Search Results - "Bromberg, Y."

Building a Genome Analysis Pipeline to Predict Disease Risk and Prevent Disease by Bromberg, Y.

“…Reduced costs and increased speed and accuracy of sequencing can bring the genome-based evaluation of individual disease risk to the bedside. While past…”
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Deep learning of a bacterial and archaeal universal language of life enables transfer learning and illuminates microbial dark matter by Hoarfrost, A., Aptekmann, A., Farfañuk, G., Bromberg, Y.

“…The majority of microbial genomes have yet to be cultured, and most proteins identified in microbial genomes or environmental sequences cannot be functionally…”
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SNAP: predict effect of non-synonymous polymorphisms on function by Bromberg, Yana, Rost, Burkhard

“…Many genetic variations are single nucleotide polymorphisms (SNPs). Non-synonymous SNPs are 'neutral' if the resulting point-mutated protein is not…”
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mebipred: identifying metal-binding potential in protein sequence by Aptekmann, A A, Buongiorno, J, Giovannelli, D, Glamoclija, M, Ferreiro, D U, Bromberg, Y

“…Abstract Motivation metal-binding proteins have a central role in maintaining life processes. Nearly one-third of known protein structures contain metal ions…”
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Computational predictors fail to identify amino acid substitution effects at rheostat positions by Miller, M., Bromberg, Y., Swint-Kruse, L.

“…Many computational approaches exist for predicting the effects of amino acid substitutions. Here, we considered whether the protein sequence position class –…”
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Hanbury Brown and Twiss interferometry with interacting photons by Bromberg, Y, Silberberg, Y, Lahini, Y, Small, E

“…Five decades ago, Hanbury Brown and Twiss (HBT) demonstrated that the angular size of stars can be measured by correlating the intensity fluctuations measured…”
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Critical states embedded in the continuum by Koirala, M, Yamilov, A, Basiri, A, Bromberg, Y, Cao, H, Kottos, T

“…We introduce a class of critical states which are embedded in the continuum (CSC) of a one-dimensional optical waveguide array with one non-Hermitian defect…”
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Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case–control study by Calton, Melissa A., Ersoy, Baran A., Zhang, Sumei, Kane, John P., Malloy, Mary J., Pullinger, Clive R., Bromberg, Yana, Pennacchio, Len A., Dent, Robert, McPherson, Ruth, Ahituv, Nadav, Vaisse, Christian

“…Functionally significant heterozygous mutations in the Melanocortin-4 receptor (MC4R) have been implicated in 2.5% of early onset obesity cases in European…”
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Full-field optical coherence microscopy is a novel technique for imaging enteric ganglia in the gastrointestinal tract by Coron, E., Auksorius, E., Pieretti, A., Mahé, M. M., Liu, L., Steiger, C., Bromberg, Y., Bouma, B., Tearney, G., Neunlist, M., Goldstein, A. M.

“…Background  Noninvasive methods are needed to improve the diagnosis of enteric neuropathies. Full‐field optical coherence microscopy (FFOCM) is a novel optical…”
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Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate by Bromberg, Y, Pick, E

“…Sodium dodecyl sulfate (SDS) elicits the production of superoxide (O2-) by a cell-free system represented by sonically disrupted guinea pig peritoneal…”
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The Neuroprotective Adenosine-Activated Signal Transduction Pathway Involves Activation of Phospholipase C by Rogel, A., Bromberg, Y., Sperling, O., Zoref-Shani, E.

“…We have demonstrated before that exposure of neuronal cultures to poisoning by iodoacetic acid (IAA) followed by "reperfusion" (IAA-R insult), results in…”
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The GDP-bound form of the small G protein Rac1 p21 is a potent activator of the superoxide-forming NADPH oxidase of macrophages by BROMBERG, Y, SHANI, E, JOSEPH, G, GORZALCZANY, Y, SPERLING, O, PICK, E

“…Phagocytes produce superoxide by the assembly of a multicomponent complex that utilizes NADPH for the reduction of molecular oxygen (NADPH oxidase). The…”
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Clinical and Biochemical Manifestations and Molecular Characterization of the Mutation HPRT Jerusalem by Zoref-Shani, E., Bromberg, Y., Hirsch, J., Feinstein, S., Frishberg, Y., Sperling, O.

“…A novel point mutation (I137T) was identified in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) encoding gene, in a patient with partial deficiency…”
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Activation of the superoxide forming NADPH oxidase in a cell-free system by sodium dodecyl sulfate. Characterization of the membrane-associated component by Pick, E, Bromberg, Y, Shpungin, S, Gadba, R

“…Sodium dodecyl sulfate (SDS) was shown to elicit NADPH-dependent superoxide (O2-) production by a cell-free system derived from sonically disrupted resting…”
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Bioinformatics for personal genome interpretation by Capriotti, Emidio, Nehrt, Nathan L, Kann, Maricel G, Bromberg, Yana

“…An international consortium released the first draft sequence of the human genome 10 years ago. Although the analysis of this data has suggested the genetic…”
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Light localization induced by a random imaginary refractive index by Basiri, A., Bromberg, Y., Yamilov, A., Cao, H., Kottos, T.

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Developmental changes in purine nucleotide metabolism in cultured rat astroglia by Zoref-Shani, E, Bromberg, Y, Lilling, G, Gozes, I, Brosh, S, Sidi, Y, Sperling, O

“…The present study was conducted in order to clarify the role of the glia in brain purine metabolism. This, in connection with the clarification of the etiology…”
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Close-packed floating clusters: granular hydrodynamics beyond the freezing point? by Meerson, Baruch, Pöschel, Thorsten, Bromberg, Yaron

“…Monodisperse granular flows often develop regions with hexagonal close packing of particles. We investigate this effect in a system of inelastic hard spheres…”
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Purine nucleotide metabolism in cultured neurons and astroglia from HPRT-deficient knockout mice by Zoref-Shani, E, Boer, P, Brosh, S, Pelled, D, Bromberg, Y, Sperling, O

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Starlink: Runtime Interoperability between Heterogeneous Middleware Protocols by Bromberg, Y., Grace, P., Réveillère, L.

“…Interoperability remains a challenging and growing problem within distributed systems. A range of heterogeneous network and middleware protocols which cannot…”
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