Search Results - "Brittain, Erica H."
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Assessment of clinical findings, tryptase levels, and bone marrow histopathology in the management of pediatric mastocytosis
Published in Journal of allergy and clinical immunology (01-12-2015)“…Background The management of children with pediatric mastocytosis poses a challenge. This is because there is limited information as to the application of…”
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A primer on strong vs weak control of familywise error rate
Published in Statistics in medicine (30-04-2020)“…Multiple comparison adjustments have a long history, yet confusion remains about which procedures control type 1 error rate in a strong sense and how to show…”
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A randomized double-blind, placebo-controlled study of omalizumab for idiopathic anaphylaxis
Published in Journal of allergy and clinical immunology (01-03-2021)“…Idiopathic anaphylaxis (IA) is a diagnosis of exclusion, thus taking away the option of therapeutic management focused on eliminating the inciting agent…”
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Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease
Published in Journal of allergy and clinical immunology (01-04-2019)“…Caspase activation and recruitment domain 11 (CARD11) encodes a scaffold protein in lymphocytes that links antigen receptor engagement with downstream…”
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Interpreting p-Values and Confidence Intervals Using Well-Calibrated Null Preference Priors
Published in Statistical science (01-11-2022)“…We propose well-calibrated null preference priors for use with one-sided hypothesis tests, such that resulting Bayesian and frequentist inferences agree. Null…”
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Finite sample pointwise confidence intervals for a survival distribution with right-censored data
Published in Statistics in medicine (20-07-2016)“…We review and develop pointwise confidence intervals for a survival distribution with right‐censored data for small samples, assuming only independence of…”
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Causal estimands and confidence intervals associated with Wilcoxon‐Mann‐Whitney tests in randomized experiments
Published in Statistics in medicine (10-09-2018)“…Although the P value from a Wilcoxon‐Mann‐Whitney test is used often with randomized experiments, it is rarely accompanied with a causal effect estimate and…”
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On Causal Inferences for Personalized Medicine: How Hidden Causal Assumptions Led to Erroneous Causal Claims About the D-Value
Published in The American statistician (02-07-2020)“…Personalized medicine asks if a new treatment will help a particular patient, rather than if it improves the average response in a population. Without a causal…”
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Pointwise confidence intervals for a survival distribution with small samples or heavy censoring
Published in Biostatistics (Oxford, England) (01-09-2013)“…We propose a beta product confidence procedure (BPCP) that is a non-parametric confidence procedure for the survival curve at a fixed time for right-censored…”
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Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms
Published in Blood advances (09-05-2023)“…•Characterizing genetic regulation of tryptase expression redefines clinical laboratory reference ranges based on TPSAB1 replication number.•Individualized…”
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Comments on Berry et al.’s response-adaptive randomization platform trial for Ebola
Published in Clinical trials (London, England) (01-10-2016)Get full text
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A valid formulation of the analysis of noninferiority trials under random effects meta-analysis
Published in Biostatistics (Oxford, England) (01-09-2012)“…A noninferiority (NI) trial is sometimes employed to show efficacy of a new treatment when it is unethical to randomize current patients to placebo because of…”
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Does treatment effect depend on control event rate? Revisiting a meta-analysis of suicidality and antidepressant use in children
Published in Clinical trials (London, England) (01-04-2010)“…Background Weisberg et al. (Clin Trials 2009, 6: 109—18) illustrate that entry criteria in randomized trials can lead to results that are biased for the target…”
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Response to commentary
Published in Clinical trials (London, England) (01-04-2010)“…A response to the commentary "Apparent relationship between relative risk and control rate: statistical artifact or selection bias?" by y by Weisburg, Hayden,…”
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Hypomorphic CARD11 mutations associated with diverse immunologic phenotypes with or without atopic disease
Published in Journal of allergy and clinical immunology (28-08-2018)“…This description of a large cohort of patients broadens the spectrum of clinical disease phenotypes linked to CARD11 DN mutations, including atopy, cutaneous…”
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Case-control study of galactorrhea and its relationship to the use of oral contraceptives
Published in Obstetrics and gynecology (New York. 1953) (01-05-1985)“…A case-control study was performed to determine the relationship between galactorrhea and the use of oral contraceptives as well as other risk factors. The…”
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Optimization of Multistage Testing Times and Critical Values in Clinical Trials
Published in Biometrics (01-09-1993)“…Optimal critical values and times of intermediate testing points are determined to minimize expected sample size in a variety of situations. Two-stage and…”
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