Search Results - "Brockes, J P"

Reversal of Muscle Differentiation During Urodele Limb Regeneration by Lo, Donald C., Allen, Francesca, Brockes, Jeremy P.

“…Recent studies suggest that maintenance of the differentiated state requires continuous regulation. Limb regeneration in urodele amphibians provides a context…”
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Introduction of a Retinoid Reporter Gene into the Urodele Limb Blastema by Brockes, Jeremy P.

“…After amputation of the limb of an adult urodele amphibian at any point along the proximodistal axis, blastemal cells (the progenitor cells of the regenerate)…”
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Amphibian Limb Regeneration: Rebuilding a Complex Structure by Brockes, Jeremy P.

“…The ability to regenerate complex structures is widespread in metazoan phylogeny, but among vertebrates the urodele amphibians are exceptional. Adult urodeles…”
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The PML-Retinoic Acid Receptor α Translocation Converts the Receptor from an Inhibitor to a Retinoic Acid-Dependent Activator of Transcription Factor AP-1 by Doucas, Vassilis, Brockes, Jeremy P., Yaniv, Moshe, de The, Hugues, Dejean, Anne

“…We report here that the fusion of PML, a nuclear protein defined by the t(15;17) chromosomal translocation in acute promyelocytic leukemia, with retinoic acid…”
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Position dependent expression of a homeobox gene transcript in relation to amphibian limb regeneration by Savard, P., Gates, P. B., Brockes, J. P.

“…Adult urodele amphibians such as the newt Notophthalmus viridescens are capable of regenerating their limbs and tail by formation of a blastema, a growth zone…”
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Identification and purification of glial growth factor by Lemke, GE, Brockes, JP

“…Cultured rat Schwann cells are stimulated to divide by a protein growth factor, present in extracts of bovine brain and pituitary, which we have named glial…”
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Generation of mononucleate cells from post-mitotic myotubes proceeds in the absence of cell cycle progression by Velloso, Cristiana P., Kumar, Anoop, Tanaka, Elly M., Brockes, Jeremy P.

“…The remarkable regenerative ability of adult urodele amphibians depends in part on the plasticity of differentiated cells at the site of injury. Limb…”
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Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes by Bettencourt-Dias, Monica, Mittnacht, Sybille, Brockes, Jeremy P

“…Adult newt cardiomyocytes, in contrast to their mammalian counterparts, can proliferate after injury and contribute to the functional regeneration of the…”
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The Newt Ortholog of CD59 Is Implicated in Proximodistal Identity during Amphibian Limb Regeneration by da Silva, Sara Morais, Gates, Phillip B., Brockes, Jeremy P.

“…The proximodistal identity of a newt limb regeneration blastema is respecified by exposure to retinoic acid, but its molecular basis is unclear. We identified…”
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Identification of a novel retinoic acid receptor in regenerative tissues of the newt by Ragsdale, Clifton W, Petkovich, Martin, Gates, Phillip B, Chambon, Pierre, Brockes, Jeremy P

“…In urodele amphibians, the progenitor cells that regenerate amputated limbs (known as the blastema) normally replace only the missing structures. After…”
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The nerve dependence of amphibian limb regeneration by BROCKES, J. P

“…The regeneration of limbs in urodele amphibians is a context where the developing and regenerating peripheral nervous system interacts with the mechanisms of…”
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Plasticity of Retrovirus-Labelled Myotubes in the Newt Limb Regeneration Blastema by Kumar, Anoop, Velloso, Cristiana P., Imokawa, Yutaka, Brockes, Jeremy P.

“…Two important indices of myogenic differentiation are the formation of syncytial myotubes and the postmitotic arrest from the cell cycle, both of which occur…”
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Monoclonal antibodies to the cells of a regenerating limb by KINTNER, C. R, BROCKES, J. P

“…Monoclonal antibodies were raised against differentiated cells, and blastemal cells from regenerating limbs of adult newts ( Notophthalmus viridescens ) and…”
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Identification and expression of a regeneration-specific homeobox gene in the newt limb blastema by BROWN, R, BROCKES, J. P

“…Adult urodele amphibians are able to regenerate their limbs through the formation of a blastema, a growth zone of undifferentiated mesenchymal cells that…”
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Synthesis and release of 9-cis retinoic acid by the urodele wound epidermis by Viviano, Carolyn M., Horton, Claire E., Maden, Malcolm, Brockes, Jeremy P.

“…The wound epidermis is a transient secretory epithelium that apposes the mesenchymal blastema of a regenerating urodele limb, and is required for regeneration…”
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Expression and Activity of the Newt Msx-1 Gene in Relation to Limb Regeneration by Crews, Lee, Gates, Phillip B., Brown, Robin, Joliot, Alain, Foley, Charlotte, Brockes, Jeremy Patrick, Gann, Alexander A. F.

“…The Msx-1 homeobox gene is expressed in various contexts during vertebrate development, including the progress zone of the avian and mouse limb bud. Expression…”
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Transfer of Scrapie Prion Infectivity by Cell Contact in Culture by Kanu, Nnennaya, Imokawa, Yutaka, Drechsel, David N., Williamson, R. Anthony, Birkett, Christopher R., Bostock, Christopher J., Brockes, Jeremy P.

“…When a cell is infected with scrapie prions, newly synthesized molecules of the prion protein PrPC are expressed at the cell surface and may subsequently be…”
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Mitogenic Growth Factors and Nerve Dependence of Limb Regeneration by Brockes, Jeremy P.

“…Regeneration of the amphibian limb after amputation depends on division of blastemal cells, the progenitor cells of the regenerate. This division is…”
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Regeneration as an evolutionary variable by BROCKES, JEREMY P., KUMAR, ANOOP, VELLOSO, CRISTIANA P.

“…Regeneration poses a distinctive set of problems for evolutionary biologists, but there has been little substantive progress since these issues were clearly…”
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Retinoic acid and limb regeneration by BROCKES, J. P

“…A key problem in the study of vertebrate development is to determine the molecular basis of positional value along a developmental axis. In amphibian…”
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