Search Results - "Brosius, Stephanie"

Clinical Reasoning: A 12-Month-Old Male Child With Staring Episodes, Ataxia, and Right-sided Weakness by Brosius, Stephanie N., Otto, William, Waldman, Amy, Russo, Michael, McGuire, Jennifer

“…Baylisascaris procyonis , or raccoon roundworm, is a rare cause of eosinophilic meningoencephalitis with historically poor clinical outcomes. Symptoms of…”
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Neuroimaging and Management of Pediatric Cancer Survivors Treated With Cranial Radiation: Consensus Recommendations When Evidence Is Sparse by Brosius, Stephanie N., Benedetti, Giulia M., Beslow, Lauren A.

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Health‐related quality of life of children born to childhood cancer survivors in Germany by Balcerek, Magdalena, Sommerhäuser, Greta, Schilling, Ralph, Hölling, Heike, Klco‐Brosius, Stephanie, Borgmann‐Staudt, Anja

“…Objective Rising childhood cancer survival rates have increased the importance of health‐related quality of life (HRQL) assessment. While survivors show…”
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Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas by Dougherty, Jacquelyn, Harvey, Kyra, Liou, Angela, Labella, Katherine, Moran, Deborah, Brosius, Stephanie, De Raedt, Thomas

“…Neurofibromatosis Type 1 (NF1) patients develop an array of benign and malignant tumors, of which Malignant Peripheral Nerve Sheath Tumors (MPNST) and High…”
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Characteristics of Moyamoya Syndrome in Pediatric Patients With Neurofibromatosis Type 1 by Brosius, Stephanie N., Vossough, Arastoo, Fisher, Michael J., Lang, Shih-Shan, Beslow, Lauren A., George, Brandon J., Ichord, Rebecca

“…Moyamoya syndrome (MMS) is a progressive cerebral arteriopathy with increased incidence in children with neurofibromatosis type 1 (NF1). Despite the potential…”
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Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line by Longo, Jody Fromm, Brosius, Stephanie N., Znoyko, Iya, Alers, Victoria A., Jenkins, Dorea P., Wilson, Robert C., Carroll, Andrew J., Wolff, Daynna J., Roth, Kevin A., Carroll, Steven L.

“…Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive Schwann cell-derived neoplasms that occur sporadically or in patients with neurofibromatosis…”
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Fertility knowledge and associated empowerment following an educational intervention for adolescent cancer patients by Borgmann‐Staudt, Anja, Kunstreich, Marina, Schilling, Ralph, Balcerek, Magdalena, Dirksen, Uta, Cario, Holger, Kepakova, Katerina, Klco‐Brosius, Stephanie, Korte, Elisabeth, Kruseova, Jarmila, Lackner, Herwig, Langer, Thorsten, Roslan, Katarzyna‐Muszynska, Stefanowicz, Joanna, Strauß, Gabriele, Byrne, Julianne

“…Introduction/Objectives Fertility preservation is a major concern for adolescent cancer patients; yet, educational gaps remain. Our intervention study examined…”
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R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells by Weber, Shannon M, Brossier, Nicole M, Prechtl, Amanda, Barnes, Stephen, Wilson, Landon S, Brosius, Stephanie N, Longo, Jody Fromm, Carroll, Steven L

“…Loss of the Ras GTPase-activating protein neurofibromin promotes nervous system tumor pathogenesis in patients with neurofibromatosis type 1 (NF1)…”
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Reversible improvement in severe freezing of gait from Parkinson's disease with unilateral interleaved subthalamic brain stimulation by Brosius, Stephanie N, Gonzalez, Christopher L, Shuresh, Joshita, Walker, Harrison C

“…Abstract Freezing of gait causes considerable morbidity in patients with Parkinson's disease and is often refractory to conventional treatments. In this…”
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ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms by Longo, Jody Fromm, Brosius, Stephanie N, Black, Laurel, Worley, Stuart H, Wilson, Robert C, Roth, Kevin A, Carroll, Steven L

“…We have found that erbB receptor tyrosine kinases drive Ras hyperactivation and growth in NF1-null malignant peripheral nerve sheath tumors (MPNSTs). However,…”
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Management and Outcome of Ewing Sarcoma of the Head and Neck by Grevener, Knut, Haveman, Lianne M., Ranft, Andreas, van den Berg, Henk, Jung, Susanne, Ladenstein, Ruth, Klco-Brosius, Stephanie, Juergens, Heribert, Merks, J Hans M., Dirksen, Uta

“…Background Ewing sarcoma (EWS) of the head and neck is rare. Multimodal treatment consists of chemotherapy and local treatment; however, local treatment for…”
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Fertility education for adolescent cancer patients: Gaps in current clinical practice in Europe by Korte, Elisabeth, Schilling, Ralph, Balcerek, Magdalena, Campbell, Helen, Dirksen, Uta, Herrmann, Gloria, Kepakova, Katerina, Kepak, Tomas, Klco‐Brosius, Stephanie, Kruseova, Jarmila, Kunstreich, Marina, Lackner, Herwig, Langer, Thorsten, Panasiuk, Anna, Stefanowicz, Joanna, Strauß, Gabriele, Ranft, Andreas, Byrne, Julianne, Goldbeck, Lutz, Borgmann‐Staudt, Anja

“…Objective As adolescent cancer patients may suffer from infertility following treatment, fertility counselling is essential. Our aim was to explore the current…”
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Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I by Li, Kairong, Turner, Ashley N, Chen, Min, Brosius, Stephanie N, Schoeb, Trenton R, Messiaen, Ludwine M, Bedwell, David M, Zinn, Kurt R, Anastasaki, Corina, Gutmann, David H, Korf, Bruce R, Kesterson, Robert A

“…Neurofibromatosis type 1 (NF1) is a common genetic disorder characterized by the occurrence of nerve sheath tumors and considerable clinical heterogeneity…”
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Combinatorial Therapy With Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades by Brosius, Stephanie N, Turk, Amy N, Byer, Stephanie J, Longo, Jody Fromm, Kappes, John C, Roth, Kevin A, Carroll, Steven L

“…ABSTRACTChemotherapeutic agents effective against malignant peripheral nerve sheath tumors (MPNSTs) are urgently needed. We recently found that tamoxifen…”
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The relation of radiological tumor volume response to histological response and outcome in patients with localized Ewing Sarcoma by Haveman, Lianne M., Ranft, Andreas, vd Berg, Henk, Smets, Anne, Kruseova, Jarmila, Ladenstein, Ruth, Brichard, Benedicte, Paulussen, Michael, Kuehne, Thomas, Juergens, Heribert, Klco‐Brosius, Stephanie, Dirksen, Uta, Merks, Johannes H.M.

“…Background Magnetic resonance imaging (MRI) is the modality of choice for local staging and response evaluation of Ewing sarcoma (EwS). Aim of this study was…”
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Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells by Brossier, Nicole M., Prechtl, Amanda M., Longo, Jody Fromm, Barnes, Stephen, Wilson, Landon S., Byer, Stephanie J., Brosius, Stephanie N., Carroll, Steven L.

“…Neurofibromin, the tumor suppressor encoded by the neurofibromatosis type 1 (NF1) gene, potentially suppresses the activation of H-Ras, N-Ras, and K-Ras…”
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A continuing clinical education course to maintain clinical competencies and foster new clinical knowledge during the graduate school years of MD-PhD training by Cochrane, Graham D, Anwar, Shima D, Weaver, Alice N, Brosius, Stephanie N, Poholek, Catherine H, Allen, Heather, Seay, Randy L, Lorenz, Robin G, Payne, Gregory A, Geisler, William M

“…Most students in MD-PhD programs take a leave of absence from medical school to complete PhD training, which promotes a natural loss of clinical skills and…”
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Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis by Brosius, Stephanie N., Turk, Amy N., Byer, Stephanie J., Brossier, Nicole M., Kohli, Latika, Whitmire, Amber, Mikhail, Fady M., Roth, Kevin A., Carroll, Steven L.

“…Malignant peripheral nerve sheath tumors (MPNSTs) are Schwann cell-derived malignancies that arise from plexiform neurofibromas in patients with mutation of…”
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Parenthood for childhood cancer survivors: unfounded fear of cancer development in offspring and related health behaviors by Dalkner, Nina, Fleischmann, Eva, Borgmann-Staudt, Anja, Fürschuß, Christine, Klco-Brosius, Stephanie, Kepakova, Katerina, Kruseova, Jarmila, Lackner, Herwig, Michel, Gisela, Mohapp, Andrea, Nagele, Eva, Panasiuk, Anna, Tamesberger, Melanie, Reininghaus, Eva Z, Wiegele, Karin, Balcerek, Magdalena

“…Current literature reveals no increased risk for adverse non-hereditary health outcomes in the offspring of childhood cancer survivors (CCS), yet survivors…”
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The Use of Assisted Reproductive Technology by European Childhood Cancer Survivors by Borgmann-Staudt, Anja, Michael, Simon, Sommerhaeuser, Greta, Fernández-González, Marta-Julia, Friedrich, Lucía Alacán, Klco-Brosius, Stephanie, Kepak, Tomas, Kruseova, Jarmila, Michel, Gisela, Panasiuk, Anna, Schmidt, Sandrin, Lotz, Laura, Balcerek, Magdalena

“…CCS often wish to have biological children yet harbour concerns about fertility impairment, pregnancy risks and the general health risks of prospective…”
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