Search Results - "Brookes, Noah"

Regulation of ERK2 activity by dynamic S-acylation by Azizi, Saara-Anne, Qiu, Tian, Brookes, Noah E., Dickinson, Bryan C.

“…Extracellular signal-regulated kinases (ERK1/2) are key effector proteins of the mitogen-activated protein kinase pathway, choreographing essential processes…”
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A High-Throughput Fluorescent Turn-On Assay for Inhibitors of DHHC Family Proteins by Qiu, Tian, Azizi, Saara-Anne, Brookes, Noah, Lan, Tong, Dickinson, Bryan C.

“…As the “writer” enzymes of protein S-acylation, a dynamic and functionally significant post-translational modification (PTM), DHHC family proteins have emerged…”
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Development of an Acrylamide-Based Inhibitor of Protein S‑Acylation by Azizi, Saara-Anne, Lan, Tong, Delalande, Clémence, Kathayat, Rahul S, Banales Mejia, Fernando, Qin, Alice, Brookes, Noah, Sandoval, Perla Jasmine, Dickinson, Bryan C

“…Protein S-acylation is a dynamic lipid post-translational modification that can modulate the localization and activity of target proteins. In humans, the…”
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