Search Results - "Brock, C W"

Improved Methods for the Enrichment and Analysis of Glycated Peptides by Zhang, Qibin, Schepmoes, Athena A, Brock, Jonathan W. C, Wu, Si, Moore, Ronald J, Purvine, Samuel O, Baynes, John W, Smith, Richard D, Metz, Thomas O

“…Nonenzymatic glycation of tissue proteins has important implications in the development of complications of diabetes mellitus. Herein we report improved…”
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Equivalence of Protein Inventories Obtained from Formalin-fixed Paraffin-embedded and Frozen Tissue in Multidimensional Liquid Chromatography-Tandem Mass Spectrometry Shotgun Proteomic Analysis by Sprung, Robert W., Brock, Jonathan W.C., Tanksley, Jarred P., Li, Ming, Washington, Mary Kay, Slebos, Robbert J.C., Liebler, Daniel C.

“…Formalin-fixed paraffin-embedded (FFPE) tissue specimens comprise a potentially valuable resource for retrospective biomarker discovery studies, and recent…”
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Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis by Brock, Jonathan W. C., Cotham, William E., Thorpe, Suzanne R., Baynes, John W, Ames, Jennifer M.

“…Analysis of the broad range of trace chemical modifications of proteins in biological samples is a significant challenge for modern mass spectrometry…”
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Enrichment and Analysis of Nonenzymatically Glycated Peptides:  Boronate Affinity Chromatography Coupled with Electron-Transfer Dissociation Mass Spectrometry by Zhang, Qibin, Tang, Ning, Brock, Jonathan W. C, Mottaz, Heather M, Ames, Jennifer M, Baynes, John W, Smith, Richard D, Metz, Thomas O

“…Nonenzymatic glycation of peptides and proteins by d-glucose has important implications in the pathogenesis of diabetes mellitus, particularly in the…”
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Identification of protein succination as a novel modification of tubulin by Piroli, Gerardo G, Manuel, Allison M, Walla, Michael D, Jepson, Matthew J, Brock, Jonathan W C, Rajesh, Mathur P, Tanis, Ross M, Cotham, William E, Frizzell, Norma

“…Protein succination is a stable post-translational modification that occurs when fumarate reacts with cysteine residues to generate 2SC…”
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Evaluation of Strong Cation Exchange versus Isoelectric Focusing of Peptides for Multidimensional Liquid Chromatography-Tandem Mass Spectrometry by Slebos, Robbert J. C, Brock, Jonathan W. C, Winters, Nancy F, Stuart, Sarah R, Martinez, Misti A, Li, Ming, Chambers, Mathew C, Zimmerman, Lisa J, Ham, Amy J, Tabb, David L, Liebler, Daniel C

“…Shotgun proteome analysis platforms based on multidimensional liquid chromatography-tandem mass spectrometry (LC-MS/MS) provide a powerful means to discover…”
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Increased methionine sulfoxide content of apoA-I in type 1 diabetes by Brock, Jonathan W.C., Jenkins, Alicia J., Lyons, Timothy J., Klein, Richard L., Yim, Eunsil, Lopes-Virella, Maria, Carter, Rickey E., (DCCT/EDIC) Research Group, Thorpe, Suzanne R., Baynes, John W.

“…Cardiovascular disease is a major cause of morbidity and premature mortality in diabetes. HDL plays an important role in limiting vascular damage by removing…”
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Proteomic Analysis of Arginine Adducts on Glyoxal-modified Ribonuclease by Cotham, William E, Metz, Thomas O, Ferguson, P Lee, Brock, Jonathan W C, Hinton, Davinia J S, Thorpe, Suzanne R, Baynes, John W, Ames, Jennifer M

“…Accumulation of advanced glycation end-products (AGEs) on proteins is associated with the development of diabetic complications. Although the overall extent of…”
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Proteomic Analysis of the Site Specificity of Glycation and Carboxymethylation of Ribonuclease by Brock, Jonathan W. C, Hinton, Davinia J. S, Cotham, William E, Metz, Thomas O, Thorpe, Suzanne R, Baynes, John W, Ames, Jennifer M

“…Proteomic analysis using electrospray liquid chromatography−mass spectrometry (ESI−LC−MS) has been used to compare the sites of glycation (Amadori adduct…”
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Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products by Mera, Katsumi, Nagai, Mime, Brock, Jonathan W.C., Fujiwara, Yukio, Murata, Toshinori, Maruyama, Toru, Baynes, John W., Otagiri, Masaki, Nagai, Ryoji

“…Immunohistochemical approaches have been widely used in the localization and quantification of advanced glycation end-products (AGEs). Traditional approaches…”
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Formation of methionine sulfoxide during glycoxidation and lipoxidation of ribonuclease A by Brock, Jonathan W.C., Ames, Jennifer M., Thorpe, Suzanne R., Baynes, John W.

“…Chemical modification of proteins by reactive oxygen species affects protein structure, function and turnover during aging and chronic disease. Some of this…”
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Pleiotrophin is an abundant protein in dissociative extracts of bovine fetal epiphyseal cartilage and nasal cartilage from newborns by Neame, P J, Young, C N, Brock, C W, Treep, J T, Ganey, T M, Sasse, J, Rosenberg, L C

“…An abundant protein that is identical to the growth-associated protein pleiotrophin (PTN) has been isolated from dissociative extracts of bovine nasal and…”
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HOW THE CONFEDERATE ARMY WAS VACCINATED by Brock, C W

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Canine position as an aid in cephalometric diagnosis by Brock, W C

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Sex Differences in the Adequacy of Pain Management Among Patients Referred to a Multidisciplinary Cancer Pain Clinic by Donovan, Kristine A., PhD, Taliaferro, Lindsay A., MS, MPH, Brock, Charles W., MD, Bazargan, Sadaf, MD

“…Abstract Few studies have evaluated sex differences in the adequacy of pain management in cancer. Existing studies have been marked by methodological…”
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Enrichment and Analysis of Non-enzymatically Glycated Peptides: Boronate Affinity Chromatography Coupled with Electron Transfer Dissociation Mass Spectrometry by Zhang, Qibin, Tang, Ning, Brock, Jonathan W. C., Mottaz, Heather M., Ames, Jennifer M., Baynes, John W., Smith, Richard D., Metz, Thomas O.

“…Non-enzymatic glycation of peptides and proteins by D-glucose has important implications in the pathogenesis of diabetes mellitus, particularly in the…”
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Proteomic Method for the Quantification of Methionine Sulfoxide by BROCK, J W C, COTHAM, W C, AMES, J M, THORPE, S R, BAYNES, J W

“…: Glycoxidation and lipoxidation reactions contribute to the chemical modification of proteins during the Maillard reaction. Reactive oxygen species, produced…”
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Effect of Glucose Concentration on the Formation of Advanced Glycation End Products in Erythrocytes in Vitro by DEEMER, E K, NAGAI, R, BROCK, J W C, THORPE, S R, BAYNES, J W

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SP9 Adapting Shotgun Proteomics Platforms for Clinical Proteomics by Liebler, D. C., Brock, J. W. C., Winters, N. F., Zimmerman, L. J., Ham, A. L., Sobecki, S. M., Wernke, G. R., Slebos, R., Tabb, D. L.

“…Analysis of tissues from cancers, precancers, and normal tissues provides a means to identify candidate markers for disease detection. The only proteomic…”
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Mass spectrometric analysis of glucose-modified ribonuclease by Cotham, W E, Hinton, D J S, Metz, T O, Brock, J W C, Thorpe, S R, Baynes, J W, Ames, J M

“…RNase A (1 mM) was incubated with glucose (0.4 M) at 37 degrees C for up to 14 days in phosphate buffer (0.2 M, pH 7.4), digested with trypsin and analysed by…”
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