Search Results - "Brooks, Donald E."

Antibacterial Surfaces Based on Polymer Brushes: Investigation on the Influence of Brush Properties on Antimicrobial Peptide Immobilization and Antimicrobial Activity by Gao, Guangzheng, Yu, Kai, Kindrachuk, Jason, Brooks, Donald E, Hancock, Robert E. W, Kizhakkedathu, Jayachandran N

“…Primary amine containing copolymer, poly­( N,N -dimethylacrylamide-co-N-(3-aminopropyl)­methacrylamide hydrochloride) (poly­(DMA-co-APMA)), brushes were…”
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In vivo biological evaluation of high molecular weight hyperbranched polyglycerols by Kainthan, Rajesh K, Brooks, Donald E

“…Abstract Hyperbranched polyglycerols (HPGs) are water-soluble polyether polyols that can be synthesized in a controlled manner with low polydispersity…”
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A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment by Yu, Xifei, Yang, Xiaoqiang, Horte, Sonja, Kizhakkedathu, Jayachandran N, Brooks, Donald E

“…Abstract Solid tumors generally exhibit an acidic microenvironment which has been recognized as a potential route to distinguishing tumor from normal tissue…”
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Choline phosphate functionalized cellulose membrane: A potential hemostatic dressing based on a unique bioadhesion mechanism by Yang, Xiaoqiang, Li, Na, Constantinesco, Iren, Yu, Kai, Kizhakkedathu, Jayachandran N., Brooks, Donald E.

“…[Display omitted] Wound dressings are a key component in provision of optimal conditions for bleeding control and wound healing. For absorbent dressings,…”
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Synthesis, Characterization, and Viscoelastic Properties of High Molecular Weight Hyperbranched Polyglycerols by Kainthan, Rajesh Kumar, Muliawan, Edward B, Hatzikiriakos, Savvas G, Brooks, Donald E

“…Very high molecular weight (M n up to 700 000) and narrowly polydispersed (PDI = 1.1−1.4) hyperbranched polyglycerols (HPG) were synthesized by ring-opening…”
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Biocompatibility Testing of Branched and Linear Polyglycidol by Kainthan, Rajesh Kumar, Janzen, Johan, Levin, Elena, Devine, Dana V, Brooks, Donald E

“…Polyglycidols are flexible hydrophilic polyethers that are potentially biocompatible polymers based on their similarities to the well-studied…”
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Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants by Shenoi, Rajesh A, Kalathottukaren, Manu Thomas, Travers, Richard J, Lai, Benjamin F L, Creagh, A Louise, Lange, Dirk, Yu, Kai, Weinhart, Marie, Chew, Ben H, Du, Caigan, Brooks, Donald E, Carter, Cedric J, Morrissey, James H, Haynes, Charles A, Kizhakkedathu, Jayachandran N

“…Heparin-based anticoagulant drugs have been widely used for the prevention of blood clotting during surgical procedures and for the treatment of thromboembolic…”
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Unimolecular Micelles Based On Hydrophobically Derivatized Hyperbranched Polyglycerols: Ligand Binding Properties by Kainthan, Rajesh Kumar, Mugabe, Clement, Burt, Helen M, Brooks, Donald E

“…This paper discusses the binding and release properties of hydrophobically modified hyperbranched polyglycerol−polyethylene glycol copolymers that were…”
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ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive by Yu, Xifei, Yang, Xiaoqiang, Horte, Sonja, Kizhakkedathu, Jayachandran N, Brooks, Donald E

“…A new monomer, 2-(methacryloyloxy)ethyl choline phosphate, and its direct polymerization into a polyvalent choline phosphate are described, providing a…”
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Surface Modification of Polyvinyl Chloride Sheets via Growth of Hydrophilic Polymer Brushes by Zou, Yuquan, Kizhakkedathu, Jayachandran N, Brooks, Donald E

“…Poly(N,N-dimethylacrylamide) (PDMA) brushes were successfully grown from polyvinyl chloride (uPVC) sheets via well-controlled surface-initiated atom transfer…”
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Synthesis and Characterization of Carboxylic Acid Conjugated, Hydrophobically Derivatized, Hyperbranched Polyglycerols as Nanoparticulate Drug Carriers for Cisplatin by Ye, Lucy, Letchford, Kevin, Heller, Markus, Liggins, Richard, Guan, Dechi, Kizhakkedathu, Jayachandran N, Brooks, Donald E, Jackson, John K, Burt, Helen M

“…Hyperbranched polyglycerols (HPGs) with hydrophobic cores and derivatized with methoxy poly(ethylene glycol) were synthesized and further functionalized with…”
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Hyperbranched polyglycerol as a colloid in cold organ preservation solutions by Gao, Sihai, Guan, Qiunong, Chafeeva, Irina, Brooks, Donald E, Nguan, Christopher Y C, Kizhakkedathu, Jayachandran N, Du, Caigan

“…Hydroxyethyl starch (HES) is a common colloid in organ preservation solutions, such as in University of Wisconsin (UW) solution, for preventing graft…”
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Synthesis of Well-Defined Environmentally Responsive Polymer Brushes by Aqueous ATRP by Kizhakkedathu, Jayachandran N, Norris-Jones, Raymond, Brooks, Donald E

“…Functionalized anionic polystyrene latex particles with ATRP initiators were synthesized by surfactant-free shell-growth emulsion polymerization of styrene and…”
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Preclinical PET Imaging and Toxicity Study of a 68Ga-Functionalized Polymeric Cardiac Blood Pool Agent by Saatchi, Katayoun, Bénard, François, Hundal, Navjit, Grimes, Joshua, Shcherbinin, Sergey, Pourghiasian, Maral, Brooks, Donald E., Celler, Anna, Häfeli, Urs O.

“…Cardiac blood pool imaging is currently performed almost exclusively with 99mTc-based compounds and SPECT/CT imaging. Using a generator-based PET radioisotope…”
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Thermal Reversal of Polyvalent Choline Phosphate, a Multivalent Universal Biomembrane Adhesive by Yu, Xifei, Zou, Yuquan, Horte, Sonja, Janzen, Johan, Kizhakkedathu, Jayachandran N, Brooks, Donald E

“…Multivalent macromolecular associations are widely observed in biological systems and are increasingly being utilized in bioengineering, nanomedicine, and…”
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Poly(oligo(ethylene glycol)acrylamide) Brushes by Surface Initiated Polymerization: Effect of Macromonomer Chain Length on Brush Growth and Protein Adsorption from Blood Plasma by Kizhakkedathu, Jayachandran N, Janzen, Johan, Le, Yevgeniya, Kainthan, Rajesh K, Brooks, Donald E

“…Three hydrolytically stable polyethyleneglycol (PEG)-based N-substituted acrylamide macromonomers, methoxypolyethyleneglycol (350) acrylamide (MPEG350Am)…”
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Size-Dependant Cellular Uptake of Dendritic Polyglycerol by Reichert, Stephanie, Welker, Pia, Calderón, Marcelo, Khandare, Jayant, Mangoldt, Dorothea, Licha, Kai, Kainthan, Rajesh K., Brooks, Donald E., Haag, Rainer

“…To study the mechanism of cellular internalization, hyperbranched polyether derivatives consisting of amino‐bearing hyperbranched polyglycerols (HPGs) of…”
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Hydrophobically derivatized hyperbranched polyglycerol as a human serum albumin substitute by Kainthan, Rajesh K, Janzen, Johan, Kizhakkedathu, Jayachandran N, Devine, Dana V, Brooks, Donald E

“…Abstract There is a huge clinical demand for Human Serum Albumin (HSA), with a world market of ∼$1.5B/year. Concern over prion and viral transmission in the…”
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The induction of thrombus generation on nanostructured neutral polymer brush surfaces by Lai, Benjamin F.L, Creagh, A. Louise, Janzen, Johan, Haynes, Charles A, Brooks, Donald E, Kizhakkedathu, Jayachandran N

“…Abstract Surface induced thrombus generation is a major clinical concern associated with vascular medical devices and implants. Here, we show that high graft…”
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Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol by Wen, Jiying, Weinhart, Marie, Lai, Benjamin, Kizhakkedathu, Jayachandran, Brooks, Donald E

“…Abstract A library of hyperbranched polyglycerols (HPGs) functionalized with different mole fractions of zwitterionic sulfabetaine and cationic quaternary…”
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