Search Results - "Britt, B A"
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A DNA-Damage-Induced Cell Cycle Checkpoint in Arabidopsis
Published in Genetics (Austin) (01-05-2003)“…Although it is well established that plant seeds treated with high doses of gamma radiation arrest development as seedlings, the cause of this arrest is…”
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A shared DNA-damage-response pathway for induction of stem-cell death by UVB and by gamma irradiation
Published in DNA repair (04-09-2010)“…Both UVB radiation and DNA-breaking agents were previously reported to kill Arabidopsis stem cells. We demonstrate that death induced by UVB or by ionizing…”
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3
Repair of DNA damage induced by ultraviolet radiation
Published in Plant physiology (Bethesda) (01-07-1995)Get full text
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4
Cloning and characterization of a gene (UVR3) required for photorepair of 6-4 photoproducts in Arabidopsis thaliana
Published in Nucleic acids research (15-01-1998)“…UV radiation induces two major classes of pyrimidine dimers: the pyrimidine [6-4] pyrimidone photoproduct (6-4 product) and the cyclobutane pyrimidine dimer…”
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Photorepair mutants of Arabidopsis
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-1997)“…UV radiation induces two major DNA damage products, the cyclobutane pyrimidine dimer (CPD) and, at a lower frequency, the pyrimidine (6-4) pyrimidinone dimer…”
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Arabidopsis mutants sensitive to gamma radiation include the homologue of the human repair gene ERCC1
Published in Journal of experimental botany (01-02-2003)“…Mutants sensitive to ionizing radiation in yeast and mammals include an assortment of DNA repair genes. The majority of these DNA repair genes are involved in…”
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A UV-sensitive mutant of Arabidopsis defective in the repair of pyrimidine-pyrimidinone(6-4) dimers
Published in Science (American Association for the Advancement of Science) (17-09-1993)“…Plants are continually subjected to ultraviolet-B (UV-B) irradiation (290 to 320 nanometers) as a component of sunlight, which induces a variety of types of…”
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8
UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana
Published in Genetics (Austin) (01-11-1997)“…Arabidopsis seedlings repair UV-induced DNA damage via light-dependent and independent pathways. The mechanism of the "dark repair" pathway is still unknown…”
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9
Cloning of a 3-methyladenine-DNA glycosylase from Arabidopsis thaliana
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-1994)“…We have isolated an Arabidopsis thaliana cDNA that complements the methyl methanesulfonate-sensitive phenotype of an Escherichia coli double mutant deficient…”
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10
The Arabidopsis UVH1 Gene Is a Homolog of the Yeast Repair Endonuclease RAD1
Published in Plant physiology (Bethesda) (01-10-2000)“…Ultraviolet radiation induces DNA damage products, largely in the form of pyrimidine dimers, that are both toxic and mutagenic. In most organisms, including…”
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A Light-Dependent Pathway for the Elimination of UV-Induced Pyrimidine (6-4) Pyrimidinone Photoproducts in Arabidopsis
Published in The Plant cell (01-09-1994)“…Light-dependent repair of UV-induced cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidinone dimers (6-4 products) was investigated in an…”
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12
Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia
Published in Nature (London) (08-02-1990)“…Malignant hyperthermia (MH) is a potentially lethal condition in which sustained muscle contracture, with attendant hypercatabolic reactions and elevation in…”
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13
Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV
Published in Nucleic acids research (01-10-2007)“…In the absence of the telomerase, telomeres undergo progressive shortening and are ultimately recruited into end-to-end chromosome fusions via the…”
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14
Molecular genetics of DNA repair in higher plants
Published in Trends in Plant Science (1999)“…Damage to DNA occurs in all living things, and the toxicity and/or mutagenicity of the damage products are reduced through the activities of one or more DNA…”
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A substitution of cysteine for arginine 614 in the ryanodine receptor is potentially causative of human malignant hyperthermia
Published in Genomics (San Diego, Calif.) (01-11-1991)“…Malignant hyperthermia (MH) is a devastating, potentially lethal response to anesthetics that occurs in genetically predisposed individuals. The skeletal…”
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Polymorphisms and deduced amino acid substitutions in the coding sequence of the ryanodine receptor (RYR1) gene in individuals with malignant hyperthermia
Published in Genomics (San Diego, Calif.) (01-08-1992)“…Twenty-one polymorphic sequence variants of the RYR1 gene, including 13 restriction fragment length polymorphisms (RFLPs), were identified by sequence analysis…”
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Combined anesthetic- and stress-induced malignant hyperthermia in two offspring of malignant hyperthermic-susceptible parents
Published in Anesthesia and analgesia (01-04-1988)Get full text
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Little or no repair of cyclobutyl pyrimidine dimers is observed in the organellar genomes of the young Arabidopsis seedling
Published in Plant physiology (Bethesda) (01-05-1996)“…A Southern-blot-based, site-specific assay for ultraviolet (UV)induced cyclobutyl pyrimidine dimers (CPDs), employing the CPD-specific enzyme T4 endonuclease…”
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Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy
Published in Canadian journal of anesthesia (01-04-1995)“…To determine the incidence of malignant hyperthermia (MH) reactions after trigger-free anaesthesia in a large population of MH-susceptible (MHS) patients, the…”
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Halothane-dependent release of intracellular Ca2+ in blood cells in malignant hyperthermia
Published in The American journal of physiology (01-03-1990)“…The concentration of ionized cytosolic calcium [( Ca2+]i) was determined in peripheral blood mononuclear cells from normal and malignant hyperthermia…”
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