Search Results - "Brooks, Leonard A"

Derivation of induced pluripotent stem cells from ferret somatic cells by Gao, Jinghui, Petraki, Sophia, Sun, Xingshen, Brooks, Leonard A, Lynch, Thomas J, Hsieh, Chih-Lin, Elteriefi, Reem, Lorenzana, Zareeb, Punj, Vasu, Engelhardt, John F, Parekh, Kalpaj R, Ryan, Amy L

“…Ferrets are an attractive mammalian model for several diseases, especially those affecting the lungs, liver, brain, and kidneys. Many chronic human diseases…”
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Intra-arrest hypothermia: Both cold liquid ventilation with perfluorocarbons and cold intravenous saline rapidly achieve hypothermia, but only cold liquid ventilation improves resumption of spontaneous circulation by Riter, Henry G, Brooks, Leonard A, Pretorius, Andrew M, Ackermann, Laynez W, Kerber, Richard E

“…Abstract Background Rapid intra-arrest induction of hypothermia using total liquid ventilation (TLV) with cold perfluorocarbons improves resuscitation outcome…”
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Perfluorocarbon induced intra-arrest hypothermia does not improve survival in a swine model of asphyxial cardiac arrest by Albaghdadi, Ali S, Brooks, Leonard A, Pretorius, Andrew M, Kerber, Richard E

“…Abstract Background Pulseless electrical activity is an important cause of cardiac arrest. Our purpose was to determine if induction of hypothermia with a cold…”
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Liquid ventilation with perfluorocarbons facilitates resumption of spontaneous circulation in a swine cardiac arrest model by Staffey, Kimberly S, Dendi, Raghuveer, Brooks, Leonard A, Pretorius, Andrew M, Ackermann, Laynez W, Zamba, K.D, Dickson, Eric, Kerber, Richard E

“…Summary Background Induced external hypothermia during ventricular fibrillation (VF) improves resuscitation outcomes. Our objectives were twofold (1) to…”
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Mechanism of coronary microvascular responses to metabolic stimulation by EMBREY, R. P, BROOKS, L. A, DELLSPERGER, K. C

“…Previous studies from our laboratory have shown that coronary microvascular dilation to increased myocardial oxygen consumption (MVO2) is greater in vessels <…”
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Cytochrome P-450 pathway in acetylcholine-induced canine coronary microvascular vasodilation in vivo by Widmann, M D, Weintraub, N L, Fudge, J L, Brooks, L A, Dellsperger, K C

“…In the canine coronary microcirculation, acetylcholine (ACh)-induced vasodilation of large (> or = 100 microns) epicardial arterioles (LgA), but not small (<…”
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Abstract 2009: Matching the Transthoracic Defibrillation Vector to the Fibrillation Vector Improves Shock Success by Brooks, Leonard A, Zhang, Yi, Dendi, Raghuveer, Anderson, Roger H, Kerber, Richard E

“…Abstract only Background: Depolarization of myocytes requires less energy when electrical current flows along the longitudinal axis compared to the transverse…”
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Free radicals mediate endothelial dysfunction of coronary arterioles in diabetes by AMMAR, R. F, GUTTERMAN, D. D, BROOKS, L. A, DELLSPERGER, K. C

“…Previous studies have demonstrated that vascular responses to acetylcholine (ACh) are impaired in diabetes mellitus (DM). Since reactive oxygen species (ROS)…”
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Ischemia-reperfusion impairs endothelium-dependent relaxation of coronary microvessels but does not affect large arteries by QUILLEN, J. E, SELLKE, F. W, BROOKS, L. A, HARRISON, D. G

“…We examined the effects of ischemia with and without reperfusion on endothelium-dependent and -independent vascular relaxation in both conduit and resistance…”
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Endothelial modulation of the coronary vasculature in vessels perfused via mature collaterals by SELLKE, F. W, QUILLEN, J. E, BROOKS, L. A, HARRISON, D. G

“…Previous in vivo studies have shown that vasopressin, which releases the endothelium-derived relaxing factor and constricts coronary smooth muscle, produces…”
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Response of coronary microvascular collaterals to activation of ATP-sensitive K+ channels by Lamping, K G, Nuno, D W, Brooks, L A, Fujii, M

“…Studies have suggested that collateral vessels of the coronary and hind-limb circulations are more sensitive to activation of ATP-sensitive K+ channels than…”
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Thromboxane contributes to submaximal coronary dilation during myocardial ischemia by Eller, B T, Brooks, L A, Dellsperger, K C

“…Thromboxane has been shown to contribute to coronary constriction in conduit coronary arteries during platelet aggregation at the site of a critical stenosis…”
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