Search Results - "Broderick, Joseph P"

Evolution of the Modified Rankin Scale and Its Use in Future Stroke Trials by Broderick, Joseph P, Adeoye, Opeolu, Elm, Jordan

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Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening by Brown, Robert D, Prof, Broderick, Joseph P, Prof

“…Summary Intracranial saccular or berry aneurysms are common, occurring in about 1–2% of the population. Unruptured intracranial aneurysms are increasingly…”
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Advances in the management of intracerebral hemorrhage by Adeoye, Opeolu, Broderick, Joseph P

“…Intracerebral hemorrhage (ICH) carries a high risk of morbidity or death, and no effective therapies are available to combat this condition. In this article,…”
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Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the Interventional Management of Stroke (IMS III) phase 3 trial by Khatri, Pooja, Prof, Yeatts, Sharon D, PhD, Mazighi, Mikael, MD, Broderick, Joseph P, Prof, Liebeskind, David S, Prof, Demchuk, Andrew M, Prof, Amarenco, Pierre, Prof, Carrozzella, Janice, MSN, Spilker, Judith, BSN, Foster, Lydia D, PhD, Goyal, Mayank, Prof, Hill, Michael D, Prof, Palesch, Yuko Y, Prof, Jauch, Edward C, Prof, Haley, E Clarke, Prof, Vagal, Achala, MD, Tomsick, Thomas A, Prof

“…Summary Background The IMS III trial did not show a clinical benefit of endovascular treatment compared with intravenous alteplase (recombinant tissue…”
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The AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke randomized trial: Rationale and methods by Kamel, Hooman, Longstreth, WT, Tirschwell, David L, Kronmal, Richard A, Broderick, Joseph P, Palesch, Yuko Y, Meinzer, Caitlyn, Dillon, Catherine, Ewing, Irene, Spilker, Judith A, Di Tullio, Marco R, Hod, Eldad A, Soliman, Elsayed Z, Chaturvedi, Seemant, Moy, Claudia S, Janis, Scott, Elkind, Mitchell SV

“…Rationale Recent data suggest that a thrombogenic atrial substrate can cause stroke in the absence of atrial fibrillation. Such an atrial cardiopathy may…”
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Collaterals at Angiography and Outcomes in the Interventional Management of Stroke (IMS) III Trial by LIEBESKIND, David S, TOMSICK, Thomas A, ZAIDAT, Osama O, HUSSAIN, Syed I, GOYAL, Mayank, MENON, Bijoy K, FIRAS AL ALI, YAN, Bernard, PALESCH, Yuko Y, BRODERICK, Joseph P, FOSTER, Lydia D, YEATTS, Sharon D, CARROZZELLA, Janice, DEMCHUK, Andrew M, JOVIN, Tudor G, KHATRI, Pooja, VON KUMMER, Ruediger, SUGG, Rebecca M

“…Endovascular strategies provide unique opportunity to correlate angiographic measures of collateral circulation at the time of endovascular therapy. We…”
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Carotid artery stenosis as a cause of stroke by Flaherty, Matthew L, Kissela, Brett, Khoury, Jane C, Alwell, Kathleen, Moomaw, Charles J, Woo, Daniel, Khatri, Pooja, Ferioli, Simona, Adeoye, Opeolu, Broderick, Joseph P, Kleindorfer, Dawn

“…Population-based studies have estimated that about 15% of ischemic strokes are caused by large-vessel cerebrovascular disease. We determined the types of…”
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Advances and challenges in treatment and prevention of ischemic stroke by Grossman, Aaron W., Broderick, Joseph P.

“…We review recent advances in the treatment and prevention of acute ischemic stroke, including the current state of endovascular therapy, in light of 5…”
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Individual Patient Data Subgroup Meta-Analysis of Surgery for Spontaneous Supratentorial Intracerebral Hemorrhage by GREGSON, Barbara A, BRODERICK, Joseph P, ZUCCARELLO, Mario, DAVID MENDELOW, A, AUER, Ludwig M, BATJER, Hunt, CHEN, Xian-Cheng, JUVELA, Seppo, MORGENSTERN, Lewis B, PANTAZIS, George C, TEERNSTRA, Onno P. M, WANG, Wen-Zhi

“…By 2010 there had been 14 published trials of surgery for intracerebral hemorrhage reported in systematic reviews or to the authors, but the role and timing of…”
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Stable incidence but declining case-fatality rates of subarachnoid hemorrhage in a population by Mackey, Jason, Khoury, Jane C, Alwell, Kathleen, Moomaw, Charles J, Kissela, Brett M, Flaherty, Matthew L, Adeoye, Opeolu, Woo, Daniel, Ferioli, Simona, De Los Rios La Rosa, Felipe, Martini, Sharyl, Khatri, Pooja, Broderick, Joseph P, Zuccarello, Mario, Kleindorfer, Dawn

“…OBJECTIVE:To characterize temporal trends in subarachnoid hemorrhage (SAH) incidence and outcomes over 5 time periods in a large population-based stroke study…”
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Recanalization and clinical outcome of occlusion sites at baseline CT angiography in the Interventional Management of Stroke III trial by Demchuk, Andrew M, Goyal, Mayank, Yeatts, Sharon D, Carrozzella, Janice, Foster, Lydia D, Qazi, Emmad, Hill, Michael D, Jovin, Tudor G, Ribo, Marc, Yan, Bernard, Zaidat, Osama O, Frei, Donald, von Kummer, Rüdiger, Cockroft, Kevin M, Khatri, Pooja, Liebeskind, David S, Tomsick, Thomas A, Palesch, Yuko Y, Broderick, Joseph P

“…To use baseline computed tomographic (CT) angiography to analyze imaging and clinical end points in an Interventional Management of Stroke III cohort to…”
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Gene expression in peripheral immune cells following cardioembolic stroke is sexually dimorphic by Stamova, Boryana, Jickling, Glen C, Ander, Bradley P, Zhan, Xinhua, Liu, DaZhi, Turner, Renee, Ho, Carolyn, Khoury, Jane C, Bushnell, Cheryl, Pancioli, Arthur, Jauch, Edward C, Broderick, Joseph P, Sharp, Frank R

“…Epidemiological studies suggest that sex has a role in the pathogenesis of cardioembolic stroke. Since stroke is a vascular disease, identifying sexually…”
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Evaluation of Interval Times From Onset to Reperfusion in Patients Undergoing Endovascular Therapy in the Interventional Management of Stroke III Trial by Goyal, Mayank, Almekhlafi, Mohammed A, Fan, Liqiong, Menon, Bijoy K, Demchuk, Andrew M, Yeatts, Sharon D, Hill, Michael D, Tomsick, Thomas, Khatri, Pooja, Zaidat, Osama O, Jauch, Edward C, Eesa, Muneer, Jovin, Tudor G, Broderick, Joseph P

“…BACKGROUND—Meaningful delays occurred in the Interventional Management of Stroke (IMS) III trial. Analysis of the work flow will identify factors contributing…”
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Factors Associated With Premature Termination of Hyperacute Stroke Trials: A Review by Aziz, Yasmin N, Sucharew, Heidi, Reeves, Mathew J, Broderick, Joseph P

“…We performed a review of acute stroke trials to determine features associated with premature termination of trial enrollment, defined by the authors as not…”
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Combined Approach to Lysis Utilizing Eptifibatide and Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke-Full Dose Regimen Stroke Trial by Adeoye, Opeolu, Sucharew, Heidi, Khoury, Jane, Vagal, Achala, Schmit, Pamela A., Ewing, Irene, Levine, Steven R., Demel, Stacie, Eckerle, Bryan, Katz, Brian, Kleindorfer, Dawn, Stettler, Brian, Woo, Daniel, Khatri, Pooja, Broderick, Joseph P., Pancioli, Arthur M.

“…BACKGROUND AND PURPOSE—The Combined Approach to Lysis Utilizing Eptifibatide and Recombinant Tissue-Type Plasminogen Activator (r-tPA; CLEAR) in Acute Ischemic…”
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Density and Shape as CT Predictors of Intracerebral Hemorrhage Growth by BARRAS, Christen D, TRESS, Brian M, STEINER, Thorsten, DAVIS, Stephen M, CHRISTENSEN, Soren, MACGREGOR, Lachlan, COLLINS, Marnie, DESMOND, Patricia M, SKOLNICK, Brett E, MAYER, Stephan A, BRODERICK, Joseph P, DIRINGER, Michael N

“…Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity,…”
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Bayesian selective response‐adaptive design using the historical control by Kim, Mi‐Ok, Harun, Nusrat, Liu, Chunyan, Khoury, Jane C., Broderick, Joseph P.

“…High quality historical control data, if incorporated, may reduce sample size, trial cost, and duration. A too optimistic use of the data, however, may result…”
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Incidence of seizures in the acute phase of stroke: A population‐based study by Szaflarski, Jerzy P., Rackley, Angela Y., Kleindorfer, Dawn O., Khoury, Jane, Woo, Daniel, Miller, Rosemary, Alwell, Kathleen, Broderick, Joseph P., Kissela, Brett M.

“…Summary Purpose: The incidence of seizures within 24 h of acute stroke has not been studied extensively. We aimed to establish the incidence of acute…”
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Genome-Wide Association Study of Intracranial Aneurysms Confirms Role of Anril and SOX17 in Disease Risk by FOROUD, Tatiana, KOLLER, Daniel L, MOOMAW, Charles J, HORNUNG, Richard, HUSTON, John, MEISSNER, Irene, BAILEY-WILSON, Joan E, LANGEFELD, Carl, ROULEAU, Guy, CONNOLLY, E. Sander, WORRALL, Bradford B, KLEINDORFER, Dawn, DONGBING LAI, FLAHERTY, Matthew L, MARTINI, Sharyl, MACKEY, Jason, DE LOS RIOS LA ROSA, Felipe, BROWN, Robert D, BRODERICK, Joseph P, SAUERBECK, Laura, ANDERSON, Craig, KO, Nerissa, DEKA, Ranjan, MOSLEY, Thomas H, FORNAGE, Myriam, WOO, Daniel

“…Genomewide association studies have identified novel genetic factors that contribute to intracranial aneurysm (IA) susceptibility. We sought to confirm…”
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Risk factors for intracerebral hemorrhage differ according to hemorrhage location by MARTINI, Sharyl R, FLAHERTY, Matthew L, BRODERICK, Joseph P, LANGEFELD, Carl D, WOO, Daniel, BROWN, W. Mark, HAVERBUSCH, Mary, COMEAU, Mary E, SAUERBECK, Laura R, KISSELA, Brett M, DEKA, Ranjan, KLEINDORFER, Dawn O, MOOMAW, Charles J

“…Risk factors have been described for spontaneous intracerebral hemorrhage (ICH); their relative contribution to lobar vs nonlobar hemorrhage location is less…”
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