Search Results - "Brock, Jonathan"

Equivalence of Protein Inventories Obtained from Formalin-fixed Paraffin-embedded and Frozen Tissue in Multidimensional Liquid Chromatography-Tandem Mass Spectrometry Shotgun Proteomic Analysis by Sprung, Robert W., Brock, Jonathan W.C., Tanksley, Jarred P., Li, Ming, Washington, Mary Kay, Slebos, Robbert J.C., Liebler, Daniel C.

“…Formalin-fixed paraffin-embedded (FFPE) tissue specimens comprise a potentially valuable resource for retrospective biomarker discovery studies, and recent…”
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Enrichment and Analysis of Nonenzymatically Glycated Peptides:  Boronate Affinity Chromatography Coupled with Electron-Transfer Dissociation Mass Spectrometry by Zhang, Qibin, Tang, Ning, Brock, Jonathan W. C, Mottaz, Heather M, Ames, Jennifer M, Baynes, John W, Smith, Richard D, Metz, Thomas O

“…Nonenzymatic glycation of peptides and proteins by d-glucose has important implications in the pathogenesis of diabetes mellitus, particularly in the…”
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Identification of protein succination as a novel modification of tubulin by Piroli, Gerardo G, Manuel, Allison M, Walla, Michael D, Jepson, Matthew J, Brock, Jonathan W C, Rajesh, Mathur P, Tanis, Ross M, Cotham, William E, Frizzell, Norma

“…Protein succination is a stable post-translational modification that occurs when fumarate reacts with cysteine residues to generate 2SC…”
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Intravascular Ultrasound (IVUS) Provides the Filling for the Angiogram's Crust: Benefits of IVUS in Pediatric Interventional Cardiology by Heyden, Caitlin M, Brock, Jonathan E, Ratnayaka, Kanishka, Moore, John W, El-Said, Howaida G

“…Intravascular ultrasound (IVUS) is a catheter-based imaging modality that generates cross-sectional views of vessel walls and lumens. This technique is used in…”
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Improved Methods for the Enrichment and Analysis of Glycated Peptides by Zhang, Qibin, Schepmoes, Athena A, Brock, Jonathan W. C, Wu, Si, Moore, Ronald J, Purvine, Samuel O, Baynes, John W, Smith, Richard D, Metz, Thomas O

“…Nonenzymatic glycation of tissue proteins has important implications in the development of complications of diabetes mellitus. Herein we report improved…”
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Evaluation of Strong Cation Exchange versus Isoelectric Focusing of Peptides for Multidimensional Liquid Chromatography-Tandem Mass Spectrometry by Slebos, Robbert J. C, Brock, Jonathan W. C, Winters, Nancy F, Stuart, Sarah R, Martinez, Misti A, Li, Ming, Chambers, Mathew C, Zimmerman, Lisa J, Ham, Amy J, Tabb, David L, Liebler, Daniel C

“…Shotgun proteome analysis platforms based on multidimensional liquid chromatography-tandem mass spectrometry (LC-MS/MS) provide a powerful means to discover…”
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Increased methionine sulfoxide content of apoA-I in type 1 diabetes by Brock, Jonathan W.C., Jenkins, Alicia J., Lyons, Timothy J., Klein, Richard L., Yim, Eunsil, Lopes-Virella, Maria, Carter, Rickey E., (DCCT/EDIC) Research Group, Thorpe, Suzanne R., Baynes, John W.

“…Cardiovascular disease is a major cause of morbidity and premature mortality in diabetes. HDL plays an important role in limiting vascular damage by removing…”
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Succination of Protein Thiols during Adipocyte Maturation: A BIOMARKER OF MITOCHONDRIAL STRESS by Nagai, Ryoji, Brock, Jonathan W, Blatnik, Matthew, Baatz, John E, Bethard, Jennifer, Walla, Michael D, Thorpe, Suzanne R, Baynes, John W, Frizzell, Norma

“…Although obesity is a risk factor for development of type 2 diabetes and chemical modification of proteins by advanced glycoxidation and lipoxidation end…”
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Posttranslational regulation of thioredoxin-interacting protein by Robinson, Katherine A, Brock, Jonathan W, Buse, Maria G

“…Thioredoxin-interacting protein (Txnip) is a metabolic regulator, which modulates insulin sensitivity and likely plays a role in type 2 diabetes. We studied…”
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Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis by Brock, Jonathan W. C., Cotham, William E., Thorpe, Suzanne R., Baynes, John W, Ames, Jennifer M.

“…Analysis of the broad range of trace chemical modifications of proteins in biological samples is a significant challenge for modern mass spectrometry…”
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Comment on Color Loss in Ethanolic Solutions of Chlorophyll a by Brock, Jonathan R, Rosa, Bryan Q, Kang, Jonghoon

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Proteomic Analysis of the Site Specificity of Glycation and Carboxymethylation of Ribonuclease by Brock, Jonathan W. C, Hinton, Davinia J. S, Cotham, William E, Metz, Thomas O, Thorpe, Suzanne R, Baynes, John W, Ames, Jennifer M

“…Proteomic analysis using electrospray liquid chromatography−mass spectrometry (ESI−LC−MS) has been used to compare the sites of glycation (Amadori adduct…”
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Proteomic Analysis of Arginine Adducts on Glyoxal-modified Ribonuclease by Cotham, William E, Metz, Thomas O, Ferguson, P Lee, Brock, Jonathan W C, Hinton, Davinia J S, Thorpe, Suzanne R, Baynes, John W, Ames, Jennifer M

“…Accumulation of advanced glycation end-products (AGEs) on proteins is associated with the development of diabetic complications. Although the overall extent of…”
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Formation of methionine sulfoxide during glycoxidation and lipoxidation of ribonuclease A by Brock, Jonathan W.C., Ames, Jennifer M., Thorpe, Suzanne R., Baynes, John W.

“…Chemical modification of proteins by reactive oxygen species affects protein structure, function and turnover during aging and chronic disease. Some of this…”
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Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products by Mera, Katsumi, Nagai, Mime, Brock, Jonathan W.C., Fujiwara, Yukio, Murata, Toshinori, Maruyama, Toru, Baynes, John W., Otagiri, Masaki, Nagai, Ryoji

“…Immunohistochemical approaches have been widely used in the localization and quantification of advanced glycation end-products (AGEs). Traditional approaches…”
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Effect of Glucose Concentration on Formation of AGEs in Erythrocytes in Vitro by NAGAI, RYOJI, DEEMER, ELIZABETH K., BROCK, JONATHAN W., THORPE, SUZANNE R., BAYNES, JOHN W.

“…: Posttranslational modifications, such as advanced glycoxidation and lipoxidation end products (AGE/ALEs), are implicated in the pathogenesis of diabetic…”
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Abstract 11645: Use of an Electronic Health Record to Identify Implantable Cardiac Rhythm Device Lead Failure by Brock, Jonathan, Bundy, Richa, Rosenthal, Gary, Rodgers, Larisa, Bhave, Prashant

“…IntroductionElectronic health records (EHR) offer the potential to facilitate research examining the real-world effectiveness and safety of medical…”
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BEING “DELTA” PREEXCITED HEART: A CASE OF ORTHODROMIC REENTRANT TACHYCARDIA (ORT) AFTER HEART TRANSPLANTATION by Hansen, Ross, Crespo, Eric, Bodziock, George, Brock, Jonathan, Dixon, Jessica, Pisani, Barbara A., Bhave, Prashant D.

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A comparative study of the two leadless pacemakers in clinical practice by Shantha, Ghanshyam, Brock, Jonathan, Singleton, Matthew J, Schmitt, Alexander Joseph, Kozak, Patrick, Bodziock, George, Bradford, Natalie, Whalen, Patrick, Bhave, Prashant

“…AVEIR-VR leadless pacemaker (LP) was recently approved for clinical use. Although trial data were promising, post-approval real world data with regard to its…”
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Look before you place: A bizarre ECG artifact due to lead placement by Brock, Jonathan, Schmitt, Alexander, Bhave, Prashant, Whalen, S. Patrick, Simmons, Tony, Singleton, Matthew, Shantha, Ghanshyam

“…The Electrocardiogram (ECG) is a readily available non-invasive test used in the evaluation of a patient with angina. ECG artifacts are common and stem from a…”
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