Search Results - "Brock, Courtney K."
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Stem cell proliferation is induced by apoptotic bodies from dying cells during epithelial tissue maintenance
Published in Nature communications (05-03-2019)“…Epithelial tissues require the removal and replacement of damaged cells to sustain a functional barrier. Dying cells provide instructive cues that can…”
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A Role for Adipocytes and Adipose Stem Cells in the Breast Tumor Microenvironment and Regenerative Medicine
Published in Frontiers in physiology (29-11-2021)“…Obesity rates are climbing, representing a confounding and contributing factor to many disease states, including cancer. With respect to breast cancer, obesity…”
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Multifunctional profiling of triple-negative breast cancer patient-derived tumoroids for disease modeling
Published in SLAS discovery (01-04-2022)“…3D cell models derived from patient tumors are highly translational tools that can recapitulate the complex genetic and molecular compositions of solid cancers…”
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Expression of Novel Kinase MAP3K19 in Various Cancers and Survival Correlations
Published in Frontiers in bioscience (Landmark. Print) (17-06-2022)“…Mitogen Activated Protein (MAP) kinases are a category of serine/threonine kinases that have been demonstrated to regulate intracellular events including…”
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The effect of obesity on adipose-derived stromal cells and adipose tissue and their impact on cancer
Published in Cancer and metastasis reviews (01-09-2022)“…The significant increase in the incidence of obesity represents the next global health crisis. As a result, scientific research has focused on gaining deeper…”
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Abstract 180: Automation and high content imaging of 3D triple negative breast cancer patient-derived tumoroids assay for compound screening
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Introduction: Currently there are no clinically approved small molecule targeted therapies for triple negative breast cancer, underlining the critical…”
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