Search Results - "Brotto, Leticia S."

Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle by Thornton, Angela M, Zhao, Xiaoli, Weisleder, Noah, Brotto, Leticia S, Bougoin, Sylvain, Nosek, Thomas M, Reid, Michael, Hardin, Brian, Pan, Zui, Ma, Jianjie, Parness, Jerome, Brotto, Marco

“…Muscle atrophy alone is insufficient to explain the significant decline in contractile force of skeletal muscle during normal aging. One contributing factor to…”
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Functional and biochemical modifications in skeletal muscles from malarial mice by Brotto, Marco A. P., Marrelli, Mauro T., Brotto, Leticia S., Jacobs‐Lorena, Marcelo, Nosek, Thomas M.

“…Although it is well established that patients suffering from malaria experience skeletal muscle problems (contracture, aches, fatigue, weakness), detailed…”
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Truncation by Glu180 Nonsense Mutation Results in Complete Loss of Slow Skeletal Muscle Troponin T in a Lethal Nemaline Myopathy by Jin, Jian-Ping, Brotto, Marco A., Hossain, M.Moazzem, Huang, Qi-Quan, Brotto, Leticia S., Nosek, Thomas M., Morton, D.Holmes, Crawford, Thomas O.

“…A lethal form of nemaline myopathy, named “Amish Nemaline Myopathy” (ANM), is linked to a nonsense mutation at codon Glu180 in the slow skeletal muscle…”
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Coupled expression of troponin T and troponin I isoforms in single skeletal muscle fibers correlates with contractility by Brotto, Marco A, Biesiadecki, Brandon J, Brotto, Leticia S, Nosek, Thomas M, Jin, Jian-Ping

“…Striated muscle contraction is powered by actin-activated myosin ATPase. This process is regulated by Ca(2+) via the troponin complex. Slow- and fast-twitch…”
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Hypoxia/fatigue-induced degradation of troponin I and troponin C: new insights into physiologic muscle fatigue by de Paula Brotto, M, van Leyen, S A, Brotto, L S, Jin, J P, Nosek, C M, Nosek, T M

“…Conditions such as respiratory failure and cardiopulmonary arrest can expose the diaphragm to hypoxemia. In skeletal muscles, fatiguing stimulation renders…”
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Hypoxia and fatigue-induced modification of function and proteins in intact and skinned murine diaphragm muscle by Brotto, M A, Andreatta-van Leyen, S, Nosek, C M, Brotto, L S, Nosek, T M

“…Fatigue studies of isolated, intact muscles typically utilize solutions saturated with O2. However, under in vivo fatiguing conditions, less oxygen is…”
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Store-Operated Ca2+ Entry (SOCE) Contributes to Normal Skeletal Muscle Contractility in young but not in aged skeletal muscle by Thornton, Angela M, Zhao, Xiaoli, Weisleder, Noah, Brotto, Leticia S., Bougoin, Sylvain, Nosek, Thomas M., Reid, Michael, Hardin, Brian, Pan, Zui, Ma, Jianjie, Parness, Jerome, Brotto, Marco

“…Muscle atrophy alone is insufficient to explain the significant decline in contractile force of skeletal muscle during normal aging. One contributing factor to…”
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Defective maintenance of intracellular Ca homeostasis is linked to increased muscle fatigability in the MG29 null mice

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Alterations in skeletal muscle contractile force following acute exposure to thromboxane A2 by Touchberry, Chad D., Stone, Jessica K., Brotto, Leticia S., Brotto, Marco P., Wacker, Michael J.

“…Abstract only Thromboxane A2 (TxA2) has traditionally been associated with platelet aggregation and vasoconstriction of the microcirculation. A variety of…”
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Defective maintenance of intracellular Ca2+ homeostasis is linked to increased muscle fatigability in the MG29 null mice by Brotto, Marco A P, Nagaraj, Ramakrishnan Y, Brotto, Leticia S, Takeshima, Hiroshi, Ma, Jian Jie, Nosek, Thomas M

“…Mitsugumin 29 (MG29) is a transmembrane protein that is normally found in the triad junction of skeletal muscle. Our previous studies have shown that targeted…”
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