Performance of the Manchester triage system in older emergency department patients: a retrospective cohort study by Brouns, Steffie H A, Mignot-Evers, Lisette, Derkx, Floor, Lambooij, Suze L, Dieleman, Jeanne P, Haak, Harm R

“…Studies on the reliability of the MTS and its predictive power for hospitalisation and mortality in the older population have demonstrated mixed results. The…”
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No age thresholds in the emergency department: A retrospective cohort study on age differences by Fuchs, Caro, Çelik, Bilge, Brouns, Steffie H A, Kaymak, Uzay, Haak, Harm R

“…Emergency care in elderly patients has gained attention by researchers due to high utilization rate and the importance of emergency services in elderly care…”
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Organisational Factors Induce Prolonged Emergency Department Length of Stay in Elderly Patients--A Retrospective Cohort Study by Brouns, Steffie H A, Stassen, Patricia M, Lambooij, Suze L E, Dieleman, Jeanne, Vanderfeesten, Irene T P, Haak, Harm R

“…To assess the association of patient and organisational factors with emergency department length of stay (ED-LOS) in elderly ED patients (226565 years old) and…”
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Applicability of the modified Emergency Department Work Index (mEDWIN) at a Dutch emergency department by Brouns, Steffie H A, van der Schuit, Klara C H, Stassen, Patricia M, Lambooij, Suze L E, Dieleman, Jeanne, Vanderfeesten, Irene T P, Haak, Harm R

“…Emergency department (ED) crowding leads to prolonged emergency department length of stay (ED-LOS) and adverse patient outcomes. No uniform definition of ED…”
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Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery by Mastenbroek, T. G., Karel, M. F. A., Nagy, M., Chayoua, W., Korsten, E. I. J., Coenen, D. M., Debets, J., Konings, J., Brouns, A. E., Leenders, P. J. A., van Essen, H., van Oerle, R., Heitmeier, S., Spronk, H. M., Kuijpers, M. J. E., Cosemans, J. M. E. M.

“…While in recent trials the dual pathway inhibition with aspirin plus rivaroxaban has shown to be efficacious in patients with atherosclerotic cardiovascular…”
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Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling by Daniels, A, van Bilsen, M, Janssen, B.J.A, Brouns, A.E, Cleutjens, J.P.M, Roemen, T.H.M, Schaart, G, van der Velden, J, van der Vusse, G.J, van Nieuwenhoven, F.A

“…To identify the initial alterations in myocardial tissue associated with the early signs of diabetic cardiac haemodynamic dysfunction, we monitored changes in…”
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Outcome of elderly emergency department patients hospitalised on weekends - a retrospective cohort study by Brouns, Steffie H A, Wachelder, Joyce J, Jonkers, Femke S, Lambooij, Suze L, Dieleman, Jeanne P, Haak, Harm R

“…Studies investigating different medical conditions and settings have demonstrated mixed results regarding the weekend effect. However, data on the outcome of…”
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Incidence of abdominal pain due to the anterior cutaneous nerve entrapment syndrome in an emergency department by van Assen, Tijmen, Brouns, Jill A G M, Scheltinga, Marc R, Roumen, Rudi M

“…Patients with chronic abdominal pain occasionally suffer from the anterior cutaneous nerve entrapment syndrome (ACNES). A substantial number of patients report…”
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74P RELATION BETWEEN CYTOCHROME P450 (CYP) POLYMORPHISMS AND BIO-AVAILABILITY AND ADVERSE EVENTS (AE) OF TYROSINE KINASE INHIBITORS (TKIS) by Brouns, A, Soetekouw, P, Van den Borne, B, Wijnen, P, Bekers, O, Lankheet, N, Huitema, A, Houben, R, Aerts, J, Dingemans, A

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Inguinal Hernia: Post OP Chronic Pain by Sevonius, D., Montgomery, A., Smedberg, S., Sandblom, G., Zwaans, W., Perquin, C., Roumen, R., Scheltinga, M., Verhagen, T., Loos, M. J. A., Scheltinga, M. R. M., Roumen, R. M. H., Bökkerink, W., Van Laarhoven, C. J. H. M., Koning, G. G., Yang, Z. F., Shen, W. Z., Lu, C., Zheng, W. H., Xiao, W. F., Li, X. R., Narita, M., Matsusue, R., Hata, H., Yamaguchi, T., Otani, T., Ikai, I., Karampinis, I., Weiss, J., Pilz, L., Post, S., Herrle, F., Murphy, J., Yang, F., Meng, L. Q., Meng, X. Z., Chong, Y. Z., Zhao, H. Y., Liu, J. G., van Assen, T., Brouns, J. A. G. M., Scheltinga, M. R., Roumen, R. M.

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Incorporation of differentiated dysplasia improves prediction of oral leukoplakia at increased risk of malignant progression by Wils, Leon J., Poell, Jos B., Evren, Ilkay, Koopman, Marit S., Brouns, Elisabeth R. E. A., de Visscher, Jan G. A. M., Brakenhoff, Ruud H., Bloemena, Elisabeth

“…Oral leukoplakia is the most common oral potentially malignant disorder with a malignant transformation rate into oral squamous cell carcinoma of 1–3%…”
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48P Efficacy of osimertinib (osi) on (prevention of) bone metastases (mets) and skeletal related events (SREs) in patients (pts) with epidermal growth factor receptor mutated (EGFRm+) non-small cell lung cancer (NSCLC) by Brouns, A., Veelen, A.V., Veerman, M., Steendam, C., Dursun, S., Croes, S., Dingemans, A-M.C., Hendriks, L.

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1130P Real-world data of osimertinib (osi) for the treatment of metastatic epidermal growth factor receptor (EGFR+) non-small cell lung cancer (NSCLC) patients (pts), with a focus on age, body mass index (BMI) and trough levels by Veelen, A.V., Veerman, M.G.D., Verschueren, M., Gulikers, J., Brouns, A., Dursun, S., Mathijssen, R.H., Dingemans, A-M.C., Tjan-Heijnen, V.C.G., Peters, B., Souverein, P., Driessen, A., Hendriks, L., van Geel, R., Croes, S.

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Cardiac hypertrophy is enhanced in PPAR -/- mice in response to chronic pressure overload by Smeets, P. J.H., Teunissen, B. E.J., Willemsen, P. H.M., van Nieuwenhoven, F. A., Brouns, A. E., Janssen, B. J.A., Cleutjens, J. P.M., Staels, B., van der Vusse, G. J., van Bilsen, M.

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The delicate balance between over- and underdiagnosis in older people: a simple inguinal hernia? by Brüggemann, Renée A G, Brouns, Steffie H A, Mommers, Elwin H H, Spaetgens, Bart

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Associations between presence of diabetes, mortality and fracture type in individuals with a hip fracture by Spaetgens, Bart, Brouns, Steffie H.A., Linkens, Aimée E.M.J.H., Poeze, Martijn, ten Broeke, René H.M., Brüggemann, Renée A.G., Sipers, Walther, Henry, Ronald M.A., Hanssen, Nordin M.J.

“…•Patients with diabetes display a greatly increased mortality risk after hip fracture.•This increased mortality is not explained by fracture type or…”
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The prevalence of pulmonary embolism in patients with COVID-19 and respiratory decline: A three-setting comparison by Brüggemann, Renée A.G., Spaetgens, Bart, Gietema, Hester A., Brouns, Steffie H.A., Stassen, Patricia M., Magdelijns, Fabienne J., Rennenberg, Roger J., Henry, Ronald M.A., Mulder, Mark M.G., van Bussel, Bas C.T., Schnabel, Ronny M., van der Horst, Iwan C.C., Wildberger, Joachim E., Stehouwer, Coen D.A., ten Cate, Hugo

“…The risk of pulmonary embolism (PE) in patients with Coronavirus Disease 2019 (COVID-19) is recognized. The prevalence of PE in patients with respiratory…”
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A known unknown? Pharmacological prevention of venous thromboembolism in nursing home residents by Brüggemann, Renée A. G., Alnima, Teba, Brouns, Steffie H. A., Hanssen, Nordin M. J., Schols, Jos M. G. A., Cate, Hugo, Spaetgens, Bart, Cate‐Hoek, Arina J.

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