Search Results - "Brouillette, Rachel B"
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TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus
Published in Journal of virology (15-08-2018)“…Lassa virus (LASV) is an Old World arenavirus responsible for hundreds of thousands of infections in West Africa every year. LASV entry into a variety of cell…”
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TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesis
Published in PLoS neglected tropical diseases (01-06-2019)“…T cell immunoglobulin mucin domain-1 (TIM-1) is a phosphatidylserine (PS) receptor, mediating filovirus entry into cells through interactions with PS on…”
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Production of Filovirus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus for Study of Filovirus Entry Mechanisms
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…Members of the family Filoviridae are filamentous, enveloped, and nonsegmented negative-stranded RNA viruses that can cause severe hemorrhagic disease in…”
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Differences in Glycoprotein Complex Receptor Binding Site Accessibility Prompt Poor Cross-Reactivity of Neutralizing Antibodies between Closely Related Arenaviruses
Published in Journal of virology (01-04-2017)“…The glycoprotein complex (GPC) of arenaviruses, composed of stable signal peptide, GP1, and GP2, is the only antigen correlated with antibody-mediated…”
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Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry
Published in Journal of virology (01-07-2016)“…Phosphatidylserine (PtdSer) receptors that are responsible for the clearance of dying cells have recently been found to mediate enveloped virus entry. Ebola…”
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Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans
Published in Genetics (Austin) (01-01-2018)“…Orofacial clefts are one of the most common birth defects, affecting 1-2 per 1000 births, and have a complex etiology. High-resolution array-based comparative…”
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Copy number variation analysis implicates the cell polarity gene glypican 5 as a human spina bifida candidate gene
Published in Human molecular genetics (15-03-2013)“…Neural tube defects (NTDs) are common birth defects of complex etiology. Family and population-based studies have confirmed a genetic component to NTDs…”
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