Search Results - "Brouillette, J."

Multidecadal climate oscillations during the past millennium driven by volcanic forcing by Mann, Michael E, Steinman, Byron A, Brouillette, Daniel J, Miller, Sonya K

“…Past research argues for an internal multidecadal (40- to 60-year) oscillation distinct from climate noise. Recent studies have claimed that this so-termed…”
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Injurious Loading of Articular Cartilage Compromises Chondrocyte Respiratory Function by Coleman, Mitchell C., Ramakrishnan, Prem S., Brouillette, Marc J., Martin, James A.

“…Objective To determine whether repeatedly overloading healthy cartilage disrupts mitochondrial function in a manner similar to that associated with…”
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Factors partitioning physical frailty in people aging with HIV: A classification and regression tree approach by Inceer, Mehmet, Brouillette, Marie‐J., Fellows, Lesley K., Morais, José A., Harris, Marianne, Smaill, Fiona, Smith, Graham, Thomas, Réjean, Mayo, Nancy E.

“…Objective To estimate the extent to which comorbidity and lifestyle factors were associated with physical frailty in middle‐aged and older Canadians living…”
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Increased projected changes in quasi-resonant amplification and persistent summer weather extremes in the latest multimodel climate projections by Guimarães, Sullyandro O., Mann, Michael E., Rahmstorf, Stefan, Petri, Stefan, Steinman, Byron A., Brouillette, Daniel J., Christiansen, Shannon, Li, Xueke

“…High-amplitude quasi-stationary atmospheric Rossby waves with zonal wave numbers 6–8 associated with the phenomenon of quasi-resonant amplification (QRA) have…”
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Torsade de Pointes: are psychotropic drugs at the heart of the matter? A retrospective case-control study led at the Montreal Heart Institute by Laszlo, E., Cyr, S., Tadros, R., Guertin, M.-C., Fiset, C., Brouillette, J.

“…Introduction Psychotropic drugs are the first-line medications in the treatment of psychosis, bipolar, anxiety and depressive disorders. Some of these…”
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A better screening tool for HIV-associated neurocognitive disorders: is it what clinicians need? by Brouillette, Marie-J, Mayo, Nancy, Fellows, Lesley K, Lebedeva, Elena, Higgins, Johanne, Overton, Edgar T, Ances, Beau M, Koski, Lisa

“…OBJECTIVE:Existing screening tools for HIV-Associated Neurocognitive Disorders (HAND) may lack the accuracy required for clinical use. We hypothesized that the…”
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Influence of a novel bm3 corn silage hybrid with floury kernel genetics on lactational performance and feed efficiency of Holstein cows by Coons, E M, Fredin, S M, Cotanch, K W, Dann, H M, Ballard, C S, Brouillette, J P, Grant, R J

“…Dry matter intake, lactation performance, and chewing behavior of multiparous Holstein cows (n = 15) fed diets containing a novel bm3 corn silage hybrid with…”
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Mechanical stress and ATP synthesis are coupled by mitochondrial oxidants in articular cartilage by Wolff, Katherine J., Ramakrishnan, Prem S., Brouillette, Marc J., Journot, Brice J., Mckinley, Todd O., Buckwalter, Joseph A., Martin, James A.

“…Metabolic adaptation of articular cartilage under joint loading is evident and matrix synthesis seems to be critically tied to ATP. Chondrocytes utilize the…”
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Strain-dependent oxidant release in articular cartilage originates from mitochondria by Brouillette, M. J., Ramakrishnan, P. S., Wagner, V. M., Sauter, E. E., Journot, B. J., McKinley, T. O., Martin, J. A.

“…Mechanical loading is essential for articular cartilage homeostasis and plays a central role in the cartilage pathology, yet the mechanotransduction processes…”
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Effect of a 12-Week Mixed Training on Body Quality in People Living with HIV: Does Age and HIV Duration Matter? by Buckinx, F, Granet, J, Bass, A, Kaur, N, Fellows, L. K, Brouillette, M.-J, Mayo, N, Aubertin-Leheudre, Mylene

“…BackgroundThe impact of HIV duration on exercise adaptations has not yet been studied. Moreover, the age at which subjects living with HIV are the most…”
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Finite Element Model-Computed Mechanical Behavior of Femurs with Metastatic Disease Varies Between Physiologic and Idealized Loading Simulations by Johnson, Joshua E, Brouillette, Marc J, Miller, Benjamin J, Goetz, Jessica E

“…Background and objectives: Femurs affected by metastatic bone disease (MBD) frequently undergo surgery to prevent impending pathologic fractures due to…”
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Computerized testing augments pencil‐and‐paper tasks in measuring HIV‐associated mild cognitive impairment by Koski, L, Brouillette, M‐J, Lalonde, R, Hello, B, Wong, E, Tsuchida, A, Fellows, LK

“…Background Existing tools for rapid cognitive assessment in HIV‐positive individuals with mild cognitive deficits lack sensitivity or do not meet psychometric…”
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Methyl Substitution of a Rexinoid Agonist Improves Potency and Reveals Site of Lipid Toxicity by Atigadda, Venkatram R, Xia, Gang, Desphande, Anil, Boerma, LeeAnn J, Lobo-Ruppert, Susan, Grubbs, Clinton J, Smith, Craig D, Brouillette, Wayne J, Muccio, Donald D

“…(2E,4E,6Z,8E)-8-(3′,4′-Dihydro-1′(2′H)-naphthalen-1′-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid, 9cUAB30, is a selective rexinoid that displays substantial…”
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Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention by Muccio, Donald D, Atigadda, Venkatram R, Brouillette, Wayne J, Bland, Kirby I, Krontiras, Helen, Grubbs, Clinton J

“…This review focuses on our efforts to translate a low-toxicity retinoid X receptor-selective agonist, UAB30, to the clinic for the prevention of breast…”
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The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications by Carty, N C, Xu, J, Kurup, P, Brouillette, J, Goebel-Goody, S M, Austin, D R, Yuan, P, Chen, G, Correa, P R, Haroutunian, V, Pittenger, C, Lombroso, P J

“…Glutamatergic signaling through N -methyl- D -aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in glutamatergic signaling are…”
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Sex and strain differences in adult mouse cardiac repolarization: importance of androgens by BROUILLETTE, Judith, RIVARD, Katy, LIZOTTE, Eric, FISET, Céline

“…Gender differences in mouse cardiac repolarization have been reported to be due to the stimulatory action of androgens on the ultrarapid delayed rectifier K(+)…”
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Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention by Desphande, Anil, Xia, Gang, Boerma, LeeAnn J., Vines, Kimberly K., Atigadda, Venkatram R., Lobo-Ruppert, Susan, Grubbs, Clinton J., Moeinpour, Fariba L., Smith, Craig D., Christov, Konstantin, Brouillette, Wayne J., Muccio, Donald D.

“…(2E,4E,6Z,8Z)-8-(3′,4′-Dihydro-1′(2H)-naphthalen-1′-ylidene)-3,7-dimethyl-2,3,6-octatrienoinic acid, 9cUAB30, is a selective rexinoid for the retinoid X…”
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A prospective evaluation of renal replacement therapy modality eligibility by Mendelssohn, David C., Mujais, Salim K., Soroka, Steven D., Brouillette, John, Takano, Tomoko, Barre, Paul E., Mittal, Bharati V., Singh, Ajay, Firanek, Catherine, Story, Ken, Finkelstein, Fredric O.

“…Background. Patient eligibility for renal replacement therapy (RRT) modalities is frequently debated, but little prospective data are available from large…”
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Differential Effects of Superoxide Dismutase Mimetics after Mechanical Overload of Articular Cartilage by Coleman, Mitchell C, Brouillette, Marc J, Andresen, Nicholas S, Oberley-Deegan, Rebecca E, Martin, James M

“…Post-traumatic osteoarthritis can develop as a result of the initial mechanical impact causing the injury and also as a result of chronic changes in mechanical…”
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Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with tau pathology? by Belarbi, K, Burnouf, S, Fernandez-Gomez, F-J, Desmercières, J, Troquier, L, Brouillette, J, Tsambou, L, Grosjean, M-E, Caillierez, R, Demeyer, D, Hamdane, M, Schindowski, K, Blum, D, Buée, L

“…Alzheimer's disease (AD) is a neurodegenerative disorder histologically defined by the cerebral accumulation of amyloid deposits and neurofibrillary tangles…”
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