Search Results - "Brito, Jôse Mára"

Bronchial eosinophils, neutrophils, and CD8 + T cells influence asthma control and lung function in schoolchildren and adolescents with severe treatment-resistant asthma by Eller, Miriam Cardoso Neves, Pierantozzi Vergani, Karina, Saraiva-Romanholo, Beatriz Mangueira, de Souza Xavier Costa, Natália, de Brito, Jôse Mára, Antonangelo, Leila, Faria, Caroline Silvério, Rodrigues, Joaquim Carlos, Mauad, Thais

“…Studies in adult severe treatment-resistant asthma (STRA) have demonstrated heterogeneous pathophysiology. Studies in the pediatric age group are still scarce,…”
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Acute cardiopulmonary effects induced by the inhalation of concentrated ambient particles during seasonal variation in the city of São Paulo by Brito, Jôse Mára de, Macchione, Mariângela, Yoshizaki, Kelly, Toledo-Arruda, Alessandra Choqueta, Saraiva-Romanholo, Beatriz Mangueira, Andrade, Maria de Fátima, Mauad, Thaís, Rivero, Dolores Helena Rodriguez Ferreira, Saldiva, Paulo Hilário Nascimento

“…Ambient particles may undergo modifications to their chemical composition as a consequence of climatic variability. The determination of whether these changes…”
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Allergic sensitization and exposure to ambient air pollution beginning early in life lead to a COPD-like phenotype in young adult mice by de Souza Xavier Costa, Natália, Mirtes Teles, Aila, de Brito, Jôse Mára, de Barros Mendes Lopes, Thaís, Calciolari Rossi, Renata, Magalhães Arantes Costa, Fernanda, Mangueira Saraiva-Romanholo, Beatriz, Perini, Adenir, Furuya, Tatiane Katsue, Germán Murillo Carrasco, Alexis, Matera Veras, Mariana, Nascimento Saldiva, Paulo Hilário, Chammas, Roger, Mauad, Thais

“…The perinatal period and early infancy are considered critical periods for lung development. During this period, adversities such as environmental exposures,…”
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Pulmonary impact of N-acetylcysteine in a controlled hemorrhagic shock model in rats by Saad, Karen Ruggeri, PhD, Saad, Paulo Fernandes, MD, PhD, Dantas Filho, Luiz, MD, PhD, Brito, Jôse Mára de, PhD, Koike, Marcia Kiyomi, PhD, Zanoni, Fernando Luiz, PhD, Dolhnikoff, Marisa, MD, PhD, Montero, Edna Frasson de Souza, MD, PhD

“…Abstract Background Experimental hemorrhagic shock (HS) is based on controlling bleeding and the treatment of fluid resuscitation to restore tissue oxygenation…”
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Acute exposure to diesel and sewage biodiesel exhaust causes pulmonary and systemic inflammation in mice by de Brito, Jôse Mára, Mauad, Thais, Cavalheiro, Guilherme Franco, Yoshizaki, Kelly, de André, Paulo Afonso, Lichtenfels, Ana Julia F.C., Guimarães, Eliane Tigre, Rivero, Dolores Helena Rodriguez Ferreira, Antonangelo, Leila, Oliveira, Luciano Basto, Pedroso, Luiz Roberto Martins, Macchione, Mariangela, Saldiva, Paulo Hilário Nascimento

“…•Acute exposure to diesel and biodiesel exhaust increased the heart rate variability.•Acute exposure to biodiesel exhaust caused neutrophilic lung…”
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Effects of intrauterine exposure to concentrated ambient particles on allergic sensitization in juvenile mice by de Brito, Jôse Mára, de Ameida, Francine Maria, Arantes-Costa, Fernanda Magalhães, Guimarães, Eliane Tigre, Morgan, Adriana, Mangone, Flavia Rotea, Pavanelli, Ana Carolina, Nagai, Maria Aparecida, Vieira, Rodolfo P., Macchione, Mariângela, Mauad, Thais

“…Effects in the experimental CAPs, HDM and CAPs+HDM groups in relation to the control (FA) group [Display omitted] •PM2.5 prenatal exposure did not increase…”
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Inflammatory and functional responses after (bio)diesel exhaust exposure in allergic sensitized mice. A comparison between diesel and biodiesel by Timmerman, Tirza, de Brito, Jôse Mára, de Almeida, Natalia Madureira, de Almeida, Francine Maria, Arantes-Costa, Fernanda Magalhães, Guimaraes, Eliane Tigre, Lichtenfels, Ana Julia Faria Coimbra, Rivero, Dolores Helena Rodriguez Ferreira, de Oliveira, Regiani Carvalho, de Lacerda, João Paulo Amorim, Moraes, Jamille Moreira, Pimental, Danilo Augusto, Saraiva-Romanholo, Beatriz Mangueira, Saldiva, Paulo Hilário Nascimento, Vieira, Rodolfo de Paula, Mauad, Thais

“…Many cities fail to meet air quality standards, which results in increased risk for pulmonary disorders, including asthma. Human and experimental studies have…”
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Airway wall extracellular matrix changes induced by bronchial thermoplasty in severe asthma by Wijsman, Pieta C, Goorsenberg, Annika W M, Keijzer, Noa, d'Hooghe, Julia N S, Ten Hacken, Nick H T, Shah, Pallav L, Weersink, Els J M, de Brito, Jôse Mara, de Souza Xavier Costa, Natalia, Mauad, Thais, Nawijn, Martijn C, Vonk, Judith M, Annema, Jouke T, Burgess, Janette K, Bonta, Peter I

“…Airway remodeling is a prominent feature of asthma, which involves increased airway smooth muscle mass and altered extracellular matrix composition. Bronchial…”
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COVID-19 induces more pronounced extracellular matrix deposition than other causes of ARDS by de Souza Xavier Costa, Natália, Ribeiro Júnior, Gabriel, do Nascimento, Ellen Caroline Toledo, de Brito, Jôse Mara, Antonangelo, Leila, Faria, Caroline Silvério, Monteiro, Jhonatas Sirino, Setubal, João Carlos, Pinho, João Renato Rebello, Pereira, Roberta Verciano, Seelaender, Marilia, de Castro, Gabriela Salim, Lima, Joanna D C C, de Almeida Monteiro, Renata Aparecida, Duarte-Neto, Amaro Nunes, Saldiva, Paulo Hilário Nascimento, Ferraz da Silva, Luiz Fernando, Dolhnikoff, Marisa, Mauad, Thais

“…Lung fibrosis is a major concern in severe COVID-19 patients undergoing mechanical ventilation (MV). Lung fibrosis frequency in post-COVID syndrome is highly…”
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Hematological changes and cytogenotoxicity in the tilapia Oreochromis niloticus caused by sub-chronic exposures to mercury and selenium by Seriani, Robson, França, Jakeline Galvão, Lombardi, Julio Vicente, Brito, Jôse Mara, Ranzani-Paiva, Maria José Tavares

“…Fish bioassays are valuable tools that can be used to elucidate the toxicological potential of numerous substances that are present in the aquatic environment…”
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Enriched inorganic compounds in diesel exhaust particles induce mitogen-activated protein kinase activation, cytoskeleton instability, and cytotoxicity in human bronchial epithelial cells by Seriani, Robson, Junqueira, Mara S., Carvalho-Sousa, Claudia E., Arruda, Alessandra C.T., Martinez, Diana, Alencar, Adriano M., Garippo, Ana L., Brito, Jôse Mara, Martins, Milton A., Saldiva, Paulo H.N., Negri, Elnara M., Mauad, Thais, Macchione, Mariangela

“…•Diesel exhaust particles (DEP) induce ERK/JNK activation and cytotoxicity in airways cells.•DEP/HEX active JNK that alters cytoskeleton arrangement with…”
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The effects of particulate matter on inflammation of respiratory system: Differences between male and female by Yoshizaki, Kelly, Brito, Jôse Mára, Silva, Luiz Fernando, Lino-dos-Santos-Franco, Adriana, Frias, Daniela Perroni, e Silva, Renata Calciolari Rossi, Amato-Lourenço, Luís Fernando, Saldiva, Paulo Hilário Nascimento, de Fátima Lopes Calvo Tibério, Iolanda, Mauad, Thais, Macchione, Mariangela

“…Air pollution is known to exacerbate respiratory diseases and epidemiological studies have shown that women present more chronic respiratory symptoms than man…”
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Chronic exposure to diesel particles worsened emphysema and increased M2-like phenotype macrophages in a PPE-induced model by Moreira, Alyne Riani, Pereira de Castro, Thamyres Barros, Kohler, Júlia Benini, Ito, Juliana Tiyaki, de França Silva, Larissa Emídio, Lourenço, Juliana Dias, Almeida, Rafael Ribeiro, Santana, Fernanda Roncon, Brito, Jose Mara, Rivero, Dolores Helena Rodriguez Ferreira, Vale, Maria Isabel Cardoso Alonso, Prado, Carla Máximo, Câmara, Niels Olsen Saraiva, Saldiva, Paulo Hilário Nascimento, Olivo, Clarice Rosa, Lopes, Fernanda Degobbi Tenorio Quirino Dos Santos

“…Chronic exposure to ambient levels of air pollution induces respiratory illness exacerbation by increasing inflammatory responses and apoptotic cells in…”
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Acute Cardiovascular and Inflammatory Toxicity Induced by Inhalation of Diesel and Biodiesel Exhaust Particles by Brito, Jôse Mára, Belotti, Luciano, Toledo, Alessandra C., Antonangelo, Leila, Silva, Flávio S., Alvim, Débora S., Andre, Paulo A., Saldiva, Paulo H. N., Rivero, Dolores H. R. F.

“…Analysis of fuel emissions is crucial for understanding the pathogenesis of mortality because of air pollution. The objective of this study is to assess…”
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Tracking the time course of pathological patterns of lung injury in severe COVID-19 by Mauad, Thais, Duarte-Neto, Amaro Nunes, da Silva, Luiz Fernando Ferraz, de Oliveira, Ellen Pierre, de Brito, Jose Mara, do Nascimento, Ellen Caroline Toledo, de Almeida Monteiro, Renata Aparecida, Ferreira, Juliana Carvalho, de Carvalho, Carlos Roberto Ribeiro, do Nascimento Saldiva, Paulo Hilário, Dolhnikoff, Marisa

“…Pulmonary involvement in COVID-19 is characterized pathologically by diffuse alveolar damage (DAD) and thrombosis, leading to the clinical picture of Acute…”
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Chronic exposure of diesel exhaust particles induces alveolar enlargement in mice by Yoshizaki, Kelly, Brito, Jôse Mára, Moriya, Henrique T, Toledo, Alessandra C, Ferzilan, Sandra, Ligeiro de Oliveira, Ana Paula, Machado, Isabel D, Farsky, Sandra H P, Silva, Luiz F F, Martins, Milton A, Saldiva, Paulo H N, Mauad, Thais, Macchione, Mariangela

“…Diesel exhaust particles (DEPs) are deposited into the respiratory tract and are thought to be a risk factor for the development of diseases of the respiratory…”
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Bronchial responsiveness in an elastase-induced mouse model of emphysema by Santos, Luiz Marcelo Oliveira, Cervilha, Daniela Aparecida de Brito, Cabral, Layla Dutra Marinho, Garcia, Érika Kristina Incerpi, Teixeira, Vanessa Pereira, Brito, Jôse Mára, Moriya, Henrique Takachi, Soncini, Roseli

“…Highlights • Methacholine attenuated the airway responsiveness in elastase-induced emphysema in mice. • Collapsed and/or hyperinflated area can modulate…”
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