Search Results - "Brothers, Rowan O."

Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries by Pybus, Alyssa F, Bitarafan, Sara, Brothers, Rowan O, Rohrer, Alivia, Khaitan, Arushi, Moctezuma, Felix Rivera, Udeshi, Kareena, Davies, Brae, Triplett, Sydney, Griffin, Martin N, Dammer, Eric B, Rangaraju, Srikant, Buckley, Erin M, Wood, Levi B

“…Repetitive mild traumatic brain injuries (rmTBI) sustained within a window of vulnerability can result in long term cognitive deficits, depression, and…”
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Quantifying the Cerebral Hemometabolic Response to Blood Transfusion in Pediatric Sickle Cell Disease With Diffuse Optical Spectroscopies by Lee, Seung Yup, Brothers, Rowan O., Turrentine, Katherine B., Quadri, Ayesha, Sathialingam, Eashani, Cowdrick, Kyle R., Gillespie, Scott, Bai, Shasha, Goldman-Yassen, Adam E., Joiner, Clinton H., Brown, R. Clark, Buckley, Erin M.

“…Red blood cell transfusions are common in patients with sickle cell disease who are at increased risk of stroke. Unfortunately, transfusion thresholds needed…”
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Diffuse Optical Spectroscopy Assessment of Resting Oxygen Metabolism in the Leg Musculature by Boebinger, Scott E., Brothers, Rowan O., Bong, Sistania, Sanders, Bharat, McCracken, Courtney, Ting, Lena H., Buckley, Erin M.

“…We lack reliable methods to continuously assess localized, resting-state muscle activity that are comparable across individuals. Near-infrared spectroscopy…”
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The influence of voxelotor on cerebral blood flow and oxygen extraction in pediatric sickle cell disease by Brothers, Rowan O., Turrentine, Katherine B., Akbar, Mariam, Triplett, Sydney, Zhao, Hongting, Urner, Tara M., Goldman-Yassen, Adam, Jones, Richard A., Knight-Scott, Jack, Milla, Sarah S., Bai, Shasha, Tang, Amy, Brown, R. Clark, Buckley, Erin M.

“…•Optical measurements of cerebral blood flow are validated against perfusion MRI in pediatric SCA.•Voxelotor significantly decreases OEF and cerebral blood…”
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Impaired cerebrovascular reactivity in pediatric sickle cell disease using diffuse correlation spectroscopy by Cowdrick, Kyle R, Akbar, Mariam, Boodooram, Tisha, Harris, LaBeausha H, Bai, Shasha, Brothers, Rowan O, Arrington, Michael, Lee, Seung Yup, Khemani, Kirsma, Gee, Beatrice, Buckley, Erin M

“…Cerebrovascular reactivity (CVR), defined as the ability of cerebral vasculature to dilate in response to a vasodilatory stimulus, is an integral mechanism in…”
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Normative cerebral microvascular blood flow waveform morphology assessed with diffuse correlation spectroscopy by Urner, Tara M, Cowdrick, Kyle R, Brothers, Rowan O, Boodooram, Tisha, Zhao, Hongting, Goyal, Vidisha, Sathialingam, Eashani, Quadri, Ayesha, Turrentine, Katherine, Akbar, Mariam M, Triplett, Sydney E, Bai, Shasha, Buckley, Erin M

“…Microvascular cerebral blood flow exhibits pulsatility at the cardiac frequency that carries valuable information about cerebrovascular health. This study used…”
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Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury by Brothers, Rowan O, Bitarafan, Sara, Pybus, Alyssa F, Wood, Levi B, Buckley, Erin M

“…Mild traumatic brain injuries (mTBIs) are a significant public health problem. Repeated exposure to mTBI can lead to cumulative, long-lasting functional…”
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Stand-alone segmentation of blood flow pulsatility measured with diffuse correlation spectroscopy by Bharadwaj, Srinidhi, Urner, Tara M, Cowdrick, Kyle R, Brothers, Rowan O, Boodooram, Tisha, Zhao, Hongting, Goyal, Vidisha, Sathialingam, Eashani, Wu, Yueh-Chi, Quadri, Ayesha, Turrentine, Katherine, Akbar, Mariam M, Triplett, Sydney E, Bai, Shasha, Buckley, Erin M

“…We present a stand-alone blood flow index (BFI) pulse segmentation method for diffuse correlation spectroscopy that uses a wavelet-based representation of the…”
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Cerebrovascular reactivity measured in awake mice using diffuse correlation spectroscopy by Brothers, Rowan O, Atlas, Nir, Cowdrick, Kyle R, Buckley, Erin M

“…Significance: Cerebrovascular reactivity (CVR), defined as the ability of the cerebral vasculature to dilate or constrict in response to a vasoactive stimulus,…”
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Cerebral Metabolic Stress Improves after Voxelotor Treatment in Pediatric Sickle Cell Disease by Brothers, Rowan O., Turrentine, Katherine B., Akbar, Mariam, Triplett, Sydney, Urner, Tara M., Tang, Amy Y., Brown, Clark, Buckley, Erin M.

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Assessment of Cerebral Blood Flow and Oxygen Extraction in Pediatric Sickle Cell Disease with Non-Invasive Diffuse Optical Spectroscopies by Lee, Seung Yup, Sathilingam, Eashani, Cowdrick, Kyle R., Brothers, Rowan O., Lam, Wilbur A., Brown, R. Clark, Joiner, Clinton H., Morris, Claudia R., Buckley, Erin M.

“…Introduction: Cerebral infarcts and associated cognitive impairments are a devastating consequence of sickle cell disease (SCD). While the underlying…”
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