Search Results - "Broekman, L."

Advances in local therapy for glioblastoma — taking the fight to the tumour by van Solinge, Thomas S., Nieland, Lisa, Chiocca, E. Antonio, Broekman, Marike L. D.

“…Despite advances in neurosurgery, chemotherapy and radiotherapy, glioblastoma remains one of the most treatment-resistant CNS malignancies, and the tumour…”
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Potential impact of invasive surgical procedures on primary tumor growth and metastasis by Alieva, Maria, van Rheenen, Jacco, Broekman, Marike L. D.

“…Surgical procedures such as tumor resection and biopsy are still the gold standard for diagnosis and (determination of) treatment of solid tumors, and are…”
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Natural and Artificial Intelligence in Neurosurgery: A Systematic Review by Senders, Joeky T, Arnaout, Omar, Karhade, Aditya V, Dasenbrock, Hormuzdiyar H, Gormley, William B, Broekman, Marike L, Smith, Timothy R

“…Abstract BACKGROUND Machine learning (ML) is a domain of artificial intelligence that allows computer algorithms to learn from experience without being…”
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Agents for fluorescence-guided glioma surgery: a systematic review of preclinical and clinical results by Senders, Joeky T., Muskens, Ivo S., Schnoor, Rosalie, Karhade, Aditya V., Cote, David J., Smith, Timothy R., Broekman, Marike L. D.

“…Background Fluorescence-guided surgery (FGS) is a technique used to enhance visualization of tumor margins in order to increase the extent of tumor resection…”
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Glioblastoma hijacks microglial gene expression to support tumor growth by Maas, Sybren L N, Abels, Erik R, Van De Haar, Lieke L, Zhang, Xuan, Morsett, Liza, Sil, Srinjoy, Guedes, Joana, Sen, Pritha, Prabhakar, Shilpa, Hickman, Suzanne E, Lai, Charles P, Ting, David T, Breakefield, Xandra O, Broekman, Marike L D, El Khoury, Joseph

“…Glioblastomas are the most common and lethal primary brain tumors. Microglia, the resident immune cells of the brain, survey their environment and respond to…”
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Developer perspectives on the ethics of AI-driven neural implants: a qualitative study by van Stuijvenberg, Odile C., Broekman, Marike L. D., Wolff, Samantha E. C., Bredenoord, Annelien L., Jongsma, Karin R.

“…Convergence of neural implants with artificial intelligence (AI) presents opportunities for the development of novel neural implants and improvement of…”
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Prognostic relevance of epilepsy at presentation in glioblastoma patients by Berendsen, Sharon, Varkila, Meri, Kroonen, Jérôme, Seute, Tatjana, Snijders, Tom J, Kauw, Frans, Spliet, Wim G M, Willems, Marie, Poulet, Christophe, Broekman, Marike L, Bours, Vincent, Robe, Pierre A

“…Epileptogenic glioblastomas are thought to convey a favorable prognosis, either due to early diagnosis or potential antitumor effects of antiepileptic drugs…”
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True shared decision-making in neurosurgical oncology: does it really exist? by Jessurun, Charissa A. C., Broekman, Marike L. D.

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Trends in cerebrospinal fluid leak rates following the extended endoscopic endonasal approach for anterior skull base meningioma: a meta-analysis over the last 20 years by Zamanipoor Najafabadi, Amir H., Khan, Danyal Z., Muskens, Ivo S, Broekman, Marike L. D., Dorward, Neil L., van Furth, Wouter R., Marcus, Hani J.

“…Objective The extended endoscopic approach provides unimpaired visualization and direct access to ventral skull base pathology, but is associated with…”
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Neurocognitive changes after awake surgery in glioma patients: a retrospective cohort study by van Kessel, Emma, Snijders, Tom J., Baumfalk, Anniek E., Ruis, Carla, van Baarsen, Kirsten M., Broekman, Marike L., van Zandvoort, Martine J. E., Robe, Pierre A.

“…Purpose Deficits in neurocognitive functioning (NCF) frequently occur in glioma patients. Both treatment and the tumor itself contribute to these deficits. In…”
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The endoscope-assisted supraorbital “keyhole” approach for anterior skull base meningiomas: an updated meta-analysis by Khan, Danyal Z., Muskens, Ivo S., Mekary, Rania A., Zamanipoor Najafabadi, Amir H., Helmy, Adel E., Reisch, Robert, Broekman, Marike L. D., Marcus, Hani J.

“…Introduction The gold-standard treatment for symptomatic anterior skull base meningiomas is surgical resection. The endoscope-assisted supraorbital “keyhole”…”
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Preventing inflammation inhibits biopsy-mediated changes in tumor cell behavior by Alieva, Maria, Margarido, Andreia S., Wieles, Tamara, Abels, Erik R., Colak, Burcin, Boquetale, Carla, Jan Noordmans, Herke, Snijders, Tom J., Broekman, Marike L., van Rheenen, Jacco

“…Although biopsies and tumor resection are prognostically beneficial for glioblastomas (GBM), potential negative effects have also been suggested. Here, using…”
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Palliative Care in Severe Neurotrauma Patients in the Intensive Care Unit by Dolmans, Rianne G. F., Robertson, Faith C., Eijkholt, Marleen, van Vliet, Peter, Broekman, Marike L. D.

“…Traumatic brain injury (TBI) is a significant cause of mortality and morbidity worldwide and many patients with TBI require intensive care unit (ICU)…”
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Comparative Analysis Identifies Similarities between the Human and Murine Microglial Sensomes by Abels, Erik R, Nieland, Lisa, Hickman, Suzanne, Broekman, Marike L D, El Khoury, Joseph, Maas, Sybren L N

“…One of the essential functions of microglia is to continuously sense changes in their environment and adapt to those changes. For this purpose, they use a set…”
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A snapshot of European neurosurgery December 2019 vs. March 2020: just before and during the Covid-19 pandemic by Mathiesen, T., Arraez, M., Asser, T., Balak, N., Barazi, S., Bernucci, C., Bolger, C., Broekman, M. L. D., Demetriades, A. K., Feldman, Z., Fontanella, M. M., Foroglou, N., Lafuente, J., Maier, A. D., Meyer, B., Niemelä, M., Roche, P. H., Sala, F., Samprón, N., Sandvik, U., Schaller, K., Thome, C., Thys, M., Tisell, M., Vajkoczy, P., Visocchi, M.

“…Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or Covid-19), which began as an epidemic in China and spread globally as a pandemic, has…”
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AAV-mediated gene delivery in adult GM1-gangliosidosis mice corrects lysosomal storage in CNS and improves survival by Baek, Rena C, Broekman, Marike L D, Leroy, Stanley G, Tierney, Laryssa A, Sandberg, Michael A, d'Azzo, Alessandra, Seyfried, Thomas N, Sena-Esteves, Miguel

“…GM1-gangliosidosis is a glycosphingolipid (GSL) lysosomal storage disease caused by a genetic deficiency of acid β-galactosidase (βgal), which results in the…”
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Whole genome sequencing in (recurrent) glioblastoma: challenges related to informed consent procedures and data sharing by Hasner, Mira C., van Opijnen, Mark P., de Vos, Filip Y. F., Cuppen, Edwin, Broekman, Marike L. D.

“…Increased use of whole genome sequencing (WGS) in neuro-oncology for diagnostics and research purposes necessitates a renewed conversation about informed…”
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Quantification and size-profiling of extracellular vesicles using tunable resistive pulse sensing by Maas, Sybren L N, De Vrij, Jeroen, Broekman, Marike L D

“…Extracellular vesicles (EVs), including 'microvesicles' and 'exosomes', are highly abundant in bodily fluids. Recent years have witnessed a tremendous increase…”
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Systemic therapy following craniotomy in patients with a solitary breast cancer brain metastasis by Hulsbergen, Alexander F. C., Cho, Logan D., Mammi, Marco, Lamba, Nayan, Smith, Timothy R., Brastianos, Priscilla K., Broekman, Marike L. D., Lin, Nancy U.

“…Purpose To describe practice patterns and patient outcomes with respect to the use of postoperative systemic therapy (ST) after resection of a solitary breast…”
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Clinical challenges of glioma and pregnancy: a systematic review by van Westrhenen, A., Senders, J. T., Martin, E., DiRisio, A. C., Broekman, M. L. D.

“…Introduction This review aims to summarize challenges in clinical management of concomitant gliomas and pregnancy and provides suggestions for this management…”
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