Search Results - "Brooks, G J"

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial by Dunning, Jake, Sahr, Foday, Rojek, Amanda, Gannon, Fiona, Carson, Gail, Idriss, Baimba, Massaquoi, Thomas, Gandi, Regina, Joseph, Sebatu, Osman, Hassan K, Brooks, Timothy J G, Simpson, Andrew J H, Goodfellow, Ian, Thorne, Lucy, Arias, Armando, Merson, Laura, Castle, Lyndsey, Howell-Jones, Rebecca, Pardinaz-Solis, Raul, Hope-Gill, Benjamin, Ferri, Mauricio, Grove, Jennifer, Kowalski, Mark, Stepniewska, Kasia, Lang, Trudie, Whitehead, John, Olliaro, Piero, Samai, Mohammed, Horby, Peter W

“…TKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety…”
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Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study by Semper, Amanda E, Broadhurst, M Jana, Richards, Jade, Foster, Geraldine M, Simpson, Andrew J H, Logue, Christopher H, Kelly, J Daniel, Miller, Ann, Brooks, Tim J G, Murray, Megan, Pollock, Nira R

“…Throughout the Ebola virus disease (EVD) epidemic in West Africa, field laboratory testing for EVD has relied on complex, multi-step real-time reverse…”
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Diagnosis of Ebola Virus Disease: Past, Present, and Future by Broadhurst, M Jana, Brooks, Tim J G, Pollock, Nira R

“…Laboratory diagnosis of Ebola virus disease plays a critical role in outbreak response efforts; however, establishing safe and expeditious testing strategies…”
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UK hantavirus, renal failure, and pet rats by Taori, Surabhi K, Dr, Jameson, Lisa J, MSc, Campbell, Andrew, FRCA, Drew, Peter J, MD, McCarthy, Noel D, DPhil, Hart, Judy, FFPH, Osborne, Jane C, PhD, Sudhanva, Malur, FRCPath, Brooks, Timothy JG, FRCpath

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The demographics and geographic distribution of laboratory-confirmed Lyme disease cases in England and Wales (2013–2016): an ecological study by Tulloch, John S P, Semper, Amanda E, Brooks, Tim J G, Russell, Katherine, Halsby, Kate D, Christley, Robert M, Radford, Alan D, Vivancos, Roberto, Warner, Jenny C

“…ObjectiveLyme disease is a tick-borne disease of increasing incidence and public concern across the Northern Hemisphere. However, the socio-demographics and…”
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Impact of prior SARS-CoV-2 infection and COVID-19 vaccination on the subsequent incidence of COVID-19: a multicentre prospective cohort study among UK healthcare workers – the SIREN (Sarscov2 Immunity & REinfection EvaluatioN) study protocol by Wallace, Sarah, Hall, Victoria, Charlett, Andre, Kirwan, Peter D, Cole, Michele, Gillson, Natalie, Atti, Ana, Timeyin, Jean, Foulkes, Sarah, Taylor-Kerr, Andrew, Andrews, Nick, Shrotri, Madhumita, Rokadiya, Sakib, Oguti, Blanche, Vusirikala, Amoolya, Islam, Jasmin, Zambon, Maria, Brooks, Tim J G, Ramsay, Mary, Brown, Colin S, Chand, Meera, Hopkins, Susan

“…IntroductionUnderstanding the effectiveness and durability of protection against SARS-CoV-2 infection conferred by previous infection and COVID-19 is essential…”
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Anthrax infection in drug users by Booth, Malcolm G, Hood, John, Brooks, Timothy JG, Hart, Andrew

“…Since December, 2009, 31 cases of anthrax infection have been confirmed in heroin users in Scotland, with 11 deaths. Findings differ from classic necrotising…”
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Presymptomatic Prediction of Sepsis in Intensive Care Unit Patients by Lukaszewski, R A, Yates, A M, Jackson, M C, Swingler, K, Scherer, J M, Simpson, A J, Sadler, P, McQuillan, P, Titball, R W, Brooks, T J G, Pearce, M J

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Assessing filtering of mountaintop CO2 mole fractions for application to inverse models of biosphere-atmosphere carbon exchange by Brooks, B.-G J, Desai, A R, Stephens, B B, Bowling, D R, Burns, S P, Watt, A S, Heck, S L, Sweeney, C

“…There is a widely recognized need to improve our understanding of biosphere-atmosphere carbon exchanges in areas of complex terrain including the United States…”
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Evaluation of azithromycin, trovafloxacin and grepafloxacin as prophylaxis against experimental murine Brucella melitensis infection by Atkins, Helen S, Spencer, Stephen, Brew, Simon D, Jenner, Dominic C, Sefton, Armine M, MacMillan, Alastair P, Brooks, Timothy J.G, Simpson, Andrew J.H

“…Abstract The prophylactic potential of the azalide azithromycin as well as the fluoroquinolones trovafloxacin and grepafloxacin was assessed for the control of…”
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Efficacy of moxifloxacin or gatifloxacin as prophylaxis against experimental murine Brucella melitensis infection by Atkins, Helen S, Spencer, Stephen, Brew, Simon D, Laws, Thomas R, Thirlwall, Rachel E, MacMillan, Alastair P, Brooks, Timothy J.G, Simpson, Andrew J.H

“…Abstract The prophylactic potential of moxifloxacin and gatifloxacin was assessed in comparison with doxycycline, an established therapeutic antibiotic, to…”
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Evaluation of azithromycin, trovafloxacin and grepafloxacin as prophylaxis for experimental murine melioidosis by Kenny, Dermot J, Sefton, Armine M, Brooks, Timothy J.G, Laws, Thomas R, Simpson, Andrew J.H, Atkins, Helen S

“…Abstract The efficacies of the azalide azithromycin and the fluoroquinolones trovafloxacin and grepafloxacin for pre- and post-exposure prophylaxis of…”
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Presence and Persistence of Zika Virus RNA in Semen, United Kingdom, 2016 by Atkinson, Barry, Thorburn, Fiona, Petridou, Christina, Bailey, Daniel, Hewson, Roger, Simpson, Andrew J H, Brooks, Timothy J G, Aarons, Emma J

“…Zika virus RNA has been detected in semen collected several months after onset of symptoms of infection. Given the potential for sexual transmission of Zika…”
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Post-exposure prophylaxis of systemic anthrax in mice and treatment with fluoroquinolones by Steward, J., Lever, M. S., Simpson, A. J. H., Sefton, A. M., Brooks, T. J. G.

“…Objectives: To compare the fluoroquinolones gatifloxacin and moxifloxacin with ciprofloxacin for post-exposure prophylaxis of systemic anthrax in a BALB/c…”
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Ebola and other viral haemorrhagic fevers by Fletcher, Tom E, Brooks, Timothy J G, Beeching, Nicholas J

“…Be prepared, with new guidance featuring old and well established principles…”
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Imported rickettsial infections to the United Kingdom, 2015-2020 by Warrell, Clare E, Osborne, Jane, Nabarro, Laura, Gibney, Barry, Carter, Daniel P, Warner, Jennifer, Houlihan, Catherine F, Brooks, Timothy J G, Rampling, Tommy

“…The burden of imported rickettsial infection in the UK is not previously described. This retrospective review identifies rickettsial cases diagnosed at the…”
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Serological surveillance of SARS-CoV-2: Six-month trends and antibody response in a cohort of public health workers by Harris, Ross J., Whitaker, Heather J., Andrews, Nick J., Aiano, Felicity, Amin-Chowdhury, Zahin, Flood, Jessica, Borrow, Ray, Linley, Ezra, Ahmad, Shazaad, Stapley, Lorraine, Hallis, Bassam, Amirthalingam, Gayatri, Höschler, Katja, Parker, Ben, Horsley, Alex, Brooks, Timothy J.G., Brown, Kevin E., Ramsay, Mary E., Ladhani, Shamez N.

“…Antibody waning after SARS-CoV-2 infection may result in reduction in long-term immunity following natural infection and vaccination, and is therefore a major…”
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In vivo efficacy of fluoroquinolones against systemic tularaemia infection in mice by Piercy, T., Steward, J., Lever, M. S., Brooks, T. J. G.

“…Objectives: The in vivo efficacy of ciprofloxacin, gatifloxacin and moxifloxacin were assessed in an experimental Francisella tularensis Schu S4 infection in…”
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Infections in travellers returning to the UK: a retrospective analysis (2015–2020) by Warner, Jennifer C, Hatziioanou, Diane, Osborne, Jane C, Bailey, Daniel J, Brooks, Timothy J G, Semper, Amanda E

“…Abstract Background Every year, many thousands of travellers return to the United Kingdom (UK) from visits to other countries and some will become unwell due…”
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The future of enzymes in cosmetics by LODS, L. M, DRES, C, JOHNSON, C, SCHOLZ, D. B, BROOKS, G. J

“…Synopsis The skin employs a host of protective mechanisms to defend itself against the ravages of the environment. One of the most widely studied protective…”
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