Search Results - "Broman, Meaghan M"

Heterogeneity of human prostate carcinoma‐associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment by Vickman, Renee E., Broman, Meaghan M., Lanman, Nadia A., Franco, Omar E., Sudyanti, Putu Ayu G., Ni, Yang, Ji, Yuan, Helfand, Brian T., Petkewicz, Jacqueline, Paterakos, Michael C., Crawford, Susan E., Ratliff, Timothy L., Hayward, Simon W.

“…Background Carcinoma–associated fibroblasts (CAF) are a heterogeneous group of cells within the tumor microenvironment (TME) that can promote tumorigenesis in…”
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Targeting Plk1 to Enhance Efficacy of Olaparib in Castration-Resistant Prostate Cancer by Li, Jie, Wang, Ruixin, Kong, Yifan, Broman, Meaghan M, Carlock, Colin, Chen, Long, Li, Zhiguo, Farah, Elia, Ratliff, Timothy L, Liu, Xiaoqi

“…Olaparib is an FDA-approved PARP inhibitor (PARPi) that has shown promise as a synthetic lethal treatment approach for BRCA-mutant castration-resistant…”
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Inflammation impacts androgen receptor signaling in basal prostate stem cells through interleukin 1 receptor antagonist by Cooper, Paula O., Yang, Jiang, Wang, Hsing-Hui, Broman, Meaghan M., Jayasundara, Shyaman Madhawa, Sahoo, Subhransu Sekhar, Yan, Bingyu, Awdalkreem, Gada D., Cresswell, Gregory M., Wang, Liang, Goossens, Emery, Lanman, Nadia A., Doerge, Rebecca W., Zheng, Faye, Cheng, Liang, Alqahtani, Saeed, Crist, Scott A., Braun, Robert E., Kazemian, Majid, Jerde, Travis J., Ratliff, Timothy L.

“…Chronic prostate inflammation in patients with benign prostate hyperplasia (BPH) correlates with the severity of symptoms. How inflammation contributes to…”
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Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs by Cresswell, Gregory M, Wang, Bingbing, Kischuk, Erin M, Broman, Meaghan M, Alfar, Rami A, Vickman, Renee E, Dimitrov, Dimiter S, Kularatne, Sumith A, Sundaram, Chandru P, Singhal, Sunil, Eruslanov, Evgeniy B, Crist, Scott A, Elzey, Bennett D, Ratliff, Timothy L, Low, Philip S

“…Although immunotherapies of tumors have demonstrated promise for altering the progression of malignancies, immunotherapies have been limited by an…”
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TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease by Vickman, Renee E., Aaron-Brooks, LaTayia, Zhang, Renyuan, Lanman, Nadia A., Lapin, Brittany, Gil, Victoria, Greenberg, Max, Sasaki, Takeshi, Cresswell, Gregory M., Broman, Meaghan M., Paez, J. Sebastian, Petkewicz, Jacqueline, Talaty, Pooja, Helfand, Brian T., Glaser, Alexander P., Wang, Chi-Hsiung, Franco, Omar E., Ratliff, Timothy L., Nastiuk, Kent L., Crawford, Susan E., Hayward, Simon W.

“…Autoimmune (AI) diseases can affect many organs; however, the prostate has not been considered to be a primary target of these systemic inflammatory processes…”
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Identification of LIMK2 as a therapeutic target in castration resistant prostate cancer by Nikhil, Kumar, Chang, Lei, Viccaro, Keith, Jacobsen, Max, McGuire, Callista, Satapathy, Shakti R., Tandiary, Michael, Broman, Meaghan M., Cresswell, Gregory, He, Yizhou J., Sandusky, George E., Ratliff, Timothy L., Chowdhury, Dipanjan, Shah, Kavita

“…This study identified LIMK2 kinase as a disease-specific target in castration resistant prostate cancer (CRPC) pathogenesis, which is upregulated in response…”
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Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma by Aayush, Aayush, Darji, Saloni, Dhawan, Deepika, Enstrom, Alexander, Broman, Meaghan M, Idrees, Muhammad T, Kaimakliotis, Hristos, Ratliff, Timothy, Knapp, Deborah, Thompson, David

“…Cystoscopic visualization of bladder cancer is an essential method for initial bladder cancer detection and diagnosis, transurethral resection, and monitoring…”
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Distinct expression patterns of SULT2B1b in human prostate epithelium by Yang, Jiang, Broman, Meaghan M., Cooper, Paula O., Lanman, Nadia A., Strand, Douglas W., Morrissey, Colm, Ratliff, Timothy L.

“…Background SULT2B1b (sulfotransferase family cytosolic 2B member 1b) catalyzes the sulfate conjugation of substrates such as cholesterol and oxysterols. Our…”
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Pathology in Practice by Broman, Meaghan M, Miller, Margaret A

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Prevalence and significance of an ultrasonographic colonic muscularis hyperechoic band paralleling the serosal layer in dogs by Heng, Hock Gan, Lim, Chee Kin, Miller, Margaret A., Broman, Meaghan M.

“…The muscularis layer of the canine colon has been reported to appear homogeneously hypoechoic on ultrasonography. A hyperechoic band in the muscularis layer…”
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Pathology in Practice by Broman, Meaghan M., Miller, Margaret A.

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Abstract 5075: Single-cell RNAseq of human prostate cancer-associated fibroblasts reveals distinct subpopulations that may promote inflammatory cell recruitment to the tumor microenvironment by Vickman, Renee E., Broman, Meaghan M., Atallah, Nadia M., Sudyanti, Ayu, Franco, Omar E., Ratliff, Timothy L., Hayward, Simon W.

“…Abstract Introduction: Carcinoma-associated fibroblasts (CAF) are a heterogeneous group of cells within the tumor microenvironment that can promote…”
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Inflammation and Benign Prostatic Hyperplasia: Role of Immune Cells and their Interactions in Chronic Inflammation and Cellular Hyperplasia by Broman, Meaghan M

“…Benign prostatic hyperplasia (BPH) is a common urologic condition among older men, affecting approximately half of men by age 50 and nearly 80% by age 80…”
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Pathology in Practice: mediastinal lymphoma with hemorrhagic pleural effusion and pulmonary atelectasis in a cat by Broman, Meaghan M, Miller, Margaret A

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