Search Results - "Brokstad, Karl"

Not just antibodies: B cells and T cells mediate immunity to COVID-19 by Cox, Rebecca J., Brokstad, Karl A.

“…Recent reports that antibodies to SARS-CoV-2 are not maintained in the serum following recovery from the virus have caused alarm. However, the absence of…”
Get full text

Long COVID in a prospective cohort of home-isolated patients by Blomberg, Bjørn, Mohn, Kristin Greve-Isdahl, Brokstad, Karl Albert, Zhou, Fan, Linchausen, Dagrun Waag, Hansen, Bent-Are, Lartey, Sarah, Onyango, Therese Bredholt, Kuwelker, Kanika, Sævik, Marianne, Bartsch, Hauke, Tøndel, Camilla, Kittang, Bård Reiakvam, Cox, Rebecca Jane, Langeland, Nina

“…Long-term complications after coronavirus disease 2019 (COVID-19) are common in hospitalized patients, but the spectrum of symptoms in milder cases needs…”
Get full text

Influenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines by Sridhar, Saranya, Brokstad, Karl A, Cox, Rebecca J

“…Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics. Influenza vaccination is the major method of prophylaxis…”
Get full text

Current concepts on Sjögren's syndrome – classification criteria and biomarkers by Jonsson, Roland, Brokstad, Karl A., Jonsson, Malin V., Delaleu, Nicolas, Skarstein, Kathrine

“…Sjögren's syndrome is a lymphoproliferative disease with autoimmune features characterized by mononuclear cell infiltration of exocrine glands, notably the…”
Get full text

Implication of Epstein‐Barr Virus Infection in Disease‐Specific Autoreactive B Cell Activation in Ectopic Lymphoid Structures of Sjögren's Syndrome by Croia, Cristina, Astorri, Elisa, Murray‐Brown, William, Willis, Amanda, Brokstad, Karl A., Sutcliffe, Nurhan, Piper, Kim, Jonsson, Roland, Tappuni, Anwar R., Pitzalis, Costantino, Bombardieri, Michele

“…Objective To examine whether the B cell tropic γ‐herpesvirus Epstein‐Barr virus (EBV) is aberrantly expressed in its latent and lytic forms within ectopic…”
Get full text

Vaccination with adjuvanted recombinant neuraminidase induces broad heterologous, but not heterosubtypic, cross-protection against influenza virus infection in mice by Wohlbold, Teddy John, Nachbagauer, Raffael, Xu, Haoming, Tan, Gene S, Hirsh, Ariana, Brokstad, Karl A, Cox, Rebecca J, Palese, Peter, Krammer, Florian

“…In an attempt to assess the cross-protective potential of the influenza virus neuraminidase (NA) as a vaccine antigen, different subtypes of recombinant NA…”
Get full text

Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer by Qu, Yi, Olsen, Jan Roger, Yuan, Xing, Cheng, Phil F, Levesque, Mitchell P, Brokstad, Karl A, Hoffman, Paul S, Oyan, Anne Margrete, Zhang, Weidong, Kalland, Karl-Henning, Ke, Xisong

“…The small molecule nitazoxanide (NTZ) was identified as a Wnt inhibitor by promoting protein citrullination of β-catenin through increased cytosolic calcium…”
Get full text

Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients by Mohn, Kristin G-I, Bredholt, Geir, Zhou, Fan, Madsen, Anders, Onyango, Therese B, Fjelltveit, Elisabeth B, Jalloh, Sarah L, Brokstad, Karl A, Cantoni, Diego, Mayora-Neto, Martin, Temperton, Nigel, Langeland, Nina, Cox, Rebecca J

“…Neutralizing antibodies are important for protection against the pandemic SARS-CoV-2 virus, and long-term memory responses determine the risk of re-infection…”
Get full text

Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer by Qu, Yi, Gharbi, Naouel, Yuan, Xing, Olsen, Jan Roger, Blicher, Pernille, Dalhus, Bjørn, Brokstad, Karl A., Lin, Biaoyang, Øyan, Anne Margrete, Zhang, Weidong, Kalland, Karl-Henning, Ke, Xisong

“…Oncogenic mutations of the Wnt (wingless)/β-catenin pathway are frequently observed in major cancer types. Thus far, however, no therapeutic agent targeting…”
Get full text

Cytokine Concentrations in Plasma from Children with Severe and Non-Severe Community Acquired Pneumonia by Haugen, Johanne, Chandyo, Ram K, Brokstad, Karl A, Mathisen, Maria, Ulak, Manjeswori, Basnet, Sudha, Valentiner-Branth, Palle, Strand, Tor A

“…Children in low and middle-income countries have a high burden of pneumonia. Measuring the cytokine responses may be useful to identify novel markers for…”
Get full text

Boosting of Cross-Reactive and Protection-Associated T Cells in Children After Live Attenuated Influenza Vaccination by Mohn, Kristin G. I., Zhou, Fan, Brokstad, Karl A., Sridhar, Saranya, Cox, Rebecca J.

“…Background. Live attenuated influenza vaccines (LAIVs) stimulate a multifaceted immune response including cellular immunity, which may provide protection…”
Get full text

Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for In Vivo Protection in a Serum Transfer Mouse Challenge Model by Jacobsen, Henning, Rajendran, Madhusudan, Choi, Angela, Sjursen, Haakon, Brokstad, Karl A, Cox, Rebecca J, Palese, Peter, Krammer, Florian, Nachbagauer, Raffael

“…The immunogenicity of current influenza virus vaccines is assessed by measuring an increase of influenza virus-specific antibodies in a hemagglutination…”
Get full text

Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival by Szyszko, Ewa A, Brokstad, Karl A, Oijordsbakken, Gunnvor, Jonsson, Malin V, Jonsson, Roland, Skarstein, Kathrine

“…The presence of circulating Ro/SSA and La/SSB autoantibodies has become an important marker in the classification criteria for primary Sjögren's syndrome…”
Get full text

Live-Attenuated Influenza Vaccine Induces Tonsillar Follicular T Helper Cell Responses That Correlate With Antibody Induction by Lartey, Sarah, Zhou, Fan, Brokstad, Karl A, Mohn, Kristin G-I, Slettevoll, Steffen A, Pathirana, Rishi D, Cox, Rebecca J

“…Abstract Background Influenza remains a major threat to public health. Live-attenuated influenza vaccines (LAIV) have been shown to be effective, particularly…”
Get full text

High intake of fatty fish, but not of lean fish, affects serum concentrations of TAG and HDL-cholesterol in healthy, normal-weight adults: a randomised trial by Hagen, Ingrid V., Helland, Anita, Bratlie, Marianne, Brokstad, Karl A., Rosenlund, Grethe, Sveier, Harald, Mellgren, Gunnar, Gudbrandsen, Oddrun A.

“…The aim of the present study was to examine whether high intake of lean or fatty fish (cod and farmed salmon, respectively) by healthy, normal-weight adults…”
Get full text

Symptom Burden and Immune Dynamics 6 to 18 Months Following Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infection (SARS-CoV-2): A Case-control Study by Fjelltveit, Elisabeth B, Blomberg, Bjørn, Kuwelker, Kanika, Zhou, Fan, Onyango, Therese B, Brokstad, Karl A, Elyanow, Rebecca, Kaplan, Ian M, Tøndel, Camilla, Mohn, Kristin G I, Özgümüş, Türküler, Cox, Rebecca J, Langeland, Nina

“…Abstract Background The burden and duration of persistent symptoms after nonsevere coronavirus disease 2019 (COVID-19) remains uncertain. This study aimed to…”
Get full text

SARS-CoV-2 infection induces long-lived B and T-cell responses up to 15 months post-infection, irrespective of disease severity by Mohn, Kristin G.-I., Bredholt, Geir, Onyango, Therese Bredholt, Brokstad, Karl A., Zhou, Fan, Holter, Jan Cato, Tonby, Kristian, Dyrhol-Riise, Anne Ma, Cox, Rebecca Jane

“…[Display omitted]…”
Get full text

H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production by Brauner, Susanna, Folkersen, Lasse, Kvarnström, Marika, Meisgen, Sabrina, Petersen, Sven, Franzén-Malmros, Michaela, Mofors, Johannes, Brokstad, Karl A, Klareskog, Lars, Jonsson, Roland, Westerberg, Lisa S, Trollmo, Christina, Malmström, Vivianne, Ambrosi, Aurelie, Kuchroo, Vijay K, Nordmark, Gunnel, Wahren-Herlenius, Marie

“…Vaccination of patients with rheumatic disease has been reported to result in lower antibody titres than in healthy individuals. However, studies primarily…”
Get more information

Longevity of B-Cell and T-Cell Responses After Live Attenuated Influenza Vaccination in Children by Mohn, Kristin G.-I., Bredholt, Geir, Brokstad, Karl A., Pathirana, Rishi D., Aarstad, Hans J., Tøndel, Camilla, Cox, Rebecca J.

“…Background. The live attenuated influenza vaccine (LAIV) is the preferred vaccine for children, but the mechanisms behind protective immune responses are…”
Get full text

Seroconversion in household members of COVID-19 outpatients by Cox, Rebecca J, Brokstad, Karl A, Krammer, Florian, Langeland, Nina, Blomberg, Bjørn, Kuwelker, Kanika, Lartey, Sarah, Linchausen, Dagrun Waag, Mohn, Kristin GI, Real, Francisco Gomez, Bansal, Amit, Bredholt, Geir, Madsen, Anders, Onanygo, Therese Bredholt, Trieu, Mai Chi, Vahokoski, Juha, Zhou, Fan

Get full text