Search Results - "Brockman, Simone"

The neuroimaging basis of apathy: Empirical findings and conceptual challenges by Starkstein, Sergio E., Brockman, Simone

“…Apathy, usually defined as loss of motivation, is common in both neurodegenerative conditions such as Alzheimer's disease, and acute neurological disorders…”
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Management of Depression in Parkinson's Disease: A Systematic Review by Starkstein, Sergio E., Brockman, Simone

“…Background Depression is a frequent psychiatric condition in Parkinson's disease (PD). The treatment of depression has been examined in several randomized…”
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The syndromal validity and nosological position of apathy in Parkinson's disease by Starkstein, Sergio E., Merello, Marcelo, Jorge, Ricardo, Brockman, Simone, Bruce, David, Power, Brian

“…Although apathy is among the most frequent behavioral changes in Parkinson's disease (PD), its diagnosis is still problematic, and the overlap with depression…”
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A validation study of depressive syndromes in Parkinson's disease by Starkstein, Sergio E., Merello, Marcelo, Jorge, Ricardo, Brockman, Simone, Bruce, David, Petracca, Gustavo, Robinson, Robert G.

“…The validity, sensitivity, and specificity of depressive symptoms for the diagnosis of major depression, minor depression, dysthymic disorder, and subsyndromal…”
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Diagnostic Criteria for Depression in Alzheimer Disease: A Study of Symptom Patterns Using Latent Class Analysis by Starkstein, Sergio E., M.D., Ph.D, Dragovic, Milan, Ph.D, Jorge, Ricardo, M.D, Brockman, Simone, M.A, Robinson, Robert G., M.D

“…Context Although depression in Alzheimer disease (AD) has a negative emotional and functional impact on patients and caregivers, specific criteria to diagnose…”
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Apathy Predicts More Severe Parkinsonism in Alzheimer's Disease by Starkstein, Sergio E., M.D., Ph.D, Merello, Marcelo, M.D., Ph.D, Brockman, Simone, M.A, Bruce, David, M.D, Petracca, Gustavo, M.D, Power, Brian D., M.D., Ph.D

“…Objectives Parkinsonian signs are frequent in Alzheimer disease (AD) and are associated with a faster cognitive decline, worse quality of life, and early…”
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A Randomized, Placebo-Controlled, Double-Blind Efficacy Study of Nefiracetam to Treat Poststroke Apathy by Starkstein, Sergio E., MD, PhD, Brockman, Simone, MA, Hatch, Katherine K., MA, Bruce, David G., MD, Almeida, Osvaldo P., MD, Davis, Wendy A., PhD, Robinson, Robert G., MD

“…Background To evaluate the efficacy of treatment with nefiracetam compared to placebo in poststroke apathy. Methods A parallel group, randomized,…”
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Nonsteroidal Anti‐inflammatory Use and LRRK2 Parkinson's Disease Penetrance by San Luciano, Marta, Tanner, Caroline M., Meng, Cheryl, Marras, Connie, Lang, Anthony E., Schüle, Birgitt, Langston, J. William, Corvol, Jean‐Christophe, Goldwurm, Stefano, Berg, Daniela, Tazir, Meriem, Mellick, George D., Sue, Carolyn M., Tan, Eng King, Bressman, Susan, Saunders‐Pullman, Rachel, Raymond, Deborah, Barrett, Matthew James, Cabassa, Jose, Groves, Mark, Hunt, Ann L, Lubarr, Naomi, Palmese, Christina, Sachdev, Rivka, Sarva, Harini, Shanker, Vicki, Swan, Matthew Carrington, Soto‐Valencia, Jeannie, Johannes, Brooke, Ortega, Robert, Alcalay, Roy N, Tang, Ming‐X, Santana, Helen Mejia, Orbe‐Reilly, Martha, Fahn, Stanley, Cote, Lucien, Ford, Blair, Louis, Elan, Levy, Oren, Rosado, Llency, Ruiz, Diana, Clark, Lorraine, Marder, Karen S, Corvol, Jean‐Christophe, Bonnet, Anne‐Marie, Welter, Marie‐Laure, Mesnage, Valerie, Vidailhet, Marie, Roze, Emmanuel, Lacomblez, Lucette, Grabli, David, Mart i Masso, Jose Felix, Mondragon Rezola, Elisabet, Alustiza, Ainara Estanga, Pagola, Ana Gorostidi, Pont‐Sunyer, Claustre, Rolan, Dolores Vilas, Fernandez‐Santiago, Ruben, Quintana, Maria, Maragall, Laura, Hentati, Faycal, Farrer, Matthew, Duda, John, Read, Matt, Gibson, Rachel, Sassi, Samia Ben, Zouari, Mourad, Nabli, Fatma, Aasly, Jan, Andersen, Sigrid, Bertoni, John, Carter, Julie, Elmer, Lawrence, Jimenez, Nestor Galvez, Martin, Wayne, Pahwa, Rajesh, Lyons, Kelly, Reich, Stephen, Ramos, Carmen Serrano, Wojcieszek, Joanne, Gurevich, Tanya, Shira, Anat Bar, Weisz, Mali Gana, Yasinovsky, Kira, Zalis, Maayan, Thaler, Avner, Orr‐Urtreger, Avi, Giladi, Nir, Mountain, Joanna, Mestre, Tiago, Ghate, Taneera, Singerman, Jennifer, Al Dakheel, Amaal, Connolly, Barbara S, Gasser, Thomas, Brockmann, Kathrin, Mullins, Meghan E, Northover, Carrie, Facheris, Maurizio, Fiske, Brian

“…Background The penetrance of leucine rich repeat kinase 2 (LRRK2) mutations is incomplete and may be influenced by environmental and/or other genetic factors…”
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Clinical issues in the treatment of anxiety and depression in older adults with Parkinson's disease by Pachana, Nancy A., Egan, Sarah J., Laidlaw, Ken, Dissanayaka, Nadeeka, Byrne, Gerard J., Brockman, Simone, Marsh, Rodney, Starkstein, Sergio

“…ABSTRACT A significant proportion of persons affected by Parkinson's disease (PD) are over age 65 years. Mental health issues are often less a focus of…”
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Design and validation of a new instrument to assess fear of falling in Parkinson's disease by Terroba‐Chambi, Cinthia, Bruno, Veronica, Millar‐Vernetti, Patricio, Bruce, David, Brockman, Simone, Merello, Marcelo, Starkstein, Sergio

“…Background Fear of falling may be significantly associated with falls in Parkinson's disease (PD) and may have a negative impact on quality of life…”
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Psychiatric syndromes in Parkinsonʼs disease by Starkstein, Sergio E, Brockman, Simone, Hayhow, Bradleigh D

“…PURPOSE OF REVIEWTo examine progress about relevant behavioural and psychiatric disorders in Parkinsonʼs disease, such as depression, apathy, psychosis, and…”
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Amygdala Volumetric Change Following Psychotherapy for Posttraumatic Stress Disorder by Laugharne, Jonathan, Kullack, Claire, Lee, Christopher W, McGuire, Tracy, Brockman, Simone, Drummond, Peter D, Starkstein, Sergio

“…The authors investigated the impact of eye movement desensitization and reprocessing (EMDR) and prolonged exposure (PE) on the volumes of the amygdala and…”
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Anosognosia Is a Significant Predictor of Apathy in Alzheimer's Disease by Starkstein, Sergio E, Brockman, Simone, Bruce, David, Petracca, Gustavo

“…Anosognosia and apathy are among the most common behavioral and psychological disorders of Alzheimer's disease and are significantly associated in…”
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Neuroimaging Correlates of Apathy and Depression in Alzheimer's Disease by Starkstein, Sergio E, Mizrahi, Romina, Capizzano, Aristides A, Acion, Laura, Brockman, Simone, Power, Brian D

“…A consecutive series of 79 patients with probable Alzheimer's disease were assessed with a structured psychiatric evaluation, and diagnoses of apathy and…”
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Anosognosia is a significant predictor of apathy in Alzheimer's disease by Starkstein, Sergio E, Brockman, Simone, Bruce, David, Petracca, Gustavo

“…Anosognosia and apathy are among the most common behavioral and psychological disorders of Alzheimer's disease and are significantly associated in…”
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Diagnostic criteria for depression in Parkinson's disease: A study of symptom patterns using latent class analysis by Starkstein, Sergio, Dragovic, Milan, Jorge, Ricardo, Brockman, Simone, Merello, Marcelo, Robinson, Robert G., Bruce, David, Wilson, Mark

“…Although major depression is one of the most frequent psychiatric disorders among patients with Parkinson's disease, diagnostic criteria have yet to be…”
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NON-STEROIDAL ANTI-INFLAMMATORY USE AND LRRK2 PARKINSON’S DISEASE PENETRANCE by Luciano, Marta San, Tanner, Caroline M, Meng, Cheryl, Marras, Connie, Goldman, Samuel M, Lang, Anthony E, Tolosa, Eduardo, Schüle, Birgitt, Langston, J. William, Brice, Alexis, Corvol, Jean-Christophe, Goldwurm, Stefano, Klein, Christine, Brockman, Simone, Berg, Daniela, Brockmann, Kathrin, Ferreira, Joachim J, Tazir, Meriem, Mellick, George D., Sue, Carolyn M, Hasegawa, Kazuko, Tan, Eng King, Bressman, Susan, Saunders-Pullman, Rachel

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The Impact of Emotional Distress on Motor Blocks and Festination in Parkinson’s Disease by Starkstein, Sergio, Dragovic, Milan, Brockman, Simone, Wilson, Mark, Bruno, Veronica, Merello, Marcelo

“…Recent studies suggest that depression and anxiety in patients with Parkinson’s disease may predispose them to freezing. Although festination is also frequent,…”
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Apathy and Parkinson’s Disease by Starkstein, Sergio E., Brockman, Simone

“…Opinion statement Apathy, a frequent finding in Parkinson’s disease (PD), is significantly associated with depression and dementia. Few studies have examined…”
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The Structured Interview for Insight and Judgment in Dementia: Development and validation of a new instrument to assess awareness in patients with dementia by Parrao, Teresa, Brockman, Simone, Bucks, Romola S, Bruce, David G, Davis, Wendy A, Hatch, Katherine K, Leavy, Tammy L, Axten, Christine A.P, Starkstein, Sergio E

“…Abstract Introduction Poor insight about their cognitive and functional deficits is highly prevalent in patients with Alzheimer's disease (AD); however, there…”
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