Search Results - "Brodie, Scott E"
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Efficacy and Toxicity of Intravitreous Chemotherapy for Retinoblastoma: Four-Year Experience
Published in Ophthalmology (Rochester, Minn.) (01-04-2017)“…Purpose To investigate the efficacy and toxicity of intravitreous melphalan for treatment of retinoblastoma, as a single agent or with concomitant topotecan…”
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Intravitreal chemotherapy in retinoblastoma: expanded use beyond intravitreal seeds
Published in British journal of ophthalmology (01-04-2019)“…Ophthalmic artery chemosurgery (OAC) has changed the face of retinoblastoma treatment and led to a higher rate of globe salvage. The introduction of…”
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Intra-Arterial Chemotherapy (Ophthalmic Artery Chemosurgery) for Group D Retinoblastoma
Published in PloS one (12-01-2016)“…To report globe salvage rates, patient survival and adverse events of ophthalmic artery chemosurgery (OAC) for International Classification of Retinoblastoma…”
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Superselective Ophthalmic Artery Chemotherapy as Primary Treatment for Retinoblastoma (Chemosurgery)
Published in Ophthalmology (Rochester, Minn.) (01-08-2010)“…Purpose To report on our 3-year experience with the use of superselective ophthalmic artery infusion of chemotherapy as initial, primary treatment for…”
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Current Treatment of Bilateral Retinoblastoma: The Impact of Intraarterial and Intravitreous Chemotherapy
Published in Neoplasia (New York, N.Y.) (01-08-2018)“…PURPOSE: To evaluate the management and outcomes of naïve bilateral retinoblastoma treated at a single-center over a 5-year period during the era of ophthalmic…”
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Comparison of efficacy and toxicity of intravitreal melphalan formulations for retinoblastoma
Published in PloS one (01-07-2020)“…Objective Intravitreal melphalan injections are commonly used in the treatment for intraocular retinoblastoma. This study compares retinal toxicity and ocular…”
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Simultaneous Bilateral Ophthalmic Artery Chemosurgery for Bilateral Retinoblastoma (Tandem Therapy)
Published in PloS one (03-06-2016)“…Report on the 7-year experience with bilateral ophthalmic artery chemosurgery (OAC-Tandem therapy) for bilateral retinoblastoma. Retrospective, single…”
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Combined, sequential intravenous and intra-arterial chemotherapy (bridge chemotherapy) for young infants with retinoblastoma
Published in PloS one (18-09-2012)“…Intra-arterial (i.a.) chemotherapy has more risks of procedural complications in neonates and young infants. For these reasons, we have developed a strategy of…”
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Risk factors for severe neutropenia following intra-arterial chemotherapy for intra-ocular retinoblastoma
Published in PloS one (10-10-2014)“…Intra-arterial chemotherapy is a promising strategy for intra-ocular retinoblastoma. Neutropenia is the most commonly encountered systemic toxicity and in this…”
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Efficacy and Toxicity of Second-Course Ophthalmic Artery Chemosurgery for Retinoblastoma
Published in Ophthalmology (Rochester, Minn.) (01-05-2015)“…Objective Assess the usefulness of second-course ophthalmic artery chemosurgery (OAC) for patients with intraocular retinoblastoma that recurred after prior…”
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Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: five year review
Published in PloS one (24-04-2012)“…Ophthalmic artery chemosurgery (OAC) for retinoblastoma was introduced by us 5 years ago for advanced intraocular retinoblastoma. Because the success was…”
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A clinically viable approach to restoring visual function using optogenetic gene therapy
Published in Molecular therapy. Methods & clinical development (08-06-2023)“…Optogenetic gene therapies offer a promising strategy for restoring vision to patients with retinal degenerative diseases, such as retinitis pigmentosa (RP)…”
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Carboplatin +/- topotecan ophthalmic artery chemosurgery for intraocular retinoblastoma
Published in PloS one (21-08-2013)“…Carboplatin administered systemically or periocularly can result in dramatic and prompt regression of retinoblastoma. However, both routes are rarely curative…”
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Total retinal detachments due to retinoblastoma: Outcomes following intra-arterial chemotherapy/ophthalmic artery chemosurgery
Published in PloS one (26-04-2018)“…To report on the rate and timing of retinal reattachment and outcomes for retinoblastoma children who have total retinal detachments at presentation to our…”
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Electroretinogram monitoring of dose-dependent toxicity after ophthalmic artery chemosurgery in retinoblastoma eyes: six year review
Published in PloS one (20-01-2014)“…To report electroretinogram responses of retinoblastoma children under anesthesia before and after treatment with chemotherapeutic drugs (melphalan, topotecan,…”
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Bilateral exudative retinal detachments after subretinal gene therapy with voretigene neparvovec-rzyl for RPE65 Leber Congenital Amaurosis
Published in American journal of ophthalmology case reports (01-12-2023)“…To report panuveitis with exudative retinal detachments in a healthy 27-year-old woman with biallelic mutations in the RPE65 gene, who underwent bilateral…”
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CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice
Published in Cell (10-12-1999)“…Oligodendrocyte-specific protein (OSP)/claudin-11 is a recently identified transmembrane protein found in CNS myelin and testis with unknown function. Herein…”
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Ophthalmic Artery Chemosurgery for Retinoblastoma Prevents New Intraocular Tumors
Published in Ophthalmology (Rochester, Minn.) (01-03-2013)“…Objective To determine the incidence and timing of new intraocular tumor foci in genetic retinoblastoma cases after treatment with ophthalmic artery…”
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Salvage/Adjuvant Brachytherapy After Ophthalmic Artery Chemosurgery for Intraocular Retinoblastoma
Published in International journal of radiation oncology, biology, physics (01-11-2013)“…Purpose To evaluate the efficacy and toxicity of brachytherapy after ophthalmic artery chemosurgery (OAC) for retinoblastoma. Methods and Materials This was a…”
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ISCEV guide to visual electrodiagnostic procedures
Published in Documenta ophthalmologica (01-02-2018)“…Clinical electrophysiological testing of the visual system incorporates a range of noninvasive tests and provides an objective indication of function relating…”
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