Search Results - "Brockbank, Kelvin G.M."

Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI Imaging Mass Spectrometry by Angel, Peggi M, Comte-Walters, Susana, Ball, Lauren E, Talbot, Kacey, Mehta, Anand, Brockbank, Kelvin G.M, Drake, Richard R

“…Collagens and elastin form the fundamental framework of all tissues and organs, and their expression and post-translational processing are tightly regulated in…”
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Allogeneic Heart Valve Storage Above the Glass Transition at −80°C by Brockbank, Kelvin G.M., PhD, Wright, Gregory J., BS, Yao, Hai, PhD, Greene, Elizabeth D., LATg, Chen, Zhen Z., MS, Schenke-Layland, Katja, PhD

“…Background Cryopreserved allogeneic heart valves are usually stored and transported below −135°C; however, such methods require expensive equipment for both…”
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Cyclic strain improves strength and function of a collagen-based tissue-engineered vascular media by Schutte, Stacey C, Chen, Zhenzhen, Brockbank, Kelvin G M, Nerem, Robert M

“…Tissue-engineered blood vessels may provide a solution to the lack of suitable blood vessels for coronary and peripheral vessel bypass grafting. Cyclic strain…”
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Optimized Preservation of Extracellular Matrix in Cardiac Tissues: Implications for Long-Term Graft Durability by Schenke-Layland, Katja, PhD, Xie, Jiansong, MD, PhD, Heydarkhan-Hagvall, Sepideh, PhD, Hamm-Alvarez, Sarah F., PhD, Stock, Ulrich A., MD, Brockbank, Kelvin G.M., PhD, MacLellan, W. Robb, MD

“…Background Cryopreservation of human tissues, particularly heart valves, is widespread in clinical practice although the effects of this process on underlying…”
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Vitreous cryopreservation maintains the function of vascular grafts by Taylor, Michael J, Song, Ying C, Khirabadi, Bijan S, Lightfoot, Fred, Brockbank, Kelvin G.M

“…Avoidance of ice formation during cooling can be achieved by vitrification, which is defined as solidification in an amorphous glassy state that obviates ice…”
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The Grand Challenges of Organ Banking: Proceedings from the first global summit on complex tissue cryopreservation by Lewis, Jedediah K., Bischof, John C., Braslavsky, Ido, Brockbank, Kelvin G.M., Fahy, Gregory M., Fuller, Barry J., Rabin, Yoed, Tocchio, Alessandro, Woods, Erik J., Wowk, Brian G., Acker, Jason P., Giwa, Sebastian

“…The first Organ Banking Summit was convened from Feb. 27 - March 1, 2015 in Palo Alto, CA, with events at Stanford University, NASA Research Park, and Lawrence…”
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Vitrification of porcine articular cartilage by Brockbank, Kelvin G.M., Chen, Zhen Z., Song, Ying C.

“…The limited availability of fresh osteochondral allograft tissues necessitates the use of banking for long-term storage. A vitrification solution containing a…”
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Xeno-immunogenicity of ice-free cryopreserved porcine leaflets by Seifert, Martina, PhD, Bayrak, Alexandra, Dipl. Biologist, Stolk, Meaghan, MSc, Souidi, Naima, Dipl. Biologist, Schneider, Maria, Dipl. Biologist, Stock, Ulrich A., MD, Brockbank, Kelvin G.M., PhD

“…Abstract Background Undesirable processes of inflammation, calcification, or immune-mediated reactions are limiting factors in long-term survival of heart…”
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The performance of ice-free cryopreserved heart valve allografts in an orthotopic pulmonary sheep model by Lisy, Milan, Pennecke, Juliane, Brockbank, Kelvin G.M, Fritze, Olaf, Schleicher, Martina, Schenke-Layland, Katja, Kaulitz, Renate, Riemann, Iris, Weber, Corinna N, Braun, Josephine, Mueller, Kerstin E, Fend, Falko, Scheunert, Torsten, Gruber, Achim D, Albes, Johannes M, Huber, Agnes J, Stock, Ulrich A

“…Abstract Transplantation of cryopreserved heart valves (allografts) is limited by immune responses, inflammation, subsequent structural deterioration and an…”
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The Impact of Heat Treatment on Porcine Heart Valve Leaflets by Hepfer, R. Glenn, Chen, Peng, Brockbank, Kelvin G. M., Jones, Alyce L., Burnette, Amanda K., Chen, Zhen, Greene, Elizabeth D., Campbell, Lia H., Yao, Hai

“…The purpose of this study was to determine the impact of elevated temperature exposure in tissue banking on soft tissues. A secondary objective was to…”
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Abstract 19: Extended Graft Survival After Cryopreservation and Storage Below -130°C in a Rat Orthotopic Hind Limb Model by Fidder, Samuel A.J., Oh, Byoungchol, Messner, Franka, Furtmueller, Georg J., Helke, Kristi, Greene, Elizabeth D., Chen, Zhen, Campbell, Lia H., Brandacher, Gerald, Brockbank, Kelvin G.M.

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Preclinical evaluation of ice-free cryopreserved arteries: structural integrity and hemocompatibility by Huber, Agnes J T, Brockbank, Kelvin G M, Riemann, Iris, Schleicher, Martina, Schenke-Layland, Katja, Fritze, Olaf, Wendel, Hans-Peter, Stock, Ulrich A

“…Arterial allografts are routinely employed for reconstruction of infected prosthetic grafts. Usually, banked cryopreserved arteries are used; however, existing…”
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Tissue engineering of a collagen-based vascular media: Demonstration of functionality by Schutte, Stacey C., Chen, Zhenzhen, Brockbank, Kelvin G.M., Nerem, Robert M.

“…The property of vasoactivity is important for both resistance vessels and larger arteries. Evaluation of smooth muscle cell phenotype is often done in place of…”
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Vitrification of bio-engineered epithelial constructs by Campbell, Lia H., Brockbank, Kelvin G.M.

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Ice-free vitrification of complex large tissues by Brockbank, Kelvin G.M.

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Feasibility of vitrification as a storage method for tissue-engineered blood vessels by Dahl, Shannon L M, Chen, Zhenzhen, Solan, Amy K, Brockbank, Kelvin G M, Niklason, Laura E, Song, Ying C

“…It is well established that, in multicellular systems, conventional cryopreservation results in damaging ice formation, both in the cells and in the…”
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Improved tissue cryopreservation using inductive heating of magnetic nanoparticles by Manuchehrabadi, Navid, Gao, Zhe, Zhang, Jinjin, Ring, Hattie L, Shao, Qi, Liu, Feng, McDermott, Michael, Fok, Alex, Rabin, Yoed, Brockbank, Kelvin G M, Garwood, Michael, Haynes, Christy L, Bischof, John C

“…Vitrification, a kinetic process of liquid solidification into glass, poses many potential benefits for tissue cryopreservation including indefinite storage,…”
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The promise of organ and tissue preservation to transform medicine by Giwa, Sebastian, Lewis, Jedediah K, Alvarez, Luis, Langer, Robert, Roth, Alvin E, Church, George M, Markmann, James F, Sachs, David H, Chandraker, Anil, Wertheim, Jason A, Rothblatt, Martine, Boyden, Edward S, Eidbo, Elling, Lee, W P Andrew, Pomahac, Bohdan, Brandacher, Gerald, Weinstock, David M, Elliott, Gloria, Nelson, David, Acker, Jason P, Uygun, Korkut, Schmalz, Boris, Weegman, Brad P, Tocchio, Alessandro, Fahy, Greg M, Storey, Kenneth B, Rubinsky, Boris, Bischof, John, Elliott, Janet A W, Woodruff, Teresa K, Morris, G John, Demirci, Utkan, Brockbank, Kelvin G M, Woods, Erik J, Ben, Robert N, Baust, John G, Gao, Dayong, Fuller, Barry, Rabin, Yoed, Kravitz, David C, Taylor, Michael J, Toner, Mehmet

“…The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create public health benefits on par with…”
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Ice control during cryopreservation of heart valves and maintenance of post-warming cell viability by Brockbank, Kelvin G.M., Chen, Zhenzhen, Greene, Elizabeth D., Campbell, Lia H.

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The future of partial heart transplantation by Rajab, Taufiek K., Vogel, Andrew D., Alexander, Vincent S., Brockbank, Kelvin G.M., Turek, Joseph W.

“…Heart valve replacement in children is an unsolved problem in congenital cardiac surgery because state-of-the-art heart valve implants do not grow. This leads…”
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