Search Results - "Brodzka, Anna"

Simultaneous Enantiodivergent Synthesis of Diverse Lactones and Lactams via Sequential One-Pot Enzymatic Kinetic Resolution-Ring-Closing Metathesis Reactions by Brodzka, Anna, Koszelewski, Dominik, Ostaszewski, Ryszard

“…One of the goals of diversity-oriented synthesis is to achieve the structural diversity of obtained compounds. As most biologically active compounds are…”
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Dual Activity of Grubbs-Type Catalyst in the Transvinylation of Carboxylic Acids and Ring-Closing Metathesis Reactions by Brodzka, Anna, Koszelewski, Dominik, Ostaszewski, Ryszard

“…The development of a multifunctional catalyst, which mimics the promiscuity of enzymes, that would catalyze more than one chemical transformation in a single…”
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Multicomponent Reactions Accelerated by Aqueous Micelles by Paprocki, Daniel, Madej, Arleta, Koszelewski, Dominik, Brodzka, Anna, Ostaszewski, Ryszard

“…Multicomponent reactions are powerful synthetic tools for the efficient creation of complex organic molecules in an one-pot one-step fashion. Moreover, the…”
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Selective Esterification of Phosphonic Acids by Trzepizur, Damian, Brodzka, Anna, Koszelewski, Dominik, Ostaszewski, Ryszard

“…Here, we report straightforward and selective synthetic procedures for mono- and diesterification of phosphonic acids. A series of alkoxy group donors were…”
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Synthesis of Enantiomerically Pure 5,6‐Dihydropyran‐2‐ones via Chemoenzymatic Sequential DKR‐RCM Reaction by Koszelewski, Dominik, Borys, Filip, Brodzka, Anna, Ostaszewski, Ryszard

“…The enantiomerically pure 5,6‐dihydropyran‐2‐ones play a crucial role as the building blocks in the synthesis of various bioactive compounds. A new…”
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Evaluation of Antibacterial Activity against Nosocomial Pathogens of an Enzymatically Derived α-Aminophosphonates Possessing Coumarin Scaffold by Kowalczyk, Paweł, Koszelewski, Dominik, Brodzka, Anna, Kramkowski, Karol, Ostaszewski, Ryszard

“…The purpose of the present study was to evaluate the synergistic effect of two important pharmacophores, coumarin and α-amino dimethyl phosphonate moieties, on…”
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The Influence of Ligands on the Pd-Catalyzed Diarylation of Vinyl Esters by Brodzka, Anna, Koszelewski, Dominik, Trzeciak, Anna, Ruzik, Lena, Grela, Malgorzata, Ostaszewski, Ryszard

“…The impact of ligands on the palladium-catalyzed 1,2-diarylation reaction course is presented. The application of Pd-dmpzc as a catalyst provides an efficient,…”
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Enzymatic Synthesis of a Novel Coumarin Aminophosphonates: Antibacterial Effects and Oxidative Stress Modulation on Selected E. coli Strains by Koszelewski, Dominik, Kowalczyk, Paweł, Brodzka, Anna, Hrunyk, Anastasiia, Kramkowski, Karol, Ostaszewski, Ryszard

“…The objective of the present study was to evaluate the synergistic effect of two important pharmacophores, coumarin and α-amino dimethyl phosphonate moieties,…”
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The amine as carbonyl precursor in the chemoenzymatic synthesis of Passerini adducts in aqueous medium by Madej, Arleta, Koszelewski, Dominik, Paprocki, Daniel, Brodzka, Anna, Ostaszewski, Ryszard

“…A new simple environmentally friendly protocol based on sequential chemoenzymatic synthesis of α-acyloxy carboxyamides from amines as a carbonyl precursor is…”
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Mystery of the Passerini Reaction for the Synthesis of the Antimicrobial Peptidomimetics against Nosocomial Pathogenic Bacteria by Wavhal, Deepak S, Koszelewski, Dominik, Gulko, Cezary, Kowalczyk, Paweł, Brodzka, Anna, Kramkowski, Karol, Ostaszewski, Ryszard

“…The first example of applying salicylaldehyde derivatives, as well as coumarin with the formyl group at the C8 position in its structure, as carbonyl partners…”
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Intensification of Double Kinetic Resolution of Chiral Amines and Alcohols via Chemoselective Formation of a Carbonate-Enzyme Intermediate by Samsonowicz-Górski, Jan, Brodzka, Anna, Ostaszewski, Ryszard, Koszelewski, Dominik

“…Chiral amines and alcohols are synthons of numerous pharmaceutically-relevant compounds. The previously developed enzymatic kinetic resolution approaches…”
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The Synthesis and Evaluation of Diethyl Benzylphosphonates as Potential Antimicrobial Agents by Brodzka, Anna, Kowalczyk, Paweł, Trzepizur, Damian, Koszelewski, Dominik, Kramkowski, Karol, Szymczak, Mateusz, Wypych, Aleksandra, Lizut, Rafał, Ostaszewski, Ryszard

“…The impact of substituent at phenyl ring of diethyl benzylphosphonate derivatives on cytotoxic activity was studied. The organophosphonates were obtained based…”
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Synthesis and Antimicrobial Activity of the Pathogenic E. coli Strains of p -Quinols: Additive Effects of Copper-Catalyzed Addition of Aryl Boronic Acid to Benzoquinones by Koszelewski, Dominik, Kowalczyk, Paweł, Samsonowicz-Górski, Jan, Hrunyk, Anastasiia, Brodzka, Anna, Łęcka, Justyna, Kramkowski, Karol, Ostaszewski, Ryszard

“…A mild and efficient protocol for the synthesis of -quinols under aqueous conditions was developed. The pivotal role of additives in the copper-catalyzed…”
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The Synthesis and Evaluation of Amidoximes as Cytotoxic Agents on Model Bacterial E. coli Strains by Samsonowicz-Górski, Jan, Kowalczyk, Paweł, Koszelewski, Dominik, Brodzka, Anna, Szymczak, Mateusz, Kramkowski, Karol, Ostaszewski, Ryszard

“…The biological research on newly synthesized amidoximes, Boc-protected amidoximes and Boc-derived amidines, obtained by a reduction of the parent amidoximes is…”
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The sustainable synthesis of peptidomimetics via chemoenzymatic tandem oxidation-Ugi reaction by Madej, Arleta, Koszelewski, Dominik, Paprocki, Daniel, Brodzka, Anna, Ostaszewski, Ryszard

“…A simply and green synthetic protocol based on the selective laccase-oxidation of alcohol to a corresponding aldehyde and a following Ugi reaction in a…”
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The Evaluation of DHPMs as Biotoxic Agents on Pathogen Bacterial Membranes by Gawdzik, Barbara, Kowalczyk, Paweł, Koszelewski, Dominik, Brodzka, Anna, Masternak, Joanna, Kramkowski, Karol, Wypych, Aleksandra, Ostaszewski, Ryszard

“…Herein, we present biological studies on 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) obtained via Biginelli reaction catalyzed by NH4Cl under solvent-free…”
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Wheat germ lipase: isolation, purification and applications by Kublicki, Marcin, Koszelewski, Dominik, Brodzka, Anna, Ostaszewski, Ryszard

“…In recent years, wheat germ lipase (WGL) is attracting considerable interest. To date, several WGL applications have already been described: (i) fats and oils…”
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Selective Palladium‐Catalyzed α,β‐Homodiarylation of Vinyl Esters in Aqueous Medium by Trzepizur, Damian, Brodzka, Anna, Koszelewski, Dominik, Wilk, Monika, Ostaszewski, Ryszard

“…A palladium‐catalyzed 1,2‐diarylation of vinyl esters with arylboronic acids in water has been developed. This newly elaborated protocol features a good…”
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Evaluation of gem-Diacetates as Alternative Reagents for Enzymatic Regio- and Stereoselective Acylation of Alcohols by Koszelewski, Dominik, Brodzka, Anna, Madej, Arleta, Trzepizur, Damian, Ostaszewski, Ryszard

“…Geminal diacetates have been used as sustainable acyl donors for enzymatic acylation of chiral and nonchiral alcohols. Especially, it was revealed that geminal…”
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Studies on the Synthesis of Endocyclic Enol Lactones via a RCM of Selected Vinyl Esters by Brodzka, Anna, Borys, Filip, Koszelewski, Dominik, Ostaszewski, Ryszard

“…The novel and efficient approach toward the synthesis of endocyclic enol lactones was devised based on ring-closing metathesis of unsaturated carboxylic acids…”
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