Search Results - "Brockbank, Kelvin GM"
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The Devil’s advocate regarding use of ME2so for cryopreservation of cell and tissue transplant therapies
Published in Cryobiology (01-12-2023)Get full text
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C-20: Tissue vitrification
Published in Cryobiology (01-12-2014)“…Application of the original tissue vitrification method developed by Fahy and used by my research group for rabbit blood vessels and articular cartilage has…”
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The Grand Challenges of Organ Banking: Proceedings from the first global summit on complex tissue cryopreservation
Published in Cryobiology (01-04-2016)“…The first Organ Banking Summit was convened from Feb. 27 - March 1, 2015 in Palo Alto, CA, with events at Stanford University, NASA Research Park, and Lawrence…”
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Culturing with trehalose produces viable endothelial cells after cryopreservation
Published in Cryobiology (01-06-2012)“…Dimethylsulfoxide, the most commonly employed cryoprotectant for cells, has well documented cytotoxic effects in patients. Among the compounds available that…”
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The Myth of Cryopreservation of Heart Valves
Published in The FASEB journal (01-04-2013)“…Abstract only Allografts represent almost perfect heart valve substitutes with optimal hemodynamic characteristics and resistance to infections. Disadvantages…”
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Vitrification of porcine articular cartilage
Published in Cryobiology (01-04-2010)“…The limited availability of fresh osteochondral allograft tissues necessitates the use of banking for long-term storage. A vitrification solution containing a…”
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Effects on human heart valve immunogenicity in vitro by high concentration cryoprotectant treatment
Published in Journal of tissue engineering and regenerative medicine (01-02-2018)“…It has been shown previously that cryopreservation, using an ice‐free cryopreservation method with the cryoprotectant formulation VS83, beneficially modulated…”
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The performance of ice-free cryopreserved heart valve allografts in an orthotopic pulmonary sheep model
Published in Biomaterials (01-07-2010)“…Abstract Transplantation of cryopreserved heart valves (allografts) is limited by immune responses, inflammation, subsequent structural deterioration and an…”
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Cyclic strain improves strength and function of a collagen-based tissue-engineered vascular media
Published in Tissue engineering. Part A (01-10-2010)“…Tissue-engineered blood vessels may provide a solution to the lack of suitable blood vessels for coronary and peripheral vessel bypass grafting. Cyclic strain…”
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Ice-free cryopreservation of heart valve allografts: better extracellular matrix preservation in vivo and preclinical results
Published in Cell and tissue banking (01-12-2012)“…The purpose of this study was evaluation of an ice-free cryopreservation method for heart valves in an allogeneic juvenile pulmonary sheep implant model and…”
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Comparison and evaluation of biomechanical, electrical, and biological methods for assessment of damage to tissue collagen
Published in Cell and tissue banking (01-09-2016)“…In regard to evaluating tissue banking methods used to preserve or otherwise treat (process) soft allograft tissue, current tests may not be sufficiently…”
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Vitreous cryopreservation maintains the function of vascular grafts
Published in Nature biotechnology (01-03-2000)“…Avoidance of ice formation during cooling can be achieved by vitrification, which is defined as solidification in an amorphous glassy state that obviates ice…”
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Development of pancreas storage solutions: Initial screening of cytoprotective supplements for β-cell survival and metabolic status after hypothermic storage
Published in Biopreservation and biobanking (01-02-2013)“…Insulin-dependent diabetes mellitus is one of the leading causes of death world-wide. Donor-derived pancreas and Islet of Langerhans transplantation are…”
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Quantitative second harmonic generation imaging of cartilage damage
Published in Cell and tissue banking (01-12-2008)“…Cartilage damage was studied using non-invasive multiphoton-excited autofluorescence and quantitative second harmonic generation (SHG) microscopy. Two…”
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RNA isolation from fetal and adult human tissues for transcriptional profiling
Published in Biotechnology journal (01-03-2013)“…Investigations involving rare human tissues that are difficult to acquire due to their scarcity are highly challenging. The need to verify microarray analysis…”
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Characterization of a simplified ice-free cryopreservation method for heart valves
Published in Cell and tissue banking (01-06-2013)“…The aim of the present study was to characterize the hemocompatibility of ice-free cryopreserved heart valves in anticipation of future human trials. Porcine…”
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Serum-free solutions for cryopreservation of cells
Published in In vitro cellular & developmental biology. Animal (01-09-2007)“…With the development of cell-based assays and therapies, the purity of reagents used to grow and maintain cells has become much more important. In particular,…”
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Tissue engineering of a collagen-based vascular media: Demonstration of functionality
Published in Organogenesis (01-10-2010)“…The property of vasoactivity is important for both resistance vessels and larger arteries. Evaluation of smooth muscle cell phenotype is often done in place of…”
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The role of preservation solution on acid-base regulation during machine perfusion of kidneys
Published in Clinical transplantation (01-01-2006)“…: To meet the current clinical organ demand, efficient preservation methods and solutions are needed to increase the number of viable kidneys for…”
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