Search Results - "Brodt, M. D."

The Effect of Gap Formation at the Repair Site on the Strength and Excursion of Intrasynovial Flexor Tendons. AN EXPERIMENTAL STUDY ON THE EARLY STAGES OF TENDON-HEALING IN DOGS by GELBERMAN, RICHARD H, BOYER, MARTIN I, BRODT, MICHAEL D, WINTERS, STEVEN C, SILVA, MATTHEW J

“…BackgroundElongation (gap formation) at the repair site has been associated with the formation of adhesions and a poor functional outcome after repair of…”
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Early biocompatibility of crosslinked and non-crosslinked biologic meshes in a porcine model of ventral hernia repair by Melman, L., Jenkins, E. D., Hamilton, N. A., Bender, L. C., Brodt, M. D., Deeken, C. R., Greco, S. C., Frisella, M. M., Matthews, B. D.

“…Purpose Biologic meshes have unique physical properties as a result of manufacturing techniques such as decellularization, crosslinking, and sterilization. The…”
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Accuracy of peripheral quantitative computed tomography (pQCT) for assessing area and density of mouse cortical bone by Brodt, M D, Pelz, G B, Taniguchi, J, Silva, M J

“…Peripheral quantitative computed tomography (pQCT) is increasingly used for measurement of cortical bone geometry and density in mice. We evaluated the…”
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Effects of increased in vivo excursion on digital range of motion and tendon strength following flexor tendon repair by Silva, M J, Brodt, M D, Boyer, M I, Morris, T S, Dinopoulos, H, Amiel, D, Gelberman, R H

“…Postoperative rehabilitation is an important factor in determining functional outcome following intrasynovial flexor tendon repair. We hypothesized that a…”
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Histologic and biomechanical evaluation of a novel macroporous polytetrafluoroethylene knit mesh compared to lightweight and heavyweight polypropylene mesh in a porcine model of ventral incisional hernia repair by Melman, L., Jenkins, E. D., Hamilton, N. A., Bender, L. C., Brodt, M. D., Deeken, C. R., Greco, S. C., Frisella, M. M., Matthews, B. D.

“…Purpose To evaluate the biocompatibility of heavyweight polypropylene (HWPP), lightweight polypropylene (LWPP), and monofilament knit polytetrafluoroethylene…”
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Flexor digitorum profundus tendon-to-bone repair: an ex vivo biomechanical analysis of 3 pullout suture techniques by Silva, M J, Hollstien, S B, Brodt, M D, Boyer, M I, Tetro, A M, Gelberman, R H

“…Avulsions or distal transsections of the flexor digitorum profundus tendon are typically repaired by direct suture of tendon to the distal phalanx. The tensile…”
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Mechanical behavior of human morselized cancellous bone in triaxial compression testing by Brodt, M D, Swan, C C, Brown, T D

“…Despite its widespread use as graft material in orthopaedic surgical procedures, morselized cancellous bone has not yet been well characterized from the…”
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Growing C57B1/6 mice increase whole bone mechanical properties by increasing geometric and material properties by BRODT, M. D, ELLIS, C. B, SILVA, M. J

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Aged mice have enhanced endocortical response and normal periosteal response compared with young‐adult mice following 1 week of axial tibial compression by Brodt, Michael D, Silva, Matthew J

“…With aging, the skeleton may lose its ability to respond to positive mechanical stimuli. We hypothesized that aged mice are less responsive to loading than…”
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Attenuated Response to In Vivo Mechanical Loading in Mice With Conditional Osteoblast Ablation of the Connexin43 Gene (Gja1) by Grimston, Susan K, Brodt, Michael D, Silva, Matthew J, Civitelli, Roberto

“…Introduction: In vitro data suggest that gap junctional intercellular communication mediated by connexin43 (Cx43) plays an important role in bone cell response…”
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Type 1 Diabetes in Young Rats Leads to Progressive Trabecular Bone Loss, Cessation of Cortical Bone Growth, and Diminished Whole Bone Strength and Fatigue Life by Silva, Matthew J, Brodt, Michael D, Lynch, Michelle A, McKenzie, Jennifer A, Tanouye, Kristi M, Nyman, Jeffry S, Wang, Xiaodu

“…People with diabetes have increased risk of fracture disproportionate to BMD, suggesting reduced material strength (quality). We quantified the skeletal…”
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Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis by Grimston, Susan K, Goldberg, Daniel B, Watkins, Marcus, Brodt, Michael D, Silva, Matthew J, Civitelli, Roberto

“…We have shown previously that the effect of mechanical loading on bone depends in part on connexin43 (Cx43). To determine whether Cx43 is also involved in the…”
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SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts by Ross, F. Patrick, Takeshita, Sunao, Namba, Noriyuki, Zhao, Jenny J, Jiang, Yebin, Genant, Harry K, Silva, Matthew J, Brodt, Michael D, Helgason, Cheryl D, Kalesnikoff, Janet, Rauh, Michael J, Humphries, R. Keith, Krystal, Gerald, Teitelbaum, Steven L

“…The hematopoietic-restricted protein Src homology 2-containing inositol-5-phosphatase (SHIP) blunts phosphatidylinositol-3-kinase-initiated signaling by…”
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Decreased Collagen Organization and Content Are Associated With Reduced Strength of Demineralized and Intact Bone in the SAMP6 Mouse by Silva, Matthew J, Brodt, Michael D, Wopenka, Brigitte, Thomopoulos, Stavros, Williams, Derek, Wassen, Maurice HM, Ko, Mike, Kusano, Nozomu, Bank, Ruud A

“…To examine the link between bone material properties and skeletal fragility, we analyzed the mechanical, histological, biochemical, and spectroscopic…”
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Nanoindentation and whole-bone bending estimates of material properties in bones from the senescence accelerated mouse SAMP6 by Silva, Matthew J., Brodt, Michael D., Fan, Zaifeng, Rho, Jae-Young

“…The senescence accelerated mouse, strain P6 (SAMP6) has been described as a model of senile osteoporosis. Recent results from whole-bone bending tests indicate…”
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The Effects of Screw Length on Stability of Simulated Osteoporotic Distal Radius Fractures Fixed With Volar Locking Plates by Wall, Lindley B., MD, Brodt, Michael D., MS, Silva, Matthew J., PhD, Boyer, Martin I., MD, Calfee, Ryan P., MD

“…Purpose Volar plating for distal radius fractures has caused extensor tendon ruptures resulting from dorsal screw prominence. This study was designed to…”
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Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care by Wolf, Timo, MD, Kann, Gerrit, Becker, Stephan, Prof, Stephan, Christoph, MD, Brodt, Hans-Reinhardt, MD, de Leuw, Philipp, MD, Grünewald, Thomas, MD, Vogl, Thomas, MD, Kempf, Volkhard A J, Prof, Keppler, Oliver T, Prof, Zacharowski, Kai, Prof

“…Summary Background In the current epidemic of Ebola virus disease in western Africa, many aid workers have become infected. Some of these aid workers have been…”
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Patient Obesity Influences Pelvic Lift During Cup Insertion in Total Hip Arthroplasty Through a Lateral Transgluteal Approach in Supine Position by Brodt, Steffen, MD, Nowack, Dimitri, MD, Jacob, Benjamin, MD, Krakow, Linda, MD, Windisch, Christoph, MD, Matziolis, Georg, MD

“…Abstract Background Movement of the pelvis during implantation of total hip arthroplasty (THA) has a major influence on the positioning of the acetabular cup…”
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Impaired Marrow Osteogenesis Is Associated With Reduced Endocortical Bone Formation but Does Not Impair Periosteal Bone Formation in Long Bones of SAMP6 Mice by Silva, Matthew J, Brodt, Michael D, Ko, Mike, Abu‐Amer, Yousef

“…We used the SAMP6 osteoporotic mouse to examine the link between marrow osteogenic potential and in vivo cortical bone formation. SAMP6 marrow supported less…”
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Morphological and mechanical properties of caudal vertebrae in the SAMP6 mouse model of senile osteoporosis by Silva, Matthew J, Brodt, Michael D, Uthgenannt, Brian A

“…The senescence-accelerated mouse, strain P6 (SAMP6), is a model of senile osteoporosis with relatively low bone mineral density (BMD), low rates of bone…”
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