Search Results - "Britton, Brooke M"

  • Showing 1 - 9 results of 9
Refine Results
  1. 1

    Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair by Liu, Jiaquan, Hanne, Jeungphill, Britton, Brooke M., Bennett, Jared, Kim, Daehyung, Lee, Jong-Bong, Fishel, Richard

    Published in Nature (London) (24-11-2016)
    “…MutS and MutL—the highly conserved core proteins responsible for the repair of mismatched DNA—form sequential stable sliding clamps that together modulate…”
    Get full text
    Journal Article
  2. 2

    Conformational changes in the essential E. coli septal cell wall synthesis complex suggest an activation mechanism by Britton, Brooke M., Yovanno, Remy A., Costa, Sara F., McCausland, Joshua, Lau, Albert Y., Xiao, Jie, Hensel, Zach

    Published in Nature communications (31-07-2023)
    “…The bacterial divisome is a macromolecular machine composed of more than 30 proteins that controls cell wall constriction during division. Here, we present a…”
    Get full text
    Journal Article
  3. 3

    MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair by Liu, Jiaquan, Lee, Ryanggeun, Britton, Brooke M., London, James A., Yang, Keunsang, Hanne, Jeungphill, Lee, Jong-Bong, Fishel, Richard

    Published in Nature communications (22-11-2019)
    “…A shared paradigm of mismatch repair (MMR) across biology depicts extensive exonuclease-driven strand-specific excision that begins at a distant…”
    Get full text
    Journal Article
  4. 4

    Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA by Britton, Brooke M., London, James A., Martin-Lopez, Juana, Jones, Nathan D., Liu, Jiaquan, Lee, Jong-Bong, Fishel, Richard

    Published in The Journal of biological chemistry (01-11-2022)
    “…MutS homologs (MSHs) are highly conserved core components of DNA mismatch repair. Mismatch recognition provokes ATP-binding by MSH proteins that drives a…”
    Get full text
    Journal Article
  5. 5

    MutS homolog sliding clamps shield the DNA from binding proteins by Hanne, Jeungphill, Britton, Brooke M., Park, Jonghyun, Liu, Jiaquan, Martín-López, Juana, Jones, Nathan, Schoffner, Matthew, Klajner, Piotr, Bundschuh, Ralf, Lee, Jong-Bong, Fishel, Richard

    Published in The Journal of biological chemistry (14-09-2018)
    “…Sliding clamps on DNA consist of evolutionarily conserved enzymes that coordinate DNA replication, repair, and the cellular DNA damage response. MutS homolog…”
    Get full text
    Journal Article
  6. 6

    An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore by Liu, Jiaquan, Hanne, Jeungphill, Britton, Brooke M., Shoffner, Matthew, Albers, Aaron E., Bennett, Jared, Zatezalo, Rachel, Barfield, Robyn, Rabuka, David, Lee, Jong-Bong, Fishel, Richard

    Published in Scientific reports (19-11-2015)
    “…Fluorophore labeling of proteins while preserving native functions is essential for bulk Förster resonance energy transfer (FRET) interaction and single…”
    Get full text
    Journal Article
  7. 7
  8. 8

    Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair by Liu, Jiaquan, Hanne, Jeungphill, Britton, Brooke M, Bennett, Jared, Kim, Daehyung, Lee, Jong-Bong, Fishel, Richard

    Published in Nature (London) (24-11-2016)
    “…Mismatched nucleotides arise from polymerase misincorporation errors, recombination between heteroallelic parents and chemical or physical DNA damage. Highly…”
    Get full text
    Journal Article
  9. 9