Search Results - "Brooks, Monica T."
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The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain
Published in Structure (London) (11-08-2010)“…RIG-I is a cytosolic sensor of viral RNA that plays crucial roles in the induction of type I interferons. The C-terminal domain (CTD) of RIG-I is responsible…”
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The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA
Published in The Journal of biological chemistry (15-05-2009)“…The RIG-I-like receptors (RLRs), RIG-I and MDA5, recognize single-stranded RNA with 5′ triphosphates and double-stranded RNA (dsRNA) to initiate innate…”
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Recognition of Galactose-Deficient O-Glycans in the Hinge Region of IgA1 by N-Acetylgalactosamine-Specific Snail Lectins: A Comparative Binding Study
Published in Biochemistry (Easton) (13-07-2010)“…Aberrancies in IgA1 glycosylation have been linked to the pathogenesis of IgA nephropathy (IgAN), a kidney disease characterized by deposits of IgA1-containing…”
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Convulxin Forms a Dimer in Solution and Can Bind Eight Copies of Glycoprotein VI: Implications for Platelet Activation
Published in Biochemistry (Easton) (07-04-2009)“…Convulxin (CVX) is a C-type lectin-like protein from the venom of the South American rattlesnake that functions as a potent agonist of the platelet collagen…”
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The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNAS
Published in The Journal of biological chemistry (15-05-2009)“…The RIG-I-like receptors (RLRs), RIG-I and MDA5, recognize single-stranded RNA with 5′ triphosphates and double-stranded RNA (dsRNA) to initiate innate…”
Get full text
Journal Article