Search Results - "Brodin, Patrik"

Revisiting the dose constraints for head and neck OARs in the current era of IMRT by Brodin, N.Patrik, Tomé, Wolfgang A.

“…•Xerostomia: QUANTEC constraints for parotid glands validated in independent cohorts.•Dysphagia: Limit larynx V50 <27% or Dmean <40 Gy, and mid- and sup-PCM…”
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Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury by Saha, Subhrajit, Aranda, Evelyn, Hayakawa, Yoku, Bhanja, Payel, Atay, Safinur, Brodin, N Patrik, Li, Jiufeng, Asfaha, Samuel, Liu, Laibin, Tailor, Yagnesh, Zhang, Jinghang, Godwin, Andrew K., Tome, Wolfgang A., Wang, Timothy C., Guha, Chandan, Pollard, Jeffrey W.

“…WNT/β-catenin signalling is crucial for intestinal homoeostasis. The intestinal epithelium and stroma are the major source of WNT ligands but their origin and…”
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Life years lost—comparing potentially fatal late complications after radiotherapy for pediatric medulloblastoma on a common scale by Brodin, N. Patrik, Vogelius, Ivan R., Maraldo, Maja V., Munck af Rosenschöld, Per, Aznar, Marianne C., Kiil‐Berthelsen, Anne, Nilsson, Per, Björk‐Eriksson, Thomas, Specht, Lena, Bentzen, Søren M.

“…BACKGROUND: The authors developed a framework for estimating and comparing the risks of various long‐term complications on a common scale and applied it to 3…”
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Hepatocellular Carcinoma in HIV-Infected Patients: Clinical Presentation and Outcomes in a Racially Diverse Urban Population by D’Aiello, Angelica, Rahman, Numa, Patrik Brodin, N., Dave, Manish, Jasra, Sakshi, Kaubisch, Andreas, Kabarriti, Rafi, Chuy, Jennifer

“…Purpose As life expectancy for HIV patients improve, hepatocellular carcinoma (HCC) has become a non-AIDS defining illness with a high impact on morbidity and…”
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Using CT-guided stereotactic prostate radiation therapy (CT-SPRT) to assess sustained murine prostate ablation by Zahalka, Ali H., Brodin, N. Patrik, Maryanovich, Maria, Wang, Xizhe, Watts, Kara L., Pinho, Sandra, Guha, Chandan, Frenette, Paul S.

“…The prostate is a hormone-responsive organ where testicular androgens drive the proliferation and survival of prostatic cells, ensuring the development and…”
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Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression by Wei, Qiaozhi, Nakahara, Fumio, Asada, Noboru, Zhang, Dachuan, Gao, Xin, Xu, Chunliang, Alfieri, Alan, Brodin, N. Patrik, Zimmerman, Samuel E., Mar, Jessica C., Guha, Chandan, Guo, Wenjun, Frenette, Paul S.

“…Bone marrow (BM) mesenchymal stem and progenitor cells (MSPCs) are a critical constituent of the hematopoietic stem cell (HSC) niche. Previous studies have…”
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Minimizing Late Effects for Patients With Mediastinal Hodgkin Lymphoma: Deep Inspiration Breath-Hold, IMRT, or Both? by Aznar, Marianne C., PhD, Maraldo, Maja V., MD, PhD, Schut, Deborah A., BSc, Lundemann, Michael, MSc, Brodin, N Patrik, PhD, Vogelius, Ivan R., PhD, Berthelsen, Anne K., MD, PhD, Specht, Lena, MD, DSc, Petersen, Peter M., MD, PhD

“…Purpose Hodgkin lymphoma (HL) survivors have an increased risk of cardiovascular disease (CD), lung cancer, and breast cancer. We investigated the risk for the…”
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The risk of late effects following pediatric and adult radiotherapy regimens in Hodgkin lymphoma by Lundgaard, Anni Young, Hjalgrim, Lisa Lyngsie, Rechner, Laura Ann, Lundemann, Michael, Brodin, N. Patrik, Joergensen, Morten, Specht, Lena, Maraldo, Maja Vestmoe

“…Purpose Adolescent young adults (AYA) with Hodgkin lymphoma (HL) are treated according to either pediatric or adult protocols, however, the best strategy has…”
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Hybrid tandem and ovoids brachytherapy in locally advanced cervical cancer: impact of dose and tumor volume metrics on outcomes by Rivera, Amanda, Wassel, Monica, Brodin, Patrik N, Yaparpalvi, Ravindra, Velten, Christian, Kabarriti, Rafi, Garg, Madhur, Kalnicki, Shalom, Mehta, Keyur J

“…To report the impact of dose and tumor volume metrics at brachytherapy on outcomes for locally advanced cervical cancer treated with tandem and ovoids…”
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Radiobiological risk estimates of adverse events and secondary cancer for proton and photon radiation therapy of pediatric medulloblastoma by Brodin, N Patrik, Munck Af Rosenschöld, Per, Aznar, Marianne C, Kiil-Berthelsen, Anne, Vogelius, Ivan R, Nilsson, Per, Lannering, Birgitta, Björk-Eriksson, Thomas

“…The aim of this model study was to estimate and compare the risk of radiation-induced adverse late effects in pediatric patients with medulloblastoma (MB)…”
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Individualized quality of life benefit and cost-effectiveness estimates of proton therapy for patients with oropharyngeal cancer by Brodin, N Patrik, Kabarriti, Rafi, Schechter, Clyde B, Pankuch, Mark, Gondi, Vinai, Kalnicki, Shalom, Garg, Madhur K, Tomé, Wolfgang A

“…Proton therapy is a promising advancement in radiation oncology especially in terms of reducing normal tissue toxicity, although it is currently expensive and…”
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Hippocampal-dependent neurocognitive impairment following cranial irradiation observed in pre-clinical models: current knowledge and possible future directions by Tomé, Wolfgang A, Gökhan, Şölen, Gulinello, Maria E, Brodin, N Patrik, Heard, John, Mehler, Mark F, Guha, Chandan

“…We reviewed the literature for studies pertaining to impaired adult neurogenesis leading to neurocognitive impairment following cranial irradiation in rodent…”
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Fatigue in Patients With Head and Neck Cancer Treated With Radiation Therapy: A Prospective Study of Patient-Reported Outcomes and Their Association With Radiation Dose to the Cerebellum by Abel, Edvard, Silander, Ewa, Nordström, Fredrik, Olsson, Caroline, Brodin, N. Patrik, Nyman, Jan, Björk-Eriksson, Thomas, Hammerlid, Eva

“…Although fatigue is a known side effect in patients with head and neck cancer (HNC) receiving radiation therapy, knowledge regarding long-term fatigue and…”
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Residual positioning errors and uncertainties for pediatric craniospinal irradiation and the impact of image guidance by Gram, Daniel, Haraldsson, André, Brodin, N Patrik, Nysom, Karsten, Björk-Eriksson, Thomas, Munck Af Rosenschöld, Per

“…Optimal alignment is of utmost importance when treating pediatric patients with craniospinal irradiation (CSI), especially with regards to field junctions and…”
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A Model for Precise and Uniform Pelvic- and Limb-Sparing Abdominal Irradiation to Study the Radiation-Induced Gastrointestinal Syndrome in Mice Using Small Animal Irradiation Systems by Brodin, N. Patrik, Velcich, Anna, Guha, Chandan, Tomé, Wolfgang A.

“…Background and Purpose: Currently, no readily available mitigators exist for acute abdominal radiation injury. Here, we present an animal model for precise and…”
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Hippocampal sparing radiotherapy for pediatric medulloblastoma: impact of treatment margins and treatment technique by Brodin, N Patrik, Munck af Rosenschöld, Per, Blomstrand, Malin, Kiil-Berthlesen, Anne, Hollensen, Christian, Vogelius, Ivan R, Lannering, Birgitta, Bentzen, Søren M, Björk-Eriksson, Thomas

“…We investigated how varying the treatment margin and applying hippocampal sparing and proton therapy impact the risk of neurocognitive impairment in pediatric…”
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A Retrospective Evaluation of the Benefit of Referring Pediatric Cancer Patients to an External Proton Therapy Center by Munck af Rosenschold, Per, Engelholm, Svend A., Brodin, Patrik N., Jørgensen, Morten, Grosshans, David R., Zhu, Ronald X., Palmer, Matthew, Crawford, Cody N., Mahajan, Anita

“…Background Pediatric cancer patients requiring radiation therapy (RT) have been routinely assessed and referred to proton therapy (PT) at an external…”
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Dosimetry Formalism and Implementation of a Homogenous Irradiation Protocol to Improve the Accuracy of Small Animal Whole-Body Irradiation Using a 137Cs Irradiator by Brodin, N Patrik, Chen, Yong, Yaparpalvi, Ravindra, Guha, Chandan, Tomé, Wolfgang A

“…ABSTRACTShielded Cs irradiators are routinely used in pre-clinical radiation research to perform in vitro or in vivo investigations. Without appropriate…”
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Comparing outcomes following total neoadjuvant therapy and following neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer by Zhu, Shaoyu, Brodin, N. Patrik, English, Keara, Ohri, Nitin, Chuy, Jennifer W., Rajdev, Lakshmi N., Narang, Rahul, Kalnicki, Shalom, Guha, Chandan, Garg, Madhur K., Kabarriti, Rafi

“…There is recent interest in treating locally advanced rectal cancer (LARC) patients with total neoadjuvant therapy (TNT). However, whether TNT is associated…”
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1166 Preclinical evaluation of lintuzumab-Ac225, a CD33 antibody radioconjugate targeting myeloid-derived suppressor cells by Chin, Amanda, Chen, Mary, Lewis, Debbie, Mukherjee, Sumit, Li, Jason, Xu, Le-Cun, Roy, Monideepa, Brodin, Patrik, Touw, William van der, Beckford-Vera, Denis, Kotanides, Helen

“…BackgroundMyeloid-derived suppressor cells (MDSCs) are immunosuppressive myeloid lineage cells enriched in cancer patients. There is growing interest in the…”
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