Search Results - "Brookes, Sara T"

The COMET Handbook: version 1.0 by Williamson, Paula R, Altman, Douglas G, Bagley, Heather, Barnes, Karen L, Blazeby, Jane M, Brookes, Sara T, Clarke, Mike, Gargon, Elizabeth, Gorst, Sarah, Harman, Nicola, Kirkham, Jamie J, McNair, Angus, Prinsen, Cecilia A C, Schmitt, Jochen, Terwee, Caroline B, Young, Bridget

“…The selection of appropriate outcomes is crucial when designing clinical trials in order to compare the effects of different interventions directly. For the…”
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A systematic review of core outcome set development studies demonstrates difficulties in defining unique outcomes by Young, Amber E, Brookes, Sara T, Avery, Kerry N.L, Davies, Anna, Metcalfe, Chris, Blazeby, Jane M

“…AbstractObjectivesCore outcome set (COS) development often begins with a systematic review to identify outcomes. Reviews frequently show heterogeneity in…”
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Core Outcomes for Colorectal Cancer Surgery: A Consensus Study by McNair, Angus G K, Whistance, Robert N, Forsythe, Rachael O, Macefield, Rhiannon, Rees, Jonathan, Pullyblank, Anne M, Avery, Kerry N L, Brookes, Sara T, Thomas, Michael G, Sylvester, Paul A, Russell, Ann, Oliver, Alfred, Morton, Dion, Kennedy, Robin, Jayne, David G, Huxtable, Richard, Hackett, Roland, Dutton, Susan J, Coleman, Mark G, Card, Mia, Brown, Julia, Blazeby, Jane M

“…Colorectal cancer (CRC) is a major cause of worldwide morbidity and mortality. Surgical treatment is common, and there is a great need to improve the delivery…”
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A Core Outcome Set for the Benefits and Adverse Events of Bariatric and Metabolic Surgery: The BARIACT Project by Coulman, Karen D, Hopkins, James, Brookes, Sara T, Chalmers, Katy, Main, Barry, Owen-Smith, Amanda, Andrews, Robert C, Byrne, James, Donovan, Jenny L, Mazza, Graziella, Reeves, Barnaby C, Rogers, Chris A, Thompson, Janice L, Welbourn, Richard, Wordsworth, Sarah, Blazeby, Jane M

“…Bariatric and metabolic surgery is used as a treatment for patients with severe and complex obesity. However, there is a need to improve outcome selection and…”
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Thulium laser transurethral vaporesection versus transurethral resection of the prostate for benign prostatic obstruction: the UNBLOCS RCT by Worthington, Jo, Lane, J Athene, Taylor, Hilary, Young, Grace, Noble, Sian M, Abrams, Paul, Ahern, Aideen, Brookes, Sara T, Cotterill, Nikki, Johnson, Lyndsey, Khan, Rafiyah, Fernandez, Aida Moure, Page, Tobias, Swami, Satchi, Hashim, Hashim

“…Transurethral resection of the prostate (TURP) is the standard operation for benign prostatic obstruction (BPO). Thulium laser transurethral vaporesection of…”
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A review of reporting of participant recruitment and retention in RCTs in six major journals by Toerien, Merran, Brookes, Sara T, Metcalfe, Chris, de Salis, Isabel, Tomlin, Zelda, Peters, Tim J, Sterne, Jonathan, Donovan, Jenny L

“…Poor recruitment and retention of participants in randomised controlled trials (RCTs) is problematic but common. Clear and detailed reporting of participant…”
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Impact of question order on prioritisation of outcomes in the development of a core outcome set: a randomised controlled trial by Brookes, Sara T, Chalmers, Katy A, Avery, Kerry N L, Coulman, Karen, Blazeby, Jane M

“…Core outcome set (COS) developers increasingly employ Delphi surveys to elicit stakeholders' opinions of which outcomes to measure and report in trials of a…”
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'Trial Exegesis': Methods for Synthesizing Clinical and Patient Reported Outcome (PRO) Data in Trials to Inform Clinical Practice. A Systematic Review by McNair, Angus G K, Macefield, Rhiannon C, Blencowe, Natalie S, Brookes, Sara T, Blazeby, Jane M

“…The CONSORT extension for patient reported outcomes (PROs) aims to improve reporting, but guidance on the optimal integration with clinical data is lacking…”
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A randomised controlled trial to determine the clinical and cost effectiveness of thulium laser transurethral vaporesection of the prostate (ThuVARP) versus transurethral resection of the prostate (TURP) in the National Health Service (NHS) - the UNBLOCS trial: a study protocol for a randomised controlled trial by Worthington, Jo, Taylor, Hilary, Abrams, Paul, Brookes, Sara T, Cotterill, Nikki, Noble, Sian M, Page, Tobias, Swami, K Satchi, Lane, J Athene, Hashim, Hashim

“…Transurethral resection of the prostate (TURP) has been the standard operation for benign prostatic obstruction (BPO) for 40 years, with approximately 25,000…”
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Communicating the Results of Randomized Clinical Trials: Do Patients Understand Multidimensional Patient-Reported Outcomes? by MCNAIR, Angus G. K, BROOKES, Sara T, DAVIS, Christopher R, ARGYROPOULOS, Miltiadis, BLAZEBY, Jane M

“…PURPOSE Evidence suggests that patient-reported outcomes (PROs) from randomized trials in oncology may not influence clinical decision making and patient…”
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Standards of Outcome Reporting in Surgical Oncology: A Case Study in Esophageal Cancer by Blencowe, Natalie S., McNair, Angus G. K., Davis, Christopher R., Brookes, Sara T., Blazeby, Jane M.

“…Background Multimodal strategies before surgery are often used to improve outcomes, but disease progression (precluding surgical resection) and inoperability…”
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Reporting of Short-Term Clinical Outcomes After Esophagectomy: A Systematic Review by BLENCOWE, Natalie S, STRONG, Sean, MCNAIR, Angus G. K, BROOKES, Sara T, CROSBY, Tom, MICHAEL GRIFFIN, S, BLAZEBY, Jane M

“…This review summarizes reporting of complications of esophageal cancer surgery. Accurate assessment of morbidity and mortality after surgery for cancer is…”
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Development of a Core Outcome Set for Clinical Effectiveness Trials in Esophageal Cancer Resection Surgery by Avery, Kerry N L, Chalmers, Katy A, Brookes, Sara T, Blencowe, Natalie S, Coulman, Karen, Whale, Katie, Metcalfe, Chris, Blazeby, Jane M

“…OBJECTIVE:Development of a core outcome set (COS) for clinical effectiveness trials in esophageal cancer resection surgery. BACKGROUND:Inconsistency and…”
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Controversy and Debate Series on Core Outcome Sets. Paper 4: Debate on Paper 1 from the perspective of COMET [Core Outcome Measures in Effectiveness Trials] by Williamson, Paula R., Blazeby, Jane M., Brookes, Sara T., Clarke, Mike, Terwee, Caroline B., Young, Bridget

“…•These comments are provided by authors of the COMET Handbook: The COMET Handbook: version 1.0 (2017) Williamson PR, Altman DG, Bagley H, Barnes KL, Blazeby…”
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Core Items for a Standardized Resource Use Measure: Expert Delphi Consensus Survey by Thorn, Joanna C., Brookes, Sara T., Ridyard, Colin, Riley, Ruth, Hughes, Dyfrig A., Wordsworth, Sarah, Noble, Sian M., Thornton, Gail, Hollingworth, William

“…Resource use measurement by patient recall is characterized by inconsistent methods and a lack of validation. A validated standardized resource use measure…”
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Three nested randomized controlled trials of peer-only or multiple stakeholder group feedback within Delphi surveys during core outcome and information set development by Brookes, Sara T, Macefield, Rhiannon C, Williamson, Paula R, McNair, Angus G, Potter, Shelley, Blencowe, Natalie S, Strong, Sean, Blazeby, Jane M

“…Methods for developing a core outcome or information set require involvement of key stakeholders to prioritise many items and achieve agreement as to the core…”
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Content of Health Economics Analysis Plans (HEAPs) for Trial-Based Economic Evaluations: Expert Delphi Consensus Survey by Thorn, Joanna C., Davies, Charlotte F., Brookes, Sara T., Noble, Sian M., Dritsaki, Melina, Gray, Ewan, Hughes, Dyfrig A., Mihaylova, Borislava, Petrou, Stavros, Ridyard, Colin, Sach, Tracey, Wilson, Edward C.F., Wordsworth, Sarah, Hollingworth, William

“…Health economics analysis plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential…”
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Suicide rates in young men in England and Wales in the 21st century: time trend study by Biddle, Lucy, Brock, Anita, Brookes, Sara T, Gunnell, David

“…Objectives To explore trends in suicide in young people to investigate the recent observation that after year on year rises in the 1970s, 1980s, and early…”
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Effect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection: A Randomized Clinical Trial by Hay, Alastair D, Little, Paul, Harnden, Anthony, Thompson, Matthew, Wang, Kay, Kendrick, Denise, Orton, Elizabeth, Brookes, Sara T, Young, Grace J, May, Margaret, Hollinghurst, Sandra, Carroll, Fran E, Downing, Harriet, Timmins, David, Lafond, Natasher, El-Gohary, Magdy, Moore, Michael

“…IMPORTANCE: Acute lower respiratory tract infection is common and often treated inappropriately in primary care with antibiotics. Corticosteroids are…”
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Developing core outcomes sets: methods for identifying and including patient-reported outcomes (PROs) by Macefield, Rhiannon C, Jacobs, Marc, Korfage, Ida J, Nicklin, Joanna, Whistance, Robert N, Brookes, Sara T, Sprangers, Mirjam A G, Blazeby, Jane M

“…Synthesis of patient-reported outcome (PRO) data is hindered by the range of available PRO measures (PROMs) composed of multiple scales and single items with…”
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