Search Results - "Broderick, David"
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Bioinformatic Approaches for Describing the Oral Microbiota
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Cultivation-independent (molecular) analysis of the oral microbiota can provide a comprehensive picture of microbial community composition, yet there is an…”
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Dynamic Upper and Lower Airway Microbiotas in Paediatric Bronchiectasis Exacerbations: A Pilot Study
Published in Frontiers in cellular and infection microbiology (24-01-2022)“…Non-cystic fibrosis bronchiectasis is a respiratory health condition with many possible aetiologies, some of which are potentially reversible in childhood with…”
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Gut microbiota predicts body fat change following a low-energy diet: a PREVIEW intervention study
Published in Genome medicine (23-05-2022)“…Low-energy diets (LEDs) comprise commercially formulated food products that provide between 800 and 1200 kcal/day (3.3-5 MJ/day) to aid body weight loss…”
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Developing student social skills using restorative practices : a new framework called H.E.A.R.T
Published in Social psychology of education (01-02-2018)“…Students attending schools today not only learn about formal academic subjects, they also learn social and emotional skills. Whole-school restorative practices…”
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Embedded Mental Health in the United States Marine Corps
Published in Military medicine (18-09-2020)“…Abstract Introduction Despite the rich history and progression of mental health assets and their utilization within the Marine Corps, the implementation of…”
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Realising respiratory microbiomic meta-analyses: time for a standardised framework
Published in Microbiome (22-03-2023)“…In microbiome fields of study, meta-analyses have proven to be a valuable tool for identifying the technical drivers of variation among studies and results of…”
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Forecasting severe respiratory disease hospitalizations using machine learning algorithms
Published in BMC medical informatics and decision making (09-10-2024)“…Forecasting models predicting trends in hospitalization rates have the potential to inform hospital management during seasonal epidemics of respiratory…”
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RSV severity in New Zealand 2021 and 2022: applying the WHO severity assessment framework
Published in The Lancet regional health. Western Pacific (01-10-2024)Get full text
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Screening for Ligands of Human Retinoid X Receptor-α Using Ultrafiltration Mass Spectrometry
Published in Analytical chemistry (Washington) (15-12-2007)“…Retinoid X receptors (RXRs) function as ligand-activated transcription factors and are obligatory components of a large number of nuclear receptor…”
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Dynamics and Ligand-Induced Solvent Accessibility Changes in Human Retinoid X Receptor Homodimer Determined by Hydrogen Deuterium Exchange and Mass Spectrometry
Published in Biochemistry (Easton) (03-02-2004)“…Receptors for retinoic acid act as ligand activated transcription factors. The three-dimensional structure of the retinoid X receptor (RXR) ligand binding…”
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Bacterial Signatures of Paediatric Respiratory Disease: An Individual Participant Data Meta-Analysis
Published in Frontiers in microbiology (23-12-2021)“…The airway microbiota has been linked to specific paediatric respiratory diseases, but studies are often small. It remains unclear whether particular bacteria…”
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Equilibrium unfolding of the retinoid X receptor ligand binding domain and characterization of an unfolding intermediate
Published in Biophysical chemistry (01-04-2009)“…The retinoid X receptor (RXR) is a ligand-activated transcription factor that plays an important role in growth and development and the maintenance of cellular…”
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Lidar attitude estimation for vehicle safety systems
Published in IEEE/ION Position, Location and Navigation Symposium (01-05-2010)“…This paper presents two techniques for determining vehicle pitch and roll with a 3-D lidar which will first auto-calibrate itself to the vehicle's axes. The…”
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Anaerobic bacteria dominate the cholesteatoma tissue of chronic suppurative otitis media patients
Published in Microbial pathogenesis (01-11-2024)“…The aim of this study was to investigate both the microbial composition and absolute abundance of clinically relevant bacteria in tissue specimens from…”
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Paired qualitative and quantitative analysis of bacterial microcolonies in the tonsils of patients with tonsillar hyperplasia
Published in Microbes and infection (01-05-2024)“…The discovery of bacterial microcolonies in tonsillar tissue of patients with tonsillar hyperplasia has raised the question of their role in provoking the…”
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Comparison of the Burden and Temporal Pattern of Hospitalisations Associated With Respiratory Syncytial Virus (RSV) Before and After COVID‐19 in New Zealand
Published in Influenza and other respiratory viruses (01-07-2024)“…ABSTRACT Background Changes in the epidemiology of illnesses caused by respiratory syncytial virus (RSV) infection following the COVID‐19 pandemic are…”
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Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: Insights into the antagonism of the hypolipidemic agent Z-guggulsterone
Published in Biochimica et biophysica acta (01-09-2014)“…Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids,…”
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The airway microbiota in children newly diagnosed with bronchiectasis largely retains its diversity
Published in The European respiratory journal (01-08-2019)Get full text
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Severe Acute Respiratory Infection (SARI) due to Influenza in Post-COVID Resurgence: Disproportionate Impact on Older Māori and Pacific Peoples
Published in Influenza and other respiratory viruses (01-11-2024)“…Influenza reemerged after a 2020-2021 hiatus in 2022, but understanding the resurgence needs pre-COVID era surveillance. We compared age- and…”
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A methodological pipeline for the preclinical evaluation of novel topical agents for the treatment of CRS
Published in International forum of allergy & rhinology (01-11-2024)“…Key points Novel topical therapeutics require extensive pre‐clinical testing to assess efficacy and safety. Antibiofilm or immunosuppressant agents can utilize…”
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