Search Results - "Bromberg, J.S."

Human Microbiota Characterization in the Course of Renal Transplantation by Fricke, W. F., Maddox, C., Song, Y., Bromberg, J. S.

“…Recent studies demonstrate that the human microbiota, the collection of microorganisms growing on and in individuals, have numerous bidirectional interactions…”
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New Cellular and Molecular Immune Pathways in Ischemia/Reperfusion Injury by Boros, P., Bromberg, J. S.

“…Ischemia/reperfusion injury (IRI) is a multi‐factorial antigen‐independent inflammatory condition that profoundly affects both early and long‐term function of…”
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Immune Reconstitution Following Rabbit Antithymocyte Globulin by Gurkan, S., Luan, Y., Dhillon, N., Allam, S. R., Montague, T., Bromberg, J. S., Ames, S., Lerner, S., Ebcioglu, Z., Nair, V., Dinavahi, R., Sehgal, V., Heeger, P., Schroppel, B., Murphy, B.

“…Depletional induction therapies are routinely used to prevent acute rejection and improve transplant outcome. The effects of depleting agents on T‐cell subsets…”
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Inhibition of TLR4 signaling prolongs Treg-dependent murine islet allograft survival by Zhang, N, Krüger, B, Lal, G, Luan, Y, Yadav, A, Zang, W, Grimm, M, Waaga-Gasser, A.M, Murphy, B, Bromberg, J.S, Schröppel, B

“…Abstract Toll-like receptors (TLRs) provide an important link between innate and adaptive immune system. We hypothesized that the recognition of endogenous…”
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Direct versus Indirect Allorecognition: Visualization of Dendritic Cell Distribution and Interactions During Rejection and Tolerization by Ochando, J. C., Krieger, N. R., Bromberg, J. S.

“…Interactions of donor and recipient dendritic cells (DCs) with CD4+ T cells determine the alloantigenic response in organ transplantation, where recipient T…”
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Calcineurin-Inhibitor-Free Immunosuppression Based on the JAK Inhibitor CP-690,550: A Pilot Study in De Novo Kidney Allograft Recipients by BUSQUE, S, LEVENTHAL, J, SLAKEY, D, PEDDI, V. R, FISHER, R. A, LAWENDY, N, WANG, C, CHAN, G, BRENNAN, D. C, STEINBERG, S, KLINTMALM, G, SHAH, T, MULGAONKAR, S, BROMBERG, J. S, VINCENTI, F, HARIHARAN, S

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Innate Alloimmunity. Part 2: Innate Immunity and Allograft Rejection by Walter Gottlieb Land, Pabst Science Publishers, 2011 by Bromberg, J.S.

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What's Hot, What's New at WTC—Basic Science by Bromberg, J. S.

“…The World Transplant Congress of 2014 presented a broad swath of science that touched on many disparate aspects of cell and organ transplantation, molecular…”
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Natural Killer Cells and the Immune Response in Solid Organ Transplantation by Van Der Touw, W., Bromberg, J. S.

“…Natural killer (NK) cells have been characterized classically for their cytotoxicity against pathogen infected or stressed cells as well as for their role in…”
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Lymphotoxin‐Beta Receptor Blockade Induces Inflammation and Fibrosis in Tolerized Cardiac Allografts by Nakayama, Y., Bromberg, J. S.

“…The lymphotoxin system (LT) regulates interactions between lymphocytes and stromal cells to maintain lymphoid microenvironmental homeostasis. Soluble LT…”
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Fates of CD4+ T Cells in a Tolerant Environment Depend on Timing and Place of Antigen Exposure by Burrell, B. E., Bromberg, J. S.

“…In experimental organ transplantation, tolerance is induced by administration of anti‐CD40L mAb in conjunction with donor‐specific splenocyte transfusion…”
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Silk fibroin preserves beta cell function under inflammatory stress while stimulating islet cell surface GLUT2 expression by Ashari, N., Pang, H.W., Simon, T., Xiong, Y., Coburn, J.M., Bromberg, J.S., Kaplan, D.L., McLenithan, J., Fontaine, M.J.

“…•Silk is a novel biomaterial for islet cell delivery in vivo to treat diabetes.•Islet cell-function post transplantation is challenged by an inflammatory…”
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The ‘Two, One, Zero’ Decision: What to Do with Suboptimal Deceased Donor Kidneys by Shapiro, R., Halloran, P. F., Delmonico, F. L., Bromberg, J. S.

“…While it is feasible to transplant two ECD kidneys into a single recipient, we need better data to help us decide with confidence whether a given set of…”
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Human FOXP3+ Regulatory T Cells in Transplantation by Boros, P., Bromberg, J. S.

“…CD4+CD25+FOXP3+ suppressive regulatory T cells (Treg) represent a subset of immune regulatory cells. Based on experimental results, Treg have recently been…”
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Distinct Inflammatory Signals Have Physiologically Divergent Effects on Epigenetic Regulation of Foxp3 Expression and Treg Function by Lal, G., Yin, N., Xu, J., Lin, M., Schroppel, S., Ding, Y., Marie, I., Levy, D. E., Bromberg, J. S.

“…Foxp3 expression in regulatory T cells (Treg) is required for their development and suppressive function. How different inflammatory signals affect Foxp3…”
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Favorable Long‐Term Outcome after Liver‐Kidney Transplant for Recurrent Hemolytic Uremic Syndrome Associated with a Factor H Mutation by Saland, J. M., Emre, S. H., Shneider, B. L., Benchimol, C., Ames, S., Bromberg, J. S., Remuzzi, G., Strain, L., Goodship, T. H. J.

“…A male child initially presented with atypical hemolytic uremic syndrome (HUS) at the age of 4 months and progressed within weeks to end stage renal disease…”
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Is the Time Ripe for Genomic Diagnosis and Prediction of Rejection? by Bromberg, J. S., Iklé, D.

“…Citing the novel evidence and analyses of Li et al (page 2710) regarding genomic tools for the diagnosis of renal allograft rejection, the authors discuss the…”
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T Regulatory Cells and Migration by Chen, D., Bromberg, J. S.

“…Migration behavior of regulatory T cells critically influences their suppressive activities in vivo and expression of chemokine receptors, selectins, and…”
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Nine Things You Might Not Say or Hear in Transplantation by Bromberg, J. S., Halloran, P. F.

“…It is time to stir up some debate on areas of organ transplantation that need sharper focus…”
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The Islet Transplant Experiment: Time for a Reassessment by Bromberg, J. S., Kaplan, B., Halloran, P. F., Robertson, R. P.

“…Recent data further defining the long term outcomes and complications associated with islet transplantation require a reassessment of the clinical trials. Also…”
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