Association of General and Abdominal Obesity With Hypertension, Dyslipidemia and Prediabetes in the PREDAPS Study

Abstract Introduction and objectives Some anthropometric measurements show a greater capacity than others to identify the presence of cardiovascular risk factors. This study estimated the magnitude of the association of different anthropometric indicators of obesity with hypertension, dyslipidemia,...

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Published in:	Revista española de cardiología (English ed.) Vol. 71; no. 3; pp. 170 - 177
Main Authors:	Sangrós, F. Javier, Giráldez-García, Carolina, Carrillo, Lourdes, Mancera, José, Díez, Javier, Goday, Albert, Serrano, Rosario, García-Soidán, F. Javier, Moreno, Ana, Millaruelo, J. Manuel, Carramiñana, Francisco, Pérez, Francisco Carlos, Iriarte, Yon, Lorenzo, Ángela, Álvarez, Beatriz, Barutell, Lourdes, del Castillo, Mercedes, Navarro, Emma, Malo, Fernando, Cambra, Ainhoa, López, Riánsares, Gutiérrez, Luisa, Boente, Carmen, Mediavilla, J. Javier, Prieto, Luis, Mendo, Luis, Mansilla, M. José, Ortega, Francisco Javier, Borras, Antonia, Sánchez, L. Gabriel, Obaya, J. Carlos, Alonso, Margarita, Gutiérrez, Ángela Trinidad, Suárez, Dulce, Álvarez, J. Carlos, Sáenz, Isabel, Martínez, F. Javier, Casorrán, Ana, Ripoll, Jazmín, Salanova, Alejandro, Innerárity, Jaime, Álvarez, M. del Mar, Artola, Sara, Bedoya, M. Jesús, Poveda, Santiago, Brito, M. Jesús, Iglesias, Rosario, Paniagua, Francisca, Durán, M. Carmen, Sagredo, Julio, Pérez, Pedro P, Gamarra, Javier, Carbonell, Francisco, García-Giralda, Luis, Antón, J. Joaquín, de la Flor, Manuel, Martínez, Rosario, Pardo, José Luis, Ruiz, Antonio, Plana, Raquel, Macía, Ramón, Villaró, Mercè, Babace, Carmen, Torres, José Luis, Blanco, Concepción, Martín, José Luis, Navarro, Jorge, Sanz, Gloria, Colas, Rafael, Cordero, Blanca, de Castro, Cristina, Porta, Nuria, Gómez, María del Carmen, Llanes, Rafael, Rodríguez, J. José, Granero, Esteban, Sánchez, Manuel, Martínez, Juan, Ezkurra, Patxi, Ávila, Luis, Rodríguez, Antonio, Buil, Pilar, Gabriel, Paula, Roura, Pilar, Tarragó, Eduard, Mundet, Xavier, Bosch, Remei, Bobé, M. Isabel, Mata, Manel, Ruiz, Irene, Birules, Marti, Armengol, Oriol, Bilbeny, Beatriz, Cabré, J. José, Cos, Xavier, Pujol, Ramón, Seguí, Mateu, Losada, Carmen, de Santiago, A. María, Muñoz, Pedro
Format:	Journal Article
Language:	English
Published:	Spain 01-03-2018
Subjects:	Adult Aged Anthropometry Cardiovascular Cross-Sectional Studies Dyslipidemias - epidemiology Dyslipidemias - etiology Female Humans Hypertension - epidemiology Hypertension - etiology Incidence Internal Medicine Male Middle Aged Obesity, Abdominal - complications Obesity, Abdominal - epidemiology Prediabetic State - epidemiology Prediabetic State - etiology Prognosis Risk Assessment Risk Factors Spain - epidemiology Hypertension WHR Obesity Obesidad waist-hip ratio waist circumference body mass index Medidas antropométricas WHtR Trastorno del metabolismo de los lípidos Hipertensión Prediabetes HT WC Estado prediabético Abdominal obesity Anthropometric measurements HbA 1c Disorder of lipid metabolism glycosylated hemoglobin waist-height ratio Obesidad abdominal BMI
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Summary:	Abstract Introduction and objectives Some anthropometric measurements show a greater capacity than others to identify the presence of cardiovascular risk factors. This study estimated the magnitude of the association of different anthropometric indicators of obesity with hypertension, dyslipidemia, and prediabetes (altered fasting plasma glucose and/or glycosylated hemoglobin). Methods Cross-sectional analysis of information collected from 2022 participants in the PREDAPS study (baseline phase). General obesity was defined as body mass index ≥ 30 kg/m2 and abdominal obesity was defined with 2 criteria: a) waist circumference (WC) ≥ 102 cm in men/WC ≥ 88 cm in women, and b) waist-height ratio (WHtR) ≥ 0.55. The magnitude of the association was estimated by logistic regression. Results Hypertension showed the strongest association with general obesity in women (OR, 3.01; 95% CI , 2.24-4.04) and with abdominal obesity based on the WHtR criterion in men (OR, 3.65; 95%CI, 2.66-5.01). Hypertriglyceridemia and low levels of high-density lipoprotein cholesterol showed the strongest association with abdominal obesity based on the WHtR criterion in women (OR, 2.49; 95%CI, 1.68-3.67 and OR, 2.70; 95%CI, 1.89-3.86) and with general obesity in men (OR, 2.06; 95%CI, 1.56-2.73 and OR, 1.68; 95%CI, 1.21-2.33). Prediabetes showed the strongest association with abdominal obesity based on the WHtR criterion in women (OR, 2.48; 95%CI, 1.85-3.33) and with abdominal obesity based on the WC criterion in men (OR, 2.33; 95%CI, 1.75-3.08). Conclusions Abdominal obesity indicators showed the strongest association with the presence of prediabetes. The association of anthropometric indicators with hypertension and dyslipidemia showed heterogeneous results.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1885-5857 1885-5857
DOI:	10.1016/j.rec.2017.04.035