Search Results - "Brokos, Barbara"
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RAGE-TLR Crosstalk Sustains Chronic Inflammation in Neurodegeneration
Published in Molecular neurobiology (01-02-2018)“…Chronic inflammatory reactions are consistenly present in neurodegeneration of Alzheimer type and are considered important factors that accelerate progression…”
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Insulin Resistance in Alzheimer Disease: p53 and MicroRNAs as Important Players
Published in Current topics in medicinal chemistry (01-01-2017)“…Glucose homeostasis is crucial for neuronal survival, synaptic plasticity, and is indispensable for learning and memory. Reduced sensitivity of cells to…”
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Antimutagenic activity of anthocyanins isolated from Aronia melanocarpa fruits
Published in Cancer letters (28-10-1997)“…Anthocyanins belong to the flavonoid family and are ubiquitous in plants, especially in flower petals and fruit peels. We established that anthocyanins…”
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4
Current and Near-Future Treatment of Alzheimer's Disease
Published in Current neuropharmacology (01-01-2022)“…Recent findings have improved our understanding of the multifactorial nature of AD. While in early asymptomatic stages of AD, increased amyloid-β synthesis and…”
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Antimutagenic activity of alkylresorcinols from cereal grains
Published in Cancer letters (23-08-1996)“…Alkylresorcinols, natural amphiphilic compounds commonly found in cereal grains, markedly decreased mutagenic activity of four standard mutagens examined in…”
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Immunomodulating Polysaccharide Fractions of Menyanthes trifoliata L
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01-07-2004)“…Looking for new plant sources of immunomodulating agents polysaccharide-rich fractions (PS) from Menyanthes trifoliata L. (Menyanthaceae) have been isolated…”
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DNA repair of hydrogen peroxide-induced damage in human lymphocytes in the presence of four antimutagens. A study with alkaline single cell gel electrophoresis (comet assay)
Published in Cellular & molecular biology letters (2001)“…We assessed four antimutagenic compounds' influences on DNA repair in human lymphocytes exposed in vitro to hydrogen peroxide (20 microM, 5 min, at 4 degrees…”
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A comparison of the methods applied to detect apoptosis in genotoxically-damaged lymphocytes cultured in the presence of four antimutagens
Published in Cellular & molecular biology letters (2001)“…The sensitivity of the available methods of apoptosis detection in lymphocyte cultures was tested. Cells were preincubated with genotoxic agents: hydrogen…”
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A high frequency of apoptosis was found in cultures of lymphocytes isolated from the venous blood of children born with a low birth weight
Published in Cellular & molecular biology letters (2004)“…Children born with a low birth weight (below 2500 g) exhibit a slower rate of development, and a greater tendency towards morbidity and mortality, together…”
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Impact of four antimutagens on apoptosis in genotoxically damaged lymphocytes in vitro
Published in Cellular & molecular biology letters (2001)“…An antimutagenic activity of fluphenazine, todralazine, anthocyanins and alkylresorcinols was established in a battery of short-term cytogenetic tests. One of…”
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Evaluation of antimutagenic effect of todralazine in cultured lymphocytes
Published in Mutagenesis (01-03-2000)“…Todralazine, an antihypertensive drug from the hydrazinophthalazine group, significantly decreased the activities of benzo[a]pyrene and mitomycin C in three…”
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Antimutagenic activity of fluphenazine in short-term tests
Published in Mutagenesis (01-01-2001)“…Fluphenazine, an antipsychotic drug that belongs to the phenothiazine family, reduced the genotoxicity of standard direct- and indirect-acting mutagens in the…”
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