Search Results - "Brix, Thomas H."

A critical review and meta-analysis of the association between overt hyperthyroidism and mortality by Brandt, Frans, Green, Anders, Hegedüs, Laszlo, Brix, Thomas H

“…BackgroundOvert hyperthyroidism has been associated with cardiac arrhythmias, hypercoagulopathy, stroke, and pulmonary embolism, all of which may increase…”
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European Thyroid Association (ETA) and Thyroid Federation International (TFI) Joint Position Statement on the Interchangeability of Levothyroxine Products in EU Countries by Fliers, Eric, Demeneix, Barbara, Bhaseen, Ashok, Brix, Thomas H.

“…Several European countries have seen major health issues after a switch from one levothyroxine brand to another, as well as following the introduction of…”
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Hypothyroid women have persistently higher oxidative stress compared to healthy controls by Riis, Kamilla Ryom, Larsen, Camilla, Medici, Bjarke Røssner, Jensen, Christian Zinck, Winther, Kristian H, Larsen, Emil List, Ellervik, Christina, la Cour, Jeppe Lerche, Hegedus, Laszlo, Brix, Thomas Heiberg, Poulsen, Henrik Enghusen, Knop, Filip K, Nygaard, Birte, Bonnema, Steen Joop

“…Objective: Some studies suggest that hypothyroidism is associated with increased oxidative stress. Urinary excretion of 8-oxo-7,8-dihydroguanosine (8-oxoGuo)…”
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The relative importance of genetic and environmental effects for the early stages of thyroid autoimmunity: a study of healthy Danish twins by Hansen, Pia S, Brix, Thomas H, Iachine, Ivan, Kyvik, Kirsten O, Hegedüs, Laszlo

“…Objective: In euthyroid individuals, autoantibodies to thyroid peroxidase (TPOab) and thyroglobulin (Tgab) are regarded as early markers of thyroid…”
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Treating the thyroid in the presence of Graves’ ophthalmopathy by Hegedüs, Laszlo, MD, DMSc, Bonnema, Steen J., MD, PhD, Smith, Terry J., MD, Brix, Thomas H., MD, PhD

“…The etiology of Graves’ orbitopathy (GO) remains enigmatic. Optimal therapeutic choices for the hyperthyroidism associated with Graves’ disease (GD) in the…”
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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and thyroid disease. An update by Brix, Thomas H., Hegedüs, Laszlo

“…Purpose of review Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with excess morbidity and mortality in patients with…”
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A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase by Nielsen, Claus H, Brix, Thomas H, Leslie, R. Graham Q, Hegedüs, Laszlo

“…Abstract The role of thyroid peroxidase (TPO) antibodies (TPOAbs) in the pathogenesis of autoimmune thyroid disease is unclear. We selected sera with a high…”
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Risk and course of SARS-CoV-2 infection in patients treated for hypothyroidism and hyperthyroidism by Brix, Thomas H, Hegedüs, Laszlo, Hallas, Jesper, Lund, Lars C

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Increased risk of dementia in hypothyroidism: A Danish nationwide register‐based study by Thvilum, Marianne, Brandt, Frans, Lillevang‐Johansen, Mads, Folkestad, Lars, Brix, Thomas H., Hegedüs, Laszlo

“…Objective Globally, the prevalence of individuals with dementia is increasing, and identification of risk factors is of paramount interest. Using…”
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Twin study of genetic and aging effects on X chromosome inactivation by KRISTIANSEN, Marianne, KNUDSEN, Gun P. S, BATHUM, Lise, NAUMOVA, Anna K, SØRENSEN, Thorkild I. A, BRIX, Thomas H, SVENDSEN, Anders J, CHRISTENSEN, Kaare, KYVIK, Kirsten O, ØRSTAVIK, Karen H

“…To investigate the genetic influence on X chromosome inactivation and on age-related skewing of X inactivation, in particular, we analysed the X inactivation…”
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Low Serum Thyrotropin Level and Duration of Suppression as a Predictor of Major Osteoporotic Fractures—The OPENTHYRO Register Cohort by Abrahamsen, Bo, Jørgensen, Henrik L, Laulund, Anne Sofie, Nybo, Mads, Brix, Thomas H, Hegedüs, Laszlo

“…ABSTRACT The relationship between thyrotoxicosis and osteoporotic fractures remains controversial, particularly in men. Register‐based cohort study including…”
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2021 European Thyroid Association Guidelines for the Management of Iodine-Based Contrast Media-Induced Thyroid Dysfunction by Bednarczuk, Tomasz, Brix, Thomas H., Schima, Wolfgang, Zettinig, Georg, Kahaly, George J.

“…Given the fact that a large number of radiological examinations using iodine-based contrast media (ICM) are performed in everyday practice, clinicians should…”
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The Excess Risk of Major Osteoporotic Fractures in Hypothyroidism Is Driven by Cumulative Hyperthyroid as Opposed to Hypothyroid Time: An Observational Register‐Based Time‐Resolved Cohort Analysis by Abrahamsen, Bo, Jørgensen, Henrik L., Laulund, Anne Sofie, Nybo, Mads, Bauer, Doug C., Brix, Thomas H., Hegedüs, Laszlo

“…ABSTRACT The long‐term relationship between hypothyroidism and fracture risk is challenging to dissect because of the modifying influence of subsequent…”
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Subclinical Hyperthyroidism by Hegedüs, Laszlo, Brix, Thomas H, Lillevang-Johansen, Mads

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Epigenome-wide Association Study Shows Differential DNA Methylation of MDC1, KLF9, and CUTA in Autoimmune Thyroid Disease by Lafontaine, Nicole, Shore, Christopher J, Campbell, Purdey J, Mullin, Benjamin H, Brown, Suzanne J, Panicker, Vijay, Dudbridge, Frank, Brix, Thomas H, Hegedüs, Laszlo, Wilson, Scott G, Bell, Jordana T, Walsh, John P

“…Autoimmune thyroid disease (AITD) includes Graves disease (GD) and Hashimoto disease (HD), which often run in the same family. AITD etiology is incompletely…”
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Treatment of Hyperthyroidism Reduces Systemic Oxidative Stress, as Measured by Markers of RNA and DNA Damage by Larsen, Camilla B, Riis, Kamilla R, Winther, Kristian H, Larsen, Emil L, Ellervik, Christina, Hegedüs, Laszlo, Brix, Thomas H, Poulsen, Henrik E, Bonnema, Steen J

“…Abstract Background Whole-body oxidative stress can be estimated by the urine excretion of oxidized guanosine species, 8-oxo-7,8-dihydroguanosine (8-oxoGuo)…”
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A review of the evidence for and against increased mortality in hypothyroidism by Thvilum, Marianne, Brandt, Frans, Brix, Thomas H., Hegedüs, Laszlo

“…Hypothyroidism has been linked with cardiac dysfunction, atherosclerosis, hypertension and coagulopathy, and this increased morbidity might be expected to…”
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Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves' orbitopathy (MINGO): a randomised, observer-masked, multicentre trial by Kahaly, George J, Riedl, Michaela, König, Jochem, Pitz, Susanne, Ponto, Katharina, Diana, Tanja, Kampmann, Elena, Kolbe, Elisa, Eckstein, Anja, Moeller, Lars C, Führer, Dagmar, Salvi, Mario, Curro, Nicola, Campi, Irene, Covelli, Danila, Leo, Marenza, Marinò, Michele, Menconi, Francesca, Marcocci, Claudio, Bartalena, Luigi, Perros, Petros, Wiersinga, Wilmar M, Ayvaz, Göksun, Baldeschi, Lelio, Boborides, Kostas, Boschi, Antonella, Brix, Thomas H, Clarke, Lucy, Dayan, Colin, Daumerie, Chantal, Dickinson, A Jane, Fichter, Nicole, Hegedüs, Laszlo, Konuk, Onur, Krassas, Gerassimos E, Lane, Carol, Lazarus, John, Morris, Dan S, Mourits, Maarten, Nardi, Marco, Neoh, Chris, Orgiazzi, Jacques, Pearce, Simon H S, von Arx, Georg, Zarkovic, Milos

“…European guidelines recommend intravenous methylprednisolone as first-line treatment for active and severe Graves' orbitopathy; however, it is common for…”
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Methimazole and risk of acute pancreatitis by Brix, Thomas H, Lund, Lars C, Henriksen, Daniel P, Folkestad, Lars, Bonnema, Steen J, Hallas, Jesper, Hegedüs, Laszlo

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Mortality in Graves’ orbitopathy is increased and influenced by gender, age and pre-existing morbidity: a nationwide Danish register study by Schwensen, Charlotte F, Brandt, Frans, Hegedüs, Laszlo, Brix, Thomas H

“…Introduction It is unclear whether the excess mortality associated with Graves’ disease differs between individuals with Graves’ orbitopathy (GO) or without…”
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