Search Results - "Brook, J G"
-
1
Obesity is the major determinant of elevated C-reactive protein in subjects with the metabolic syndrome
Published in International Journal of Obesity (01-05-2004)“…To investigate the relationship between C-reactive protein (CRP) and various characteristics of the metabolic syndrome. Population-based cross-sectional study…”
Get full text
Journal Article -
2
Association between fasting glucose and C-reactive protein in middle-aged subjects
Published in Diabetic medicine (01-01-2004)“…Aims C‐reactive protein (CRP), a marker of subclinical inflammation, predicts the occurrence of coronary heart disease in healthy subjects. Hyperglycaemia is…”
Get full text
Journal Article -
3
Pravastatin inhibits cellular cholesterol synthesis and increases low density lipoprotein receptor activity in macrophages: in vitro and in vivo studies
Published in British journal of clinical pharmacology (01-12-1994)“…1. Pravastatin, a 3‐hydroxy‐3‐methylglutaryl coenzyme‐A (HMG‐CoA) inhibitor, is a highly selective inhibitor of hepatic cholesterol synthesis. We studied the…”
Get full text
Journal Article -
4
Association Between Elevated Liver Enzymes and C-Reactive Protein: Possible Hepatic Contribution to Systemic Inflammation in the Metabolic Syndrome
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2005)“…OBJECTIVE—The objective of this study was to test whether the frequent association between liver enzyme elevations and various components of the metabolic…”
Get full text
Journal Article -
5
Low density lipoprotein isolated from patients with essential hypertension exhibits increased propensity for oxidation and enhanced uptake by macrophages: a possible role for angiotensin II
Published in Atherosclerosis (01-05-1994)“…In patients with essential hypertension, the increased risk for atherosclerosis is related not only to the blood pressure levels per se, but also to other,…”
Get more information
Journal Article -
6
Lovastatin decreases plasma and platelet cholesterol levels and normalizes elevated platelet fluidity and aggregation in hypercholesterolemic patients
Published in Metabolism, clinical and experimental (01-01-1994)“…The lipid composition of whole platelets and the fluidity of platelet membranes, as well as the sensitivity of the cell to aggregation, were studied in type…”
Get more information
Journal Article -
7
The D allele of the angiotensin-converting enzyme gene contributes towards blood LDL-cholesterol levels and the presence of hypertension
Published in Atherosclerosis (01-08-1999)“…Coronary artery disease is a polygenic disease whose phenotypic manifestation depends on the interaction of the genetic background with a number of…”
Get full text
Journal Article Conference Proceeding -
8
Activated platelets secrete a protein-like factor that stimulates oxidized-LDL receptor activity in macrophages
Published in Journal of lipid research (01-07-1991)“…Platelet secretory products were shown to modulate the interaction between lipoproteins and their receptors on macrophages. Preincubation of macrophages for 2…”
Get full text
Journal Article -
9
Reduction of plasma cholesterol by lovastatin normalizes erythrocyte membrane fluidity in patients with severe hypercholesterolaemia
Published in British journal of clinical pharmacology (01-11-1992)“…The effect of lovastatin on erythrocyte membrane composition and fluidity was investigated in eight patients with severe hypercholesterolaemia (mean…”
Get full text
Journal Article -
10
Rhabdomyolysis complicating acute Epstein-Barr virus infection
Published in Infection (01-03-1995)“…Infection with Epstein-Barr virus (EBV) is common and induces a broad spectrum of illness. In the majority of cases the disease manifests with typical signs of…”
Get full text
Journal Article -
11
Platelet activation by plasma lipoproteins
Published in Progress in cardiovascular diseases (01-07-1987)“…Enhanced platelet activity in patients with hypercholesterolemia and moderate hypertriglyceridemia can be attributed to increased LDL and VLDL and/or decreased…”
Get more information
Journal Article -
12
Reduced uptake of cholesterol esterase-modified low density lipoprotein by macrophages
Published in The Journal of biological chemistry (25-06-1991)“…Changes in low density lipoprotein (LDL) lipid composition were shown to alter its interaction with the LDL receptor, thus affecting its cellular uptake. Upon…”
Get full text
Journal Article -
13
Serum total cholesterol: HDL cholesterol ratios in US white and black adults by selected demographic and socioeconomic variables (HANES II)
Published in American journal of public health (1971) (01-08-1991)“…Background. Framingham Study findings suggest that total cholesterol (TC):High density lipoprotein cholesterol (HDL-C) ratio is a useful summary of the joint…”
Get full text
Journal Article -
14
Abdominal retroperitoneal lymphadenopathy in an elderly man
Published in Postgraduate medical journal (01-09-1997)Get full text
Journal Article -
15
Pulmonary infiltrates and skin lesions
Published in Postgraduate medical journal (01-04-1997)Get full text
Journal Article -
16
Transient radiological and colonoscopic features of inflammatory bowel disease in a patient with severe Salmonella gastroenteritis
Published in The American journal of gastroenterology (01-02-1997)“…Salmonella is the most commonly reported cause of food-borne outbreaks of gastroenteritis. We report a case of a severe and toxic form of enteritis caused by…”
Get more information
Journal Article -
17
Cholesterol and coronary heart disease prevention--a transatlantic consensus
Published in European heart journal (01-08-1989)“…Recent research findings have enhanced interest in coronary heart disease prevention. Three expert panels, one in the United States and two in Europe, have…”
Get more information
Journal Article -
18
Plasma lipoproteins and monocyte‐macrophages in a peroxisome‐deficient system: Study of a patient with infantile refsum disease
Published in Journal of inherited metabolic disease (01-09-1992)“…Summary Hypocholesterolaemia in infantile Refsum disease (IRD) may link peroxisomes and lipoprotein metabolism. In our patient, plasma cholesterol levels were…”
Get full text
Journal Article -
19
Sudden deafness in a patient with temporal arteritis
Published in Journal of rheumatology (01-04-1987)“…A patient with anemia and elevated erythrocyte sedimentation rate presented with sudden hearing loss. The diagnosis of temporal arteritis was verified by…”
Get more information
Journal Article -
20
Intralipid infusion in patients with familial hypercholesterolemia. Effect of serum and plasma lipoproteins on platelet aggregation and on macrophage cholesterol metabolism
Published in Atherosclerosis (01-02-1990)“…Intralipid infusion into normal volunteers was recently shown to possess anti-atherogenic properties. We studied the effect of intralipid infusion in patients…”
Get more information
Journal Article