Search Results - "Brito, Martinez"

LC‐HRMS‐based metabolomics workflow: An alternative strategy for metabolite identification in the antidoping field by Leogrande, Patrizia, Jartdines, Daniel, Martinez‐Brito, Dayamin, Torre, Xavier, Parr, Maria Kristina, Botrè, Francesco

“…Rationale The proposed metabolomic workflow, based on coupling high‐resolution mass spectrometry with computational tools, can be an alternative strategy for…”
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Local Variability Evaluation on Effective Channel Length Extracted With Shift-and-Ratio Method by Brito, Juan Pablo Martinez, Bampi, Sergio

“…In this study, the local variation of the effective channel reduction parameter (<inline-formula> <tex-math notation="LaTeX">{\Delta }{L}={L}_{\text…”
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Detection of urinary metabolites of arimistane in humans by gas chromatography coupled to high‐accuracy mass spectrometry for antidoping analyses by Martinez Brito, Dayamin, Torre, Xavier, Botrè, Francesco

“…Rationale The selection of the most appropriate metabolites of the substances included in the Prohibited List of the World Anti‐Doping Agency (WADA) is…”
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A further insight into methyltestosterone metabolism: New evidences from in vitro and in vivo experiments by Martinez‐Brito, Dayamin, Iannone, Michele, Tatangelo, Maria Antonietta, Molaioni, Francesco, Torre, Xavier, Botrè, Francesco

“…Rationale Although the metabolism of methyltestosterone (MT) has been extensively studied since the 1950s using different techniques, the aim of this study was…”
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Mass spectrometric analysis of 7‐oxygenated androst‐5‐ene structures. Influence in trimethylsilyl derivative formation by Martinez‐Brito, Dayamin, Torre, Xavier, Parr, Maria Kristina, Botrè, Francesco

“…Rationale Several authors have described the generation of androsta‐3,5‐diene‐7‐one structures from androst‐5‐ene‐3,7‐dione or androst‐5‐ene‐3β‐ol‐7‐one under…”
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Detection of urinary arimistane metabolites in humans using liquid chromatography–mass spectrometry: Complementary results to gas chromatography mass spectrometric data and its application to antidoping analyses by Martinez Brito, Dayamin, Leogrande, Patrizia, Botrè, Francesco, Torre, Xavier

“…Rationale The metabolism of arimistane (Arim) was first described in 2015, and androst‐3,5‐diene‐7β‐ol‐17‐one was proposed as the main metabolite excreted in…”
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Investigation of the Physiological and Post‐training Effects of Ecdysteroid Supplementation by Multivariate Analysis of the Human Serum Metabolome by Leogrande, Patrizia, Jardines, Daniel, Brito, Dayamin Martinez, Torre, Xavier, Botrè, Francesco, Luch, Andreas, Diel, Patrick, Parr, Maria Kristina

“…ABSTRACT This work aims to characterize the serum profile of athletes after the administration of ecdysteroids, natural steroid hormones recently reported to…”
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Characterization of the thyroid hormones level in urine by liquid chromatography coupled to mass spectrometry focus in the antidoping field by Martínez Brito, Dayamin, Leogrande, Patrizia, de la Torre, Xavier, Romanelli, Francesco, Botrè, Francesco

“…This paper aims to study the metabolism of thyroid hormones (TH) in urine by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The method was applied…”
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Metabolomics workflow as a driven tool for rapid detection of metabolites in doping analysis. Development and validation by Leogrande, Patrizia, Jardines, Daniel, Martinez‐Brito, Dayamin, Domenici, Eleonora, Torre, Xavier, Parr, Maria Kristina, Botrè, Francesco

“…Rationale This work demonstrates the high potential of combining high‐resolution mass spectrometry with chemometric tools, using metabolomics as a guided tool…”
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Low‐energy electron ionization optimization for steroidomics analysis using high‐resolution mass spectrometry by Leogrande, Patrizia, Jardines, Daniel, Martinez‐Brito, Dayamin, Torre, Xavier, Parr, Maria K., Botrè, Francesco

“…Rationale Systematic electron ionization fragmentation studies of steroids have been performed to elucidate and trace their characteristic fragmentation…”
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Optimization of a method to detect levothyroxine and related compounds in serum and urine by liquid chromatography coupled to triple quadrupole mass spectrometry by Martínez_Brito, Dayamin, Leogrande, Patrizia, de la Torre, Xavier, Botrè, Francesco

“…Thyroid hormones and their derivatives are structurally related to the non-essential amino acid tyrosine (4-hydroxyphenylalanine). However, there are…”
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7‐keto‐DHEAmetabolism in humans. Pitfalls in interpreting the analytical results in the antidoping field by Martinez‐Brito, Dayamin, Torre, Xavier, Colamonici, Cristiana, Curcio, Davide, Botrè, Francesco

“…7‐keto‐DHEA (3β‐hydroxy‐androst‐5‐ene‐7,17‐dione) is included in section S1 of the World Antidoping Agency (WADA) List of Prohibited Substances. The detection…”
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Metabolism of formestane in humans: Identification of urinary biomarkers for antidoping analysis by de la Torre, X., Martinez Brito, D., Colamonici, C., Parr, M.K., Botrè, F.

“…[Display omitted] •Formestane is a substance prohibited in sports by WADA.•There are differences on formestane metabolism depending on the administration…”
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Detection of thyroid hormones in urine by liquid chromatography coupled to tandem mass spectrometry by Martinez Brito, Dayamin, Leogrande, Patrizia, de la Torre, Xavier, Botrè, Francesco

“…Recently, the trend of thyroid hormones (TH) consumption in the sports community has been published. It is known the capacity of the exogenously administered…”
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Membrane crystallization for the recovery of a pharmaceutical compound from waste streams by Brito Martínez, M., Jullok, N., Rodríguez Negrín, Z., Van der Bruggen, B., Luis, P.

“…•Membrane crystallization allows the recovery of the compound G-1 from waste streams.•High flowrates in the feed side impedes the crystallization of G-1.•The…”
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Two Transistors Voltage-Measurement-Based Test Structure for Fast MOSFET Device Mismatch Characterization by Brito, Juan Pablo Martinez, Bampi, Sergio

“…This work presents a test structure targeted to measure MOSFET mismatches with a fast method. It relies on two single-spot voltage measurements in order to…”
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Simultaneous quantification of endogenous biomarkers and detection of testosterone esters in human serum using gas chromatography–high‐resolution mass spectrometry by Martínez_Brito, Dayamín, Leogrande, Patrizia, Jardines, Daniel, Torre, Xavier, Botrè, Francesco

“…Rationale High‐resolution mass spectrometry (HRMS) has been demonstrated to be an alternative platform for quantitative analyses, identifying unknown compounds…”
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Quantification of thyroid hormones and analogs by liquid chromatography coupled to mass spectrometry. Preliminary results in athletes and non‐athletes serum samples by Martínez Brito, Dayamin, Leogrande, Patrizia, Donati, Francesco, Torre, Xavier, Botrè, Francesco

“…This paper aimed to assess a method to measure eight thyroid‐related compounds in serum by liquid chromatography‐mass spectrometry (LC‐MS/MS), to verify the…”
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Thyroid metabolism and supplementation: A review framed in sports environment by Martínez Brito, Dayamin, Botrè, Francesco, Romanelli, Francesco, Torre, Xavier

“…Objectives This paper aimed to consider those features that may suggest a link between thyroid hormones pharmacology and athletes' health based on current…”
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Arimistane: Degradation product or metabolite of 7‐oxo‐DHEA? by Martínez Brito, Dayamín, Leogrande, Patrizia, Colamonici, Cristiana, Curcio, Davide, Botre, Francesco, Torre, Xavier

“…Rationale The instability of androst‐5‐ene‐3,7‐dione structures under acidic conditions is known. The formation of arimistane from 7‐oxo‐DHEA, influenced by…”
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