Search Results - "Brooke, Allison C."

The effects of the TRPV1 antagonist SB-705498 on TRPV1 receptor-mediated activity and inflammatory hyperalgesia in humans by Chizh, Boris A., O’Donnell, Mary B., Napolitano, Antonella, Wang, Jie, Brooke, Allison C., Aylott, Mike C., Bullman, Jonathan N., Gray, Emily J., Lai, Robert Y., Williams, Pauline M., Appleby, Jonathan M.

“…TRPV1 is a cation channel activated by a range of noxious stimuli and highly expressed in nociceptive fibres. TRPV1 receptors are involved in pain and…”
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Opioid Receptor Modulation of Hedonic Taste Preference and Food Intake: A Single-Dose Safety, Pharmacokinetic, and Pharmacodynamic Investigation With GSK1521498, a Novel μ-Opioid Receptor Inverse Agonist by Nathan, Pradeep J., O'Neill, Barry V., Bush, Mark A., Koch, Annelize, Tao, Wenli X., Maltby, Kay, Napolitano, Antonella, Brooke, Allison C., Skeggs, Andrew L., Herman, Craig S., Larkin, Andrew L., Ignar, Diane M., Richards, Duncan B., Williams, Pauline M., Bullmore, Edward T.

“…Endogenous opioids and µ-opioid receptors have been linked to hedonic and rewarding aspects of palatable food intake. The authors examined the safety,…”
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Multiple-Dose Safety, Pharmacokinetics, and Pharmacodynamics of the μ-Opioid Receptor Inverse Agonist GSK1521498 by Nathan, Pradeep J., Bush, Mark A., Tao, Wenli X., Koch, Annelize, Davies, Kirsty M., Maltby, Kay, O'Neill, Barry V., Napolitano, Antonella, Skeggs, Andrew L., Brooke, Allison C., Richards, Duncan B., Williams, Pauline M., Bullmore, Edward T.

“…The endogenous opioid system and µ-opioid receptors in particular have been demonstrated to play a fundamental role in hedonic and motivational behaviors…”
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