Search Results - "Brito, Fernanda Carla Ferreira"
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Cilostazol exerts antiplatelet and anti-inflammatory effects through AMPK activation and NF-kB inhibition on hypercholesterolemic rats
Published in Fundamental & clinical pharmacology (01-08-2016)“…This work presents a model of rats fed a high‐cholesterol diet, receiving a long‐term oral administration of cilostazol, a PDE3‐inhibitor. The aim of this…”
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Could cilostazol be beneficial in COVID-19 treatment? Thinking about phosphodiesterase-3 as a therapeutic target
Published in International immunopharmacology (01-03-2021)“…[Display omitted] •Cilostazol as adjuvant in the treatment of COVID-19.•Hyperinflammation and coagulability state contribute to COVID-19 severity.•Cilostazol…”
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Reviewing Atrial Fibrillation Pathophysiology from a Network Medicine Perspective: The Relevance of Structural Remodeling, Inflammation, and the Immune System
Published in Life (Basel, Switzerland) (01-06-2023)“…Atrial fibrillation (AF) is the most common type of sustained arrhythmia. The numerous gaps concerning the knowledge of its mechanism make improving clinical…”
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Anti-atherogenic Effects of a New Thienylacylhydrazone Derivative, LASSBio-788, in Rats Fed a Hypercholesterolemic Diet
Published in Journal of Pharmacological Sciences (2013)“…The compound LASSBio-788 (N-Allyl (2-thienylidene) 3,4-methylenedioxybenzoylhydrazine) is a thienylacylhydrazone derivative shown to have antiplatelet,…”
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Evaluation of the effects produced by subacute tributyltin administration on vascular reactivity of male wistar rats
Published in Toxicology (Amsterdam) (15-01-2022)“…[Display omitted] •Tributyltin inhibited peNOSSer177 activation in vascular smooth muscle cells.•Increased oxidative stress parameters was observed in aortas…”
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Cilostazol attenuates cardiac oxidative stress and inflammation in hypercholesterolemic rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-07-2022)“…Atherosclerosis is a multifactorial chronic disease associated with pro-inflammatory and pro-oxidative cardiovascular states. Cilostazol, a selective…”
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Challenges in Pharmacological Management of Cardiovascular Diseases in Covid-19: do Benefits Outweigh Risks?
Published in International journal of cardiovascular sciences (31-07-2020)Get full text
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Effects of Chloroquine and Hydroxychloroquine on the Cardiovascular System - Limitations for Use in the Treatment of COVID-19
Published in International journal of cardiovascular sciences (01-04-2021)“…Abstract Chloroquine (CQ) and Hydroxychloroquine (HCQ) are antimalarial drugs, with anti-inflammatory properties that justify their use in the treatment of…”
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Subacute administration of cilostazol modulates PLC-γ/PKC-α/p38/NF-kB pathway and plays vascular protective effects through eNOS activation in early stages of atherosclerosis development
Published in Life sciences (1973) (01-11-2023)“…Hypercholesterolemia is an important risk factor for development of cardiovascular disturbances, such as atherosclerosis, and its treatment remains challenging…”
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Tributyltin-induced visceral adiposity is associated with impaired redox balance in white adipose tissue of male rats
Published in Molecular and cellular endocrinology (01-11-2024)“…Tributyltin (TBT) is an organotin compound that has several adverse health effects, including the development of obesity. Although obesity is strongly…”
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A NOVEL ROLE OF LASSBio‐788 IN INHIBITING NF‐&[Kappa]B MEDIATED SIGNALING IN PLATELET OF HYPERCHOLESTEROLEMIC RATS
Published in The FASEB journal (01-04-2017)“…Abstract only…”
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Effects of Chloroquine and Hydroxychloroquine on the Cardiovascular System - Limitations for Use in the Treatment of COVID-19
Published in International journal of cardiovascular sciences (2021)“…Abstract Chloroquine (CQ) and Hydroxychloroquine (HCQ) are antimalarial drugs, with anti-inflammatory properties that justify their use in the treatment of…”
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Impact of Brazil Nut (Bertholletia excelsa, H.B.K.) Supplementation on Body Composition, Blood Pressure, and the Vascular Reactivity of Wistar Rats When Submitted to a Hypersodium Diet
Published in Journal of the American College of Nutrition (01-08-2022)“…Introdution: Endothelium integrity is a key that maintains vascular homeostasis but it can suffer irreversible damage by blood pressure changes, reflecting an…”
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Challenges in Pharmacological Management of Cardiovascular Diseases in Covid-19: do Benefits Outweigh Risks?
Published in International journal of cardiovascular sciences (01-07-2020)Get full text
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