Search Results - "Brouet, JC"

High-Dose Therapy and Autologous Blood Stem-Cell Transplantation Compared With Conventional Treatment in Myeloma Patients Aged 55 to 65 Years: Long-Term Results of a Randomized Control Trial From the Group Myelome-Autogreffe by FERMAND, Jean-Paul, KATSAHIAN, Sandrine, BELANGER, Coralie, JANVIER, Maud, CHEVRET, Sylvie, BROUET, Jean Claude, RAVAUD, Philippe, DIVINE, Marine, LEBLOND, Veronique, DREYFUS, Francois, MACRO, Margaret, ARNULF, Bertrand, ROYER, Bruno, MARIETTE, Xavier, PERTUISET, Edouard

“…To study the impact of high-dose therapy (HDT) with autologous stem-cell support in patients with symptomatic multiple myeloma (MM) between the ages of 55 and…”
Get full text

High-Dose Therapy and Autologous Peripheral Blood Stem Cell Transplantation in Multiple Myeloma: Up-front or Rescue Treatment? Results of a Multicenter Sequential Randomized Clinical Trial by Fermand, Jean-Paul, Ravaud, Philippe, Chevret, Sylvie, Divine, Marine, Leblond, Véronique, Belanger, Coralie, Macro, Margaret, Pertuiset, Edouard, Dreyfus, François, Mariette, Xavier, Boccacio, Catherine, Brouet, Jean-Claude

“…Results to date indicate that high-dose therapy (HDT) with autologous stem cell support improves survival of patients with symptomatic multiple myeloma (MM)…”
Get full text

High dose chemotherapy in light chain or light and heavy chain deposition disease by Royer, Bruno, Arnulf, Bertrand, Martinez, Frank, Roy, Lydia, Flageul, Béatrice, Etienne, Isabelle, Ronco, Pierre, Brouet, Jean-Claude, Fermand, Jean-Paul

“…High dose chemotherapy in light chain or light and heavy chain deposition disease. Conventional chemotherapy for myeloma yield unsatisfactory results in light…”
Get full text

High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome by Jaccard, Arnaud, Royer, Bruno, Bordessoule, Dominique, Brouet, Jean-Claude, Fermand, Jean-Paul

“…We treated 5 patients with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and multifocal bone lesions…”
Get full text

Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein by LEVY, Y, BROUET, J.-C

“…In this study, we show that IL-10 enhances in vitro the viability of purified splenic B cells. There was a two- to threefold increase in recovery of viable…”
Get full text

Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients by ROUSSELOT, P, LABAUME, S, MAROLLEAU, J.-P, LARGHERO, J, NOGUERA, M.-H, BROUET, J.-C, FERMAND, J.-P

“…Recent data have renewed the interest for arsenic-containing compounds as anticancer agents. In particular, arsenic trioxide (As2O3) has been demonstrated to…”
Get full text

Lymphomas in patients with Sjögren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses by ROYER, B, CAZALS-HATEM, D, SIBILIA, J, AGBALIKA, F, CAYUELA, J.-M, SOUSSI, T, MALOISEL, F, CLAUVEL, J.-P, BROUET, J.-C, MARIETTE, X

“…The occurrence of non-Hodgkin's lymphoma (NHL) is the most serious complication of Sjogren's syndrome (SS). We performed a study of 16 NHLs occurring in…”
Get full text

A clinical and pharmacological study of arsenic trioxide in advanced multiple myeloma patients by ROUSSELOT, P, LARGHERO, J, DOMBRET, H, BROUET, J. Claude, FERMAND, J. Paul, ARNULF, B, POUPON, J, ROYER, B, TIBI, A, MADELAINE-CHAMBRIN, I, CIMERMAN, P, CHEVRET, S, HERMINE, O

“…We previously showed that arsenic trioxide (ATO) and melarsoprol may inhibit the growth of multiple myeloma (MM) cells in vitro and in vivo. We report here the…”
Get full text

Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus by Llorente, L, Zou, W, Levy, Y, Richaud-Patin, Y, Wijdenes, J, Alcocer-Varela, J, Morel-Fourrier, B, Brouet, J C, Alarcon-Segovia, D, Galanaud, P, Emilie, D

“…Interleukin-10 (IL-10) is produced at a high level by B lymphocytes and monocytes of patients with systemic lupus erythematosus (SLE). In the present work, we…”
Get full text

Rifampicin-induced pure red cell aplasia by Mariette, X, Mitjavila, M T, Moulinie, J P, Bussel, A, Brouet, J C, Vainchenker, W, Fermand, J P

Get more information

Study of the B cell memory compartment in common variable immunodeficiency by Brouet, Jean‐Claude, Chedeville, Annick, Fermand, Jean‐Paul, Royer, Bruno

“…We evaluated the B cell memory pool among blood B cells from 20 patients with common variable immunodeficiency (CVID). CD27+ B cell number was normal or…”
Get full text

Are Complicated Forms of Celiac Disease Cryptic T-Cell Lymphomas? by Carbonnel, Franck, Grollet-Bioul, Laurence, Brouet, Jean Claude, Teilhac, Marie Françoise, Cosnes, Jacques, Angonin, Régis, Deschaseaux, Marie, Châtelet, François-Patrick, Gendre, Jean Pierre, Sigaux, François

“…We assessed the clonality of duodenal mucosal T cells in patients with celiac disease and controls. Fifteen adult patients were studied. Four patients had a…”
Get full text

Prognostic value of vertebral lesions detected by magnetic resonance imaging in patients with stage I multiple myeloma by Mariette, Xavier, Zagdanski, Anne‐Marie, Guermazi, Ali, Bergot, Catherine, Arnould, Anne, Frija, Jacques, Brouet, Jean‐Claude, Fermand, Jean‐Paul

“…We assessed the role of spinal magnetic resonance imaging (MRI) and bone densitometry as prognostic factors in patients with asymptomatic stage I multiple…”
Get full text

Phase II trial of arsenic trioxide and alpha interferon in patients with relapsed/refractory adult T-cell leukemia/lymphoma by Hermine, Olivier, Dombret, Hervé, Poupon, Joel, Arnulf, Bertrand, Lefrère, Francois, Rousselot, Phillippe, Damaj, Gandhi, Delarue, Richard, Fermand, Jean Paul, Brouet, Jean Claude, Degos, Laurent, Varet, Bruno, de Thé, Hugues, Bazarbachi, Ali

“…Human T-cell lymphotropic virus type 1 associated adult T-cell leukemia/lymphoma carries a very poor prognosis due to its intrinsic resistance to chemotherapy…”
Get more information

A randomised clinical trial comparing interferon-α and intravenous immunoglobulin in polyneuropathy associated with monoclonal IgM by Mariette, Xavier, Chastang, Claude, Louboutin, Jean-Pierre, Leger, Jean-Marc, Clavelou, Pierre, Brouet, Jean-Claude

“…OBJECTIVES The polyneuropathy associated with a monoclonal IgM directed to the myelin associated glycoprotein (MAG) is a specific entity with a putative causal…”
Get full text

Arsenic trioxide is effective in the treatment of multiple myeloma in SCID mice by Rousselot, Philippe, Larghero, Jérôme, Labaume, Sylvaine, Poupon, Joël, Chopin, Martine, Dosquet, Christine, Marolleau, Jean-Pierre, Janin, Anne, Brouet, Jean-Claude, Fermand, Jean-Paul

“…: Objectives : Pharmacological concentrations of arsenic trioxide (ATO) and organic arsenic melarsoprol induce apoptosis in malignant plasma cells. In an…”
Get full text

The clinicopathological features of extensive small intestinal CD4 T cell infiltration by Carbonnel, F, d’Almagne, H, Lavergne, A, Matuchansky, C, Brouet, J C, Sigaux, F, Beaugerie, L, Nemeth, J, Coffin, B, Cosnes, J, Gendre, J P, Rambaud, J C

“…METHODS Four patients with clinicopathological features suggesting a new distinct entity defining extensive small intestinal CD4 T cell infiltration were…”
Get full text

Plasma exchange and chlorambucil in polyneuropathy associated with monoclonal IgM gammopathy by OKSENHENDLER, E, CHEVRET, S, LEGER, J.-M, LOUBOUTIN, J.-P, BUSSEL, A, BROUET, J.-C

Get full text

Evidence for naive T-cell repopulation despite thymus irradiation after autologous transplantation in adults with multiple myeloma: role of ex vivo CD34+ selection and age by Malphettes, Marion, Carcelain, Guislaine, Saint-Mezard, Pierre, Leblond, Véronique, Altes, Hester Korthals, Marolleau, Jean-Pierre, Debré, Patrice, Brouet, Jean-Claude, Fermand, Jean-Paul, Autran, Brigitte

“…Immunodeficiency following autologous CD34+-purified peripheral blood stem cell (PBSC) transplantation could be related to T-cell depletion of the graft or…”
Get full text

A randomised double blind trial versus placebo does not confirm the benefit of α-interferon in polyneuropathy associated with monoclonal IgM by MARIETTE, XAVIER, BROUET, JEAN-CLAUDE, CHEVRET, SYLVIE, LEGER, JEAN-MARC, CLAVELOU, PIERRE, POUGET, JEAN, VALLAT, JEAN-MARC, VIAL, CHRISTOPHE

Get full text