Search Results - "Brodsky, Andres"

Genetic Variants in C5 and Poor Response to Eculizumab by Nishimura, Jun-ichi, Yamamoto, Masaki, Hayashi, Shin, Ohyashiki, Kazuma, Ando, Kiyoshi, Brodsky, Andres L, Noji, Hideyoshi, Kitamura, Kunio, Eto, Tetsuya, Takahashi, Toru, Masuko, Masayoshi, Matsumoto, Takuro, Wano, Yuji, Shichishima, Tsutomu, Shibayama, Hirohiko, Hase, Masakazu, Li, Lan, Johnson, Krista, Lazarowski, Alberto, Tamburini, Paul, Inazawa, Johji, Kinoshita, Taroh, Kanakura, Yuzuru

“…Patients with paroxysmal nocturnal hemoglobinuria who had a poor response to eculizumab therapy were found to have a genetic polymorphism in C5 that prevents…”
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S181: THE PHASE III, RANDOMIZED COMMODORE 2 TRIAL: RESULTS FROM A MULTICENTER STUDY OF CROVALIMAB VS ECULIZUMAB IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) PATIENTS NAIVE TO COMPLEMENT INHIBITORS by Röth, Alexander, He, Guangsheng, Brodsky, Andres, Chai‐Adisaksopha, Chatree Chatree, Dumagay, Teresita, Demichelis, Roberta, Höglund, Martin, Kelly, Richard, Lee, Je‐Hwan, Nishimura, Jun‐Ichi, Obara, Naoshi, Risitano, Antonio Maria, Gaya, Anna, Appius, Anita, Gentile, Brittany, Negricea, Raluca, Zhang, Zilu, Buatois, Simon, Han, Bing

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Apoptotic synergism between STI571 and the farnesyl transferase inhibitor SCH66336 on an imatinib-sensitive cell line by Brodsky, Andres L.

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Sudden sensorineural hearing loss as a manifestation of primary antiphospholipid syndrome by Cavallasca, Javier A, Nasswetter, Gustavo G, Gutierrez, Diego M, Bercellini, Esteban A, Brodsky, Andres L

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DELAYED ERYTHROID AND PLATELET RESPONSE TO ECULIZUMAB IN PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA – A CASE REPORT AND LITERATURE REVIEW by Andres L. Brodsky, Laura B. Colin

“…Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal disorder of haemopoiesis characterised by haemolytic anaemia, thrombophilia and variable…”
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Long‐term safety and efficacy of ravulizumab in patients with paroxysmal nocturnal hemoglobinuria: 2‐year results from two pivotal phase 3 studies by Griffin, Morag, Langemeijer, Saskia, Kulagin, Alexander, Ogawa, Masayo, Yu, Ji, Peffault de Latour, Régis, Latypova, Aigul, Barcellini, Wilma, Barraco, Fiorenza, Beam, Donald, Bettelheim, Peter, Brodsky, Andres, Carnley, Benedict, Cermak, Jaroslav, Chen, Tsai‐Yun, Chew, Lee Ping, Choi, Chul Won, De Guibert, Sophie, Devos, Timothy, Dunaev, Yuri, Dwilewicz‐Trojaczek, Jadwiga, Edahiro, Yoko, Elykomov, Iliya, Engelberger, Maria Ines, Pomponi, Fabrizio, Fuereder, Wolfgang, Fujii, Nobuharu, Fujiwara, Shinichiro, Girault, Stéphane, Gomez Almaguer, David, Gritsaev, Sergey, Hantaweepant, Chattree, Harada, Hiroshi, Höglund, Martin, Husin, Azlan, Ikezoe, Takayuki, Ishiyama, Ken, Jang, Jun Ho, Jo, Deog‐Yeon, Kang, Ka‐Won, Kennedy, James, Kim, Hyo Jung, Kim, Jeong‐A, Kim, Jin Seok, Kimura, Fumihiko, Kosugi, Hiroshi, Kulagin, Alexander, Kulasekararaj, Austin, Lai, Kuan‐Ming, Lee, Gyeong‐Won, Lee, Jae Hoon, Lee, Je‐Hwan, Lee, Jong Wook, Lin, Chien‐Chin, Martynova, Elena, Matsumura, Itaru, Meike, Galina, Menosi Gualandro, Sandra Fátima, Mori, Yasuo, Morita, Kimio, Morselli Ramalho, Fernanda Maria, Muus, Petra, Myasnikov, Alexander, Naito, Kensuke, Ninomiya, Haruhiko, Notaro, Rosario, Okada, Masaya, Okamoto, Shinichiro, Olkhovik, Tatiana, Paquette, Ronald, Park, Joon Seong, Peffault de la Tour, Régis, Piatek, Caroline, Piekarska, Agnieszka, Pospelova, Tatiana, Rojnuckarin, Ponlapat, Rosa Pessoa, Viviani de Lourdes, Rossi, Blanca, Salvino de Araujo, Marco Aurelio, Samuel, Desmond, Shatokhin, Yury, Shelekhova, Tatiana, Sohn, Sang Kyun, Sunami, Kazutaka, Syed Abdul Kadir, Sharifah Shahnaz, Toh, See Guan, Tomita, Akihiro, Torregrosa Diaz, José Miguel, Ueda, Yasutaka, Usuki, Kensuke, Viboonjuntra, Pongtep, Viigimaa, Iige, Volkova, Svetlana, Won, Jong‐Ho, Wong, Lily Lee Lee, Wong, Voon Fei, Yap, Eng Soo, Yeh, Su‐Peng, Yhim, Ho‐Young, Zhuravkov, Andrey

“…Objectives The complement component 5 (C5) inhibitor ravulizumab demonstrated non‐inferiority to eculizumab following 26 weeks of treatment in complement…”
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Phase 3 randomized COMMODORE 2 trial: Crovalimab versus eculizumab in patients with paroxysmal nocturnal hemoglobinuria naive to complement inhibition by Röth, Alexander, He, Guangsheng, Tong, Hongyan, Lin, Zenghua, Wang, Xiaoqin, Chai‐Adisaksopha, Chatree, Lee, Je‐Hwan, Brodsky, Andres, Hantaweepant, Chattree, Dumagay, Teresita E., Demichelis‐Gómez, Roberta, Rojnuckarin, Ponlapat, Sun, Jing, Höglund, Martin, Jang, Jun Ho, Gaya, Anna, Silva, Fernando, Obara, Naoshi, Kelly, Richard J., Beveridge, Leigh, Buatois, Simon, Chebon, Sammy, Gentile, Brittany, Lundberg, Pontus, Sreckovic, Sasha, Nishimura, Jun‐ichi, Risitano, Antonio, Han, Bing

“…Crovalimab is a novel C5 complement inhibitor that enables rapid and sustained C5 inhibition with subcutaneous, low‐volume self‐administration every 4 weeks…”
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Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation by Brodsky, Andrés, Mazzocchi, Octavio, Sánchez, Fabiana, Khursigara, Gus, Malhotra, Suneil, Volpacchio, Mariano

“…Paroxysmal nocturnal hemoglobinuria (PNH) is a progressive, life-threatening disorder characterized by chronic intravascular hemolysis caused by uncontrolled…”
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Eculizumab Treatment of Paroxysmal Nocturnal Hemoglobinuria Relapsing After Bone Marrow Transplant and Subsequent Clonal: Case Report by Brodsky, Andres L., Velez, Brenner Sabando, Ragusin, Curutchet

“…Abstract 5274 Paroxysmal nocturnal hemoglobinuria (PNH) is a chronic and life-threatening hematopoietic stem cell disorder characterized by deficiency of the…”
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Ham Test For Therapeutic Monitoring Of Eculizumab In Paroxysmal Nocturnal Hemoglobinuria by Arcavi, Miriam, Ceballo, Fernanda, Brodsky, Andres L., Halperin, Nora Silvia, Cantenys, Norma, Colin, Laura Beatriz, Malusardi, Cecilia, Lazarowski, Alberto

“…Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired clonal disease, caused by an inactivating mutation in the PIG-A gene in a hematopoietic stem cell…”
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"M3-M6" Molecular Response Evolution As Early Predictor of Outcome Considering Generic Vs Branded TKIs for Chronic Myeloid Leukemia (CML): An Argentine Multicentric Study by Giere, Isabel Amanda, Mela Osorio, María Jose, Klosowski, Federico Andrés, Debus, Mariana, Sackmann, Federico, Pavlovsky, Miguel A, Fernandez, Isolda, Moiraghi, Elena Beatriz, Varela, Ana Inés, Perez, Mariel Ana, Pose Cabarcos, Julio M., Bendek, Georgina, Mariano, Romina, Palmer, Silvina, Enrico, Alicia, Annetta, Isabel Cristina, Brodsky, Andres L., Intile, Dante, Pavlovsky, Carolina

“…Introduction: Early reduction of BCR-ABL transcript level has been associated with improved outcomes in CML treatment. Inability to achieve early molecular…”
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Eculizumab Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH). the Argentinian Experience by Brodsky, Andres L., Touliet, Valeria Soledad, Rocaspana, Adriana, Aldunate, Ximena, Alzueta, Abel Esteban, Barraza, Teresa, Beguelin, Raul, Campregher, Gabriel, Colin, Laura Beatriz, Dinardo, Pablo, Gotta, Daniel, Oliveira, Natalia, Parodi, Claudia, Perinotto, Gabriela, Ramirez, Mario, Rigada, Guillermina, Ronzzetti, Rosanna, Esther, Rosenfeld, Blanca, Rossi, Stivel, Miriam, Zirone, Sandra

“…paroxysmal nocturnal hemoglobinuria (PNH) is a clonal, non malignant disease of hematopoiesis characterized by intravascular hemolysis, a variable depth of…”
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Rapid desensitization and slow recovery of the cyclic AMP response mediated by histamine H2 receptors in the U937 cell line by LEMOS LEGNAZZI, B, SHAYO, C, MONCZOR, F, MARTIN, M. E, FERNANDEZ, N, BRODSKY, A, BALDI, A, DAVIO, C

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Coversin is effective in the treatment of PNH with resistance to eculizumab due to complement C5 polymorphism by Muus, Petra, Weston-Davies, Wynne, Brodsky, Andrés, Rossi, Mili, Nunn, Miles A, Mackie, Ian, Blijlevens, Nicole, Nijziel, Marten, Machin, Samuel, Langemeijer, Saskia

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Rapid desensitization and slow recovery of the cyclic AMP response mediated by histamine H 2 receptors in the U937 cell line by Lemos Legnazzi, Bibiana, Shayo, Carina, Monczor, Federico, Martin, Maria E, Fernandez, Natalia, Brodsky, Andres, Baldi, Alberto, Davio, Carlos

“…The present study focused on the desensitization process of the H 2 receptor in U937 cells and the recovery of the cyclic AMP (cAMP) response. Treatment of…”
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Histamine modulates the expression of c-fos through cyclic AMP production via the H2 receptor in the human promonocytic cell line U937 by Shayo, C, Davio, C, Brodsky, A, Mladovan, A G, Legnazzi, B L, Rivera, E, Baldi, A

“…We examined the effects of histamine and its agonists on the expression of the c-fos and c-myc proto-oncogenes at the transcriptional and translational levels…”
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Feno-genotipificación de trombocitopenias hereditarias: nuestra experiencia en 50 familias by Bonacorso, Silvina, Gomez, Silvina, Veber, Ernesto, Bazack, Nora, Marta, Rosana F, Castro Ríos, Miguel, Baroni Pietto, María C, Donato, Hugo, Cosentini, María L, Lagrotta, Pablo, Glembotsky, Ana Claudia, Marti, Alejandra, Korin, Jorge D, Brodsky, Andrés, Goette, Nora P, Altuna, Diana R, Heller, Paula G, Ayala, Daniela, Arrieta, María E, Ponzinibbio, Carlos, Arbesú, Guillermo, Guglielmone, Hugo, Rapetti, María C, Zerga, Marta E, Marin Oyarzún, Cecilia P, Negro, Fernando, Savoia, Anna, Molinas, Felisa C, Pecci, Alessandro, Basquiera, Ana L, Rosso, Diego

“…Diagnosis of inherited thrombocytopenias represents a true challenge owing to heterogeneity of these disorders and the absence of distinctive features in…”
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Sudden sensorineural hearing loss as a manifestation of primary antiphospholipid syndrome by Cavallasca, Javier A, Nasswetter, Gustavo G, Gutierrez, Diego M, Bercellini, Esteban A, Brodsky, Andres L

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MANAGEMENT RECOMMENDATIONS FOR DIRECT ORAL ANTICOAGULANTS (DOACs) ANTI Xa AND ANTI IIa by Ceresetto, José M, Tajer, Carlos, Duboscq, Cristina, Bottaro, Federico, Casais, Patricia, Korin, Jorge, Fondevila, Carlos, Giumelli, Carla, Scazziota, Alejandra, Rossi, Andrea, Botto, Fernando, Ariscancela, Maria Ester, Martinuzzo, Marta, Zaidel, Ezequiel, Fitz Maurice, Mario, Bahit, Cecilia, Vazquez, Fernando, Molnar, Soledad, Saizberg, Simón, Negri Aranguren, Pedro, Rosa, Claudio, Fedele, José Luis, Comignani, Pablo, Pombo, Gonzalo, Raña, Pablo, Adamczuk, Yolanda, Martí, Alejandra, Charask, Adrián, Penchasky, Diana, Riveros, Dardo, Mariani, Javier, Puente, Dolores, Celebrin, Lucia, Bosio, Martín, Brodsky, Andrés, Sanchez Lucero, Analía, Castillo Costa, Yanina, Hirschson, Alfredo, Arbesú, Guillermo, Viñuales, Susana, Kazelian, Lucía, Maneyro, Alberto, Gutierrez, Victoria, Castro Rios, Miguel, Gagliardi, Juan, Lescano, Adrián, Repetto, Fernanda

“…Direct oral anticoagulants have emerged as the drugs that have changed the management of the antithrombotic treatment in the last 15 years. Their advantages,…”
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Forskolin induces U937 cell line differentiation as a result of a sustained cAMP elevation by Brodsky, Andrés, Davio, Carlos, Shayo, Carina, Lemos Legnazzi, Bibiana, Barbosa, Marcos, Lardo, Mabel, Morelli, Adrián, Baldi, Alberto, Sanchez Avalos, Julio César, Rivera, Elena

“…The present study examines the effects of forskolin on U937 cell differentiation. We recently reported that dibutyryl cAMP (dbcAMP), but not cAMP-elevating…”
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